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6CJT
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BU of 6cjt by Molmil
Structure of the SthK cyclic nucleotide-gated potassium channel in complex with cGMP
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CYCLIC GUANOSINE MONOPHOSPHATE, SthK cyclic nucleotide-gated potassium channel
Authors:Nimigean, C.M, Rheinberger, J.
Deposit date:2018-02-26
Release date:2018-08-01
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.
Elife, 7, 2018
7TKT
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BU of 7tkt by Molmil
SthK closed state, cAMP-bound in the presence of detergent
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ...
Authors:Rheinberger, J, Schmidpeter, P.A, Nimigean, C.M.
Deposit date:2022-01-17
Release date:2022-10-26
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Anionic lipids unlock the gates of select ion channels in the pacemaker family.
Nat.Struct.Mol.Biol., 29, 2022
6CJU
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BU of 6cju by Molmil
Structure of the SthK cyclic nucleotide-gated potassium channel in complex with cAMP
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK cyclic nucleotide-gated potassium channel
Authors:Nimigean, C.M, Rheinberger, J.
Deposit date:2018-02-26
Release date:2018-08-01
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.
Elife, 7, 2018
6CJQ
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BU of 6cjq by Molmil
Structure of the SthK cyclic nucleotide-gated potassium channel
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, SthK cyclic nucleotide-gated potassium channel
Authors:Nimigean, C.M, Rheinberger, J.
Deposit date:2018-02-26
Release date:2018-08-01
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.
Elife, 7, 2018
5J7A
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BU of 5j7a by Molmil
Bacteriorhodopsin ground state structure obtained with Serial Femtosecond Crystallography
Descriptor: 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, Bacteriorhodopsin, RETINAL
Authors:Nogly, P, Panneels, V, Nelson, G, Gati, C, Kimura, T, Milne, C, Milathianaki, D, Kubo, M, Wu, W, Conrad, C, Coe, J, Bean, R, Zhao, Y, Bath, P, Dods, R, Harimoorthy, R, Beyerlein, K.R, Rheinberger, J, James, D, DePonte, D, Li, C, Sala, L, Williams, G, Hunter, M, Koglin, J.E, Berntsen, P, Nango, E, Iwata, S, Chapman, H.N, Fromme, P, Frank, M, Abela, R, Boutet, S, Barty, A, White, T.A, Weierstall, U, Spence, J, Neutze, R, Schertler, G, Standfuss, J.
Deposit date:2016-04-06
Release date:2016-08-31
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallography.
Nat Commun, 7, 2016
7NNU
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BU of 7nnu by Molmil
Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs
Descriptor: Conserved hypothetical membrane protein, Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, ...
Authors:Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J.
Deposit date:2021-02-25
Release date:2021-08-18
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Insights into the bilayer-mediated toppling mechanism of a folate-specific ECF transporter by cryo-EM.
Proc.Natl.Acad.Sci.USA, 118, 2021
7NNT
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BU of 7nnt by Molmil
Cryo-EM structure of the folate-specific ECF transporter complex in DDM micelles
Descriptor: Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT, ...
Authors:Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J.
Deposit date:2021-02-25
Release date:2021-08-18
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Insights into the bilayer-mediated toppling mechanism of a folate-specific ECF transporter by cryo-EM.
Proc.Natl.Acad.Sci.USA, 118, 2021
7P7A
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BU of 7p7a by Molmil
SARS-CoV-2 spike protein in complex with sybody#68 in a 2up/1flexible conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(5-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Walter, J.D, Hutter, C.A.J, Garaeva, A.A, Scherer, M, Zimmermann, I, Wyss, M, Rheinberger, J, Ruedin, Y, Earp, J.C, Egloff, P, Sorgenfrei, M, Huerlimann, L.M, Gonda, I, Meier, G, Remm, S, Thavarasah, S, Zimmer, G, Slotboom, D.J, Paulino, C, Plattet, P, Seeger, M.A.
Deposit date:2021-07-19
Release date:2021-08-04
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (4.76 Å)
Cite:Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance.
Embo Rep., 23, 2022
7P77
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BU of 7p77 by Molmil
SARS-CoV-2 spike protein in complex with sybody#15 and sybody#68 in a 3up conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(5-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Walter, J.D, Hutter, C.A.J, Garaeva, A.A, Scherer, M, Zimmermann, I, Wyss, M, Rheinberger, J, Ruedin, Y, Earp, J.C, Egloff, P, Sorgenfrei, M, Huerlimann, L.M, Gonda, I, Meier, G, Remm, S, Thavarasah, S, Zimmer, G, Slotboom, D.J, Paulino, C, Plattet, P, Seeger, M.A.
Deposit date:2021-07-19
Release date:2021-08-04
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance.
Embo Rep., 23, 2022
7P78
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BU of 7p78 by Molmil
SARS-CoV-2 spike protein in complex with sybody#15 and sybody#68 in a 1up/1up-out/1down conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(5-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Walter, J.D, Hutter, C.A.J, Garaeva, A.A, Scherer, M, Zimmermann, I, Wyss, M, Rheinberger, J, Ruedin, Y, Earp, J.C, Egloff, P, Sorgenfrei, M, Huerlimann, L.M, Gonda, I, Meier, G, Remm, S, Thavarasah, S, Zimmer, G, Slotboom, D.J, Paulino, C, Plattet, P, Seeger, M.A.
Deposit date:2021-07-19
Release date:2021-08-04
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance.
