7P79

SARS-CoV-2 spike protein in complex with sybodyb#15 in a 1up/1up-out/1down conformation.

Summary for 7P79

• Entry DOI: 10.2210/pdb7p79/pdb
• Related: 7P77 7P78 7P7A 7P7B
• EMDB information: 12084
• Descriptor: Spike glycoprotein, sybody#15, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: sars-cov-2 spike protein sybody, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 6
• Total formula weight: 476513.26

Authors

Walter, J.D.,Hutter, C.A.J.,Garaeva, A.A.,Scherer, M.,Zimmermann, I.,Wyss, M.,Rheinberger, J.,Ruedin, Y.,Earp, J.C.,Egloff, P.,Sorgenfrei, M.,Huerlimann, L.M.,Gonda, I.,Meier, G.,Remm, S.,Thavarasah, S.,Zimmer, G.,Slotboom, D.J.,Paulino, C.,Plattet, P.,Seeger, M.A. (deposition date: 2021-07-19, release date: 2021-08-04, Last modification date: 2022-04-20)

• Primary citation: Walter, J.D.,Scherer, M.,Hutter, C.A.J.,Garaeva, A.A.,Zimmermann, I.,Wyss, M.,Rheinberger, J.,Ruedin, Y.,Earp, J.C.,Egloff, P.,Sorgenfrei, M.,Hurlimann, L.M.,Gonda, I.,Meier, G.,Remm, S.,Thavarasah, S.,van Geest, G.,Bruggmann, R.,Zimmer, G.,Slotboom, D.J.,Paulino, C.,Plattet, P.,Seeger, M.A.; Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance.; Embo Rep., 23:e54199-e54199, 2022; PubMed: 35253970; DOI: 10.15252/embr.202154199

Experimental method

ELECTRON MICROSCOPY (4 Å)