7P78

SARS-CoV-2 spike protein in complex with sybody#15 and sybody#68 in a 1up/1up-out/1down conformation

Summary for 7P78

• Entry DOI: 10.2210/pdb7p78/pdb
• Related: 7P77 7P79 7P7A 7P7B
• EMDB information: 12083
• Descriptor: Spike glycoprotein, sybody#15, sybody#68, ... (7 entities in total)
• Functional Keywords: sars-cov-2 spike protein sybody, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 8
• Total formula weight: 503528.13

Authors

Walter, J.D.,Hutter, C.A.J.,Garaeva, A.A.,Scherer, M.,Zimmermann, I.,Wyss, M.,Rheinberger, J.,Ruedin, Y.,Earp, J.C.,Egloff, P.,Sorgenfrei, M.,Huerlimann, L.M.,Gonda, I.,Meier, G.,Remm, S.,Thavarasah, S.,Zimmer, G.,Slotboom, D.J.,Paulino, C.,Plattet, P.,Seeger, M.A. (deposition date: 2021-07-19, release date: 2021-08-04, Last modification date: 2022-04-20)

• Primary citation: Walter, J.D.,Scherer, M.,Hutter, C.A.J.,Garaeva, A.A.,Zimmermann, I.,Wyss, M.,Rheinberger, J.,Ruedin, Y.,Earp, J.C.,Egloff, P.,Sorgenfrei, M.,Hurlimann, L.M.,Gonda, I.,Meier, G.,Remm, S.,Thavarasah, S.,van Geest, G.,Bruggmann, R.,Zimmer, G.,Slotboom, D.J.,Paulino, C.,Plattet, P.,Seeger, M.A.; Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance.; Embo Rep., 23:e54199-e54199, 2022; PubMed: 35253970; DOI: 10.15252/embr.202154199

Experimental method

ELECTRON MICROSCOPY (3.32 Å)