7P7B

SARS-CoV-2 spike protein in complex with sybody no68 in a 1up/2down conformation

Summary for 7P7B

Entry DOI	10.2210/pdb7p7b/pdb
EMDB information	12086
Descriptor	Spike glycoprotein (1 entity in total)
Functional Keywords	sars-cov-2 spike protein sybody, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
Total number of polymer chains	3
Total formula weight	427282.31
Authors	Walter, J.D.,Hutter, C.A.J.,Garaeva, A.A.,Scherer, M.,Zimmermann, I.,Wyss, M.,Rheinberger, J.,Ruedin, Y.,Earp, J.C.,Egloff, P.,Sorgenfrei, M.,Huerlimann, L.M.,Gonda, I.,Meier, G.,Remm, S.,Thavarasah, S.,Zimmer, G.,Slotboom, D.J.,Paulino, C.,Plattet, P.,Seeger, M.A. (deposition date: 2021-07-19, release date: 2021-08-04, Last modification date: 2022-04-20)
Primary citation	Walter, J.D.,Scherer, M.,Hutter, C.A.J.,Garaeva, A.A.,Zimmermann, I.,Wyss, M.,Rheinberger, J.,Ruedin, Y.,Earp, J.C.,Egloff, P.,Sorgenfrei, M.,Hurlimann, L.M.,Gonda, I.,Meier, G.,Remm, S.,Thavarasah, S.,van Geest, G.,Bruggmann, R.,Zimmer, G.,Slotboom, D.J.,Paulino, C.,Plattet, P.,Seeger, M.A. Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance. Embo Rep., 23:e54199-e54199, 2022 Cited by PubMed: 35253970 DOI: 10.15252/embr.202154199 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.13 Å)

Structure validation