Embo Rep., 23, 2022
7P79
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BU of 7p79 by Molmil
SARS-CoV-2 spike protein in complex with sybodyb#15 in a 1up/1up-out/1down conformation.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(5-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Walter, J.D, Hutter, C.A.J, Garaeva, A.A, Scherer, M, Zimmermann, I, Wyss, M, Rheinberger, J, Ruedin, Y, Earp, J.C, Egloff, P, Sorgenfrei, M, Huerlimann, L.M, Gonda, I, Meier, G, Remm, S, Thavarasah, S, Zimmer, G, Slotboom, D.J, Paulino, C, Plattet, P, Seeger, M.A.
Deposit date:2021-07-19
Release date:2021-08-04
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance.
Embo Rep., 23, 2022
7P7B
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BU of 7p7b by Molmil
SARS-CoV-2 spike protein in complex with sybody no68 in a 1up/2down conformation
Descriptor: Spike glycoprotein
Authors:Walter, J.D, Hutter, C.A.J, Garaeva, A.A, Scherer, M, Zimmermann, I, Wyss, M, Rheinberger, J, Ruedin, Y, Earp, J.C, Egloff, P, Sorgenfrei, M, Huerlimann, L.M, Gonda, I, Meier, G, Remm, S, Thavarasah, S, Zimmer, G, Slotboom, D.J, Paulino, C, Plattet, P, Seeger, M.A.
Deposit date:2021-07-19
Release date:2021-08-04
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance.
Embo Rep., 23, 2022
6VY0
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BU of 6vy0 by Molmil
SthK P300A cyclic nucleotide-gated potassium channel in a putative active state, in complex with cAMP
Descriptor: SthK
Authors:Schmidpeter, P.A.M, Rheinberger, J, Nimigean, C.M.
Deposit date:2020-02-25
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6.68 Å)
Cite:Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel.
Nat Commun, 11, 2020
6VXZ
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BU of 6vxz by Molmil
SthK P300A cyclic nucleotide-gated potassium channel in the closed state, in complex with cAMP
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK
Authors:Schmidpeter, P.A.M, Rheinberger, J, Nimigean, C.M.
Deposit date:2020-02-25
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel.
Nat Commun, 11, 2020
8BMQ
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BU of 8bmq by Molmil
Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs bound to AMP-PNP
Descriptor: Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT, ...
Authors:Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J.
Deposit date:2022-11-10
Release date:2023-08-02
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Expulsion mechanism of the substrate-translocating subunit in ECF transporters.
Nat Commun, 14, 2023
8BMR
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BU of 8bmr by Molmil
Cryo-EM structure of the wild-type solitary ECF module in MSP2N2 lipid nanodiscs in the ATPase open and nucleotide-free conformation
Descriptor: Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT
Authors:Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J.
Deposit date:2022-11-10
Release date:2023-08-02
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Expulsion mechanism of the substrate-translocating subunit in ECF transporters.
Nat Commun, 14, 2023
8BMS
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BU of 8bms by Molmil
Cryo-EM structure of the mutant solitary ECF module 2EQ in MSP2N2 lipid nanodiscs in the ATPase closed and ATP-bound conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, ...
Authors:Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J.
Deposit date:2022-11-10
Release date:2023-08-02
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Expulsion mechanism of the substrate-translocating subunit in ECF transporters.
Nat Commun, 14, 2023
8BMP
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BU of 8bmp by Molmil
Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs bound to ATP and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Energy-coupling factor transporter ATP-binding protein EcfA1, ...
Authors:Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J.
Deposit date:2022-11-10
Release date:2023-08-02
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Expulsion mechanism of the substrate-translocating subunit in ECF transporters.
Nat Commun, 14, 2023
8PD8
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BU of 8pd8 by Molmil
cAMP-bound SpSLC9C1 in lipid nanodiscs, dimer
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Sperm-specific sodium proton exchanger
Authors:Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C.
Deposit date:2023-06-12
Release date:2023-11-08
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
8PD3
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BU of 8pd3 by Molmil
Ligand-free SpSLC9C1 in lipid nanodiscs, protomer state 2
Descriptor: Sperm-specific sodium proton exchanger
Authors:Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C.
Deposit date:2023-06-11
Release date:2023-11-08
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
8PCZ
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BU of 8pcz by Molmil
Ligand-free SpSLC9C1 in lipid nanodiscs, dimer
Descriptor: Sperm-specific sodium proton exchanger
Authors:Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C.
Deposit date:2023-06-11
Release date:2023-11-08
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
8PD2
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BU of 8pd2 by Molmil
Ligand-free SpSLC9C1 in lipid nanodiscs, protomer state 1
Descriptor: Sperm-specific sodium proton exchanger
Authors:Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C.
Deposit date:2023-06-11
Release date:2023-11-08
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
8PD7
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BU of 8pd7 by Molmil
Ligand-free SpSLC9C1 in lipid nanodiscs, protomer state 4
Descriptor: Sperm-specific sodium proton exchanger
Authors:Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C.
Deposit date:2023-06-11
Release date:2023-11-08
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
8PD5
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BU of 8pd5 by Molmil
Ligand-free SpSLC9C1 in lipid nanodiscs, protomer state 3
Descriptor: Sperm-specific sodium proton exchanger
Authors:Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C.
Deposit date:2023-06-11
Release date:2023-11-08
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
8PDU
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BU of 8pdu by Molmil
cGMP-bound SpSLC9C1 in lipid nanodiscs, dimer
Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, Sperm-specific sodium proton exchanger
Authors:Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C.
Deposit date:2023-06-12
Release date:2023-11-08
Last modified:2025-07-09
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023

 

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