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8GAF
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BU of 8gaf by Molmil
Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications
Descriptor: Cas11, Cas5, Cas7, ...
Authors:Hu, C, Nam, K.H, Ke, A.
Deposit date:2023-02-22
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Mol.Cell, 84, 2024
8GAM
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BU of 8gam by Molmil
Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications
Descriptor: Cas11, Cas5, Cas7, ...
Authors:Hu, C, Nam, K.H, Ke, A.
Deposit date:2023-02-23
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Mol.Cell, 84, 2024
8GAN
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BU of 8gan by Molmil
Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications
Descriptor: Cas11, Cas5, Cas7, ...
Authors:Hu, C, Nam, K.H, Ke, A.
Deposit date:2023-02-23
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Mol.Cell, 84, 2024
7TR6
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BU of 7tr6 by Molmil
Cascade complex from type I-A CRISPR-Cas system
Descriptor: Cas11a, Cas5a, Cas7a, ...
Authors:Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A.
Deposit date:2022-01-28
Release date:2022-08-10
Last modified:2022-08-17
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools.
Mol.Cell, 82, 2022
7TR8
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BU of 7tr8 by Molmil
Cascade complex from type I-A CRISPR-Cas system
Descriptor: CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ...
Authors:Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A.
Deposit date:2022-01-28
Release date:2022-08-10
Last modified:2022-08-17
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools.
Mol.Cell, 82, 2022
7TRA
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BU of 7tra by Molmil
Cascade complex from type I-A CRISPR-Cas system
Descriptor: CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ...
Authors:Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A.
Deposit date:2022-01-28
Release date:2022-08-10
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools.
Mol.Cell, 82, 2022
7TR9
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BU of 7tr9 by Molmil
Cascade complex from type I-A CRISPR-Cas system
Descriptor: CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ...
Authors:Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A.
Deposit date:2022-01-28
Release date:2022-08-10
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools.
Mol.Cell, 82, 2022
5Y8Q
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BU of 5y8q by Molmil
ZsYellow at pH 8.0
Descriptor: GFP-like fluorescent chromoprotein FP538
Authors:Bae, J.E, Kim, I.J, Nam, K.H.
Deposit date:2017-08-21
Release date:2017-09-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Disruption of the hydrogen bonding network determines the pH-induced non-fluorescent state of the fluorescent protein ZsYellow by protonation of Glu221.
Biochem. Biophys. Res. Commun., 493, 2017
5Y4J
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BU of 5y4j by Molmil
Crystal structure of glucose isomerase in complex with xylitol inhibitor in one metal binding mode
Descriptor: MAGNESIUM ION, Xylitol, Xylose isomerase
Authors:Bae, J.E, Kim, I.J, Nam, K.H.
Deposit date:2017-08-03
Release date:2017-09-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of glucose isomerase in complex with xylitol inhibitor in one metal binding mode
Biochem. Biophys. Res. Commun., 493, 2017
5Y4I
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BU of 5y4i by Molmil
Crystal structure of glucose isomerase in complex with glycerol in one metal binding mode
Descriptor: ACETATE ION, GLYCEROL, MAGNESIUM ION, ...
Authors:Bae, J.E, Kim, I.J, Nam, K.H.
Deposit date:2017-08-03
Release date:2017-09-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Crystal structure of glucose isomerase in complex with xylitol inhibitor in one metal binding mode
Biochem. Biophys. Res. Commun., 493, 2017
5Z6V
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BU of 5z6v by Molmil
Crystal structure of a substrate-binding protein from Rhodothermus marinus
Descriptor: ABC-type uncharacterized transport system periplasmic component-like protein
Authors:Bae, J.E, Kim, I.J, Nam, K.H.
Deposit date:2018-01-25
Release date:2018-05-30
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Crystal structure of a substrate-binding protein from Rhodothermus marinus reveals a single alpha / beta-domain.
Biochem. Biophys. Res. Commun., 497, 2018
6AA7
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BU of 6aa7 by Molmil
Fluorescent protein from Acropora digitifera
Descriptor: Fluorescent protein
Authors:Kim, S.E, Hwang, K.Y, Nam, K.H.
Deposit date:2018-07-17
Release date:2018-08-22
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Spectral and structural analysis of a red fluorescent protein from Acropora digitifera.
Protein Sci., 28, 2019
5Y8R
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BU of 5y8r by Molmil
ZsYellow at pH 3.5
Descriptor: GFP-like fluorescent chromoprotein FP538
Authors:Bae, J.E, Kim, I.J, Nam, K.H.
Deposit date:2017-08-21
Release date:2017-09-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Disruption of the hydrogen bonding network determines the pH-induced non-fluorescent state of the fluorescent protein ZsYellow by protonation of Glu221.
Biochem. Biophys. Res. Commun., 493, 2017
3V9A
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BU of 3v9a by Molmil
Crystal structure of Esterase/Lipase from uncultured bacterium
Descriptor: Esterase/lipase, SULFATE ION
Authors:Kim, I.J, Nam, K.H.
Deposit date:2011-12-24
Release date:2012-02-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Crystal structure of Esterase/Lipase from uncultured bacterium
To be Published
4QQZ
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BU of 4qqz by Molmil
Crystal structure of T. fusca Cas3-AMPPNP
Descriptor: CRISPR-associated helicase, Cas3 family, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
Authors:Ke, A, Huo, Y, Nam, K.H.
Deposit date:2014-06-30
Release date:2014-08-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
4QQY
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BU of 4qqy by Molmil
Crystal structure of T. fusca Cas3-ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CRISPR-associated helicase, Cas3 family, ...
Authors:Ke, A, Huo, Y, Nam, K.H.
Deposit date:2014-06-30
Release date:2014-08-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
4QQX
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BU of 4qqx by Molmil
Crystal structure of T. fusca Cas3-ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CRISPR-associated helicase, Cas3 family, ...
Authors:Ke, A, Huo, Y, Nam, K.H.
Deposit date:2014-06-30
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
4QQW
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BU of 4qqw by Molmil
Crystal structure of T. fusca Cas3
Descriptor: CRISPR-associated helicase, Cas3 family, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
Authors:Ke, A, Huo, Y, Nam, K.H.
Deposit date:2014-06-30
Release date:2014-08-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.664 Å)
Cite:Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation.
Nat.Struct.Mol.Biol., 21, 2014
7YGF
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BU of 7ygf by Molmil
Crystal structure of YggS from Fusobacterium nucleatum
Descriptor: Pyridoxal phosphate homeostasis protein, SULFATE ION
Authors:He, S.R, Chan, Y.Y, Wang, L.L, Bai, X, Bu, T.T, Zhang, J, Xu, Y.B.
Deposit date:2022-07-11
Release date:2022-10-12
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structural and Functional Analysis of the Pyridoxal Phosphate Homeostasis Protein YggS from Fusobacterium nucleatum.
Molecules, 27, 2022
7MID
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BU of 7mid by Molmil
Sub-complex of Cas4-Cas1-Cas2 bound PAM containing DNA
Descriptor: CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (33-MER), ...
Authors:Hu, C.Y, Ke, A.K.
Deposit date:2021-04-16
Release date:2021-11-17
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
7MI4
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BU of 7mi4 by Molmil
Symmetrical PAM-PAM prespacer bound Cas4/Cas1/Cas2 complex
Descriptor: CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (35-MER), ...
Authors:Hu, C.Y, Ke, A.K.
Deposit date:2021-04-16
Release date:2021-11-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
7MI5
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BU of 7mi5 by Molmil
Asymmetrical PAM-Non PAM prespacer bound Cas4/Cas1/Cas2 complex
Descriptor: CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (26-MER), ...
Authors:Hu, C.Y, Ke, A.K.
Deposit date:2021-04-16
Release date:2021-11-17
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
7MI9
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BU of 7mi9 by Molmil
Full integration complex of Cas1/Cas2 from Cas4-containing system
Descriptor: CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (5'-D(P*CP*GP*GP*AP*AP*AP*AP*GP*AP*GP*CP*C)-3'), ...
Authors:Hu, C.Y, Ke, A.K.
Deposit date:2021-04-16
Release date:2021-11-17
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
7MIB
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BU of 7mib by Molmil
Half integration complex of Cas4/Cas1/Cas2 with Cas4 still on the Non-PAM side
Descriptor: CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (31-MER), ...
Authors:Hu, C.Y, Ke, A.K.
Deposit date:2021-04-16
Release date:2021-11-17
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Nature, 598, 2021
2OHE
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BU of 2ohe by Molmil
Structural and mutational analysis of tRNA-Intron splicing endonuclease from Thermoplasma acidophilum DSM 1728
Descriptor: tRNA-splicing endonuclease
Authors:Kim, Y.K, Mizutani, K, Rhee, K.H, Lee, W.H, Park, S.Y, Hwang, K.Y.
Deposit date:2007-01-10
Release date:2007-11-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and Mutational Analysis of tRNA Intron-Splicing Endonuclease from Thermoplasma acidophilum DSM 1728: Catalytic Mechanism of tRNA Intron-Splicing Endonucleases
J.Bacteriol., 189, 2007

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