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5JVX
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BU of 5jvx by Molmil
X-ray structure of the adduct formed in the reaction between thaumatin and a gold carbene compound
Descriptor: (1-butyl-3-methyl-1,3-dihydro-2H-imidazol-2-ylidene)(chloro)gold, CHLORIDE ION, L(+)-TARTARIC ACID, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2016-05-11
Release date:2016-07-13
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:First Crystal Structure for a Gold Carbene-Protein Adduct.
Bioconjug.Chem., 27, 2016
6SET
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BU of 6set by Molmil
X-ray structure of the gold/lysozyme adduct formed upon 3 days exposure of protein crystals to compound 1
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
Authors:Ferraro, G, Giorgio, A, Merlino, A.
Deposit date:2019-07-30
Release date:2019-09-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Protein-mediated disproportionation of Au(i): insights from the structures of adducts of Au(iii) compounds bearing N,N-pyridylbenzimidazole derivatives with lysozyme.
Dalton Trans, 48, 2019
6SEU
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BU of 6seu by Molmil
X-ray structure of the gold/lysozyme adduct formed upon 21h exposure of protein crystals to compound 2
Descriptor: 1,2-ETHANEDIOL, GOLD ION, Lysozyme C, ...
Authors:Ferraro, G, Giorgio, A, Merlino, A.
Deposit date:2019-07-30
Release date:2019-09-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Protein-mediated disproportionation of Au(i): insights from the structures of adducts of Au(iii) compounds bearing N,N-pyridylbenzimidazole derivatives with lysozyme.
Dalton Trans, 48, 2019
6SEW
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BU of 6sew by Molmil
X-ray structure of the gold/lysozyme adduct formed upon 24h exposure of protein crystals to compound 2
Descriptor: 1,2-ETHANEDIOL, GOLD ION, Lysozyme C, ...
Authors:Ferraro, G, Giorgio, A, Merlino, A.
Deposit date:2019-07-30
Release date:2019-09-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Protein-mediated disproportionation of Au(i): insights from the structures of adducts of Au(iii) compounds bearing N,N-pyridylbenzimidazole derivatives with lysozyme.
Dalton Trans, 48, 2019
6SEX
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BU of 6sex by Molmil
X-ray structure of the gold/lysozyme adduct formed upon 21h exposure of protein crystals to compound 1
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, DIMETHYL SULFOXIDE, ...
Authors:Ferraro, G, Giorgio, A, Merlino, A.
Deposit date:2019-07-30
Release date:2019-09-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Protein-mediated disproportionation of Au(i): insights from the structures of adducts of Au(iii) compounds bearing N,N-pyridylbenzimidazole derivatives with lysozyme.
Dalton Trans, 48, 2019
6SEZ
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BU of 6sez by Molmil
X-ray structure of the gold/lysozyme adduct formed upon 24h exposure of protein crystals to compound 1
Descriptor: 1,2-ETHANEDIOL, GOLD ION, Lysozyme C, ...
Authors:Ferraro, G, Giorgio, A, Merlino, A.
Deposit date:2019-07-30
Release date:2019-09-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Protein-mediated disproportionation of Au(i): insights from the structures of adducts of Au(iii) compounds bearing N,N-pyridylbenzimidazole derivatives with lysozyme.
Dalton Trans, 48, 2019
5L4R
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BU of 5l4r by Molmil
X-ray structure of the adduct between thaumatin and cisplatin
Descriptor: Cisplatin, GLYCEROL, L(+)-TARTARIC ACID, ...
Authors:Russo Krauss, I, Ferraro, G, Merlino, A.
Deposit date:2016-05-26
Release date:2016-12-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Cisplatin-Protein Interactions: Unexpected Drug Binding to N-Terminal Amine and Lysine Side Chains.
Inorg.Chem., 55, 2016
5JLG
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BU of 5jlg by Molmil
The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and compound I, a piano-stool organometallic Ru(II) arene compound containing an O,S-chelating ligand
Descriptor: DIMETHYL SULFOXIDE, RUTHENIUM ION, Ribonuclease pancreatic, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2016-04-27
Release date:2016-08-03
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Unusual mode of protein binding by a cytotoxic pi-arene ruthenium(ii) piano-stool compound containing an O,S-chelating ligand.
Dalton Trans, 45, 2016
6RP5
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BU of 6rp5 by Molmil
Crystal structure of monocarboxylated hemoglobin from the sub-Antarctic fish Eleginops maclovinus
Descriptor: CARBON MONOXIDE, DITHIONITE, Hemoglobin subunit alpha 1, ...
Authors:Balasco, N, Vitagliano, L, Merlino, A, Verde, C, Mazzarella, L, Vergara, A.
Deposit date:2019-05-13
Release date:2019-12-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:The unique structural features of carbonmonoxy hemoglobin from the sub-Antarctic fish Eleginops maclovinus.
Sci Rep, 9, 2019
5IHG
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BU of 5ihg by Molmil
The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme a compound I, a platin(II) compound containing a O, S bidentate ligand
Descriptor: CHLORIDE ION, DIMETHYL SULFOXIDE, Lysozyme C, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2016-02-29
Release date:2016-12-07
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Platinum(ii) O,S complexes as potential metallodrugs against Cisplatin resistance.
Dalton Trans, 45, 2016
5II3
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BU of 5ii3 by Molmil
The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme and compound 3, a platin(II) compound containing a O, S bidentate ligand
Descriptor: CHLORIDE ION, DIMETHYL SULFOXIDE, Lysozyme C, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2016-03-01
Release date:2016-12-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Platinum(ii) O,S complexes as potential metallodrugs against Cisplatin resistance.
Dalton Trans, 45, 2016
8BRC
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BU of 8brc by Molmil
Crystal structure of the adduct between human serum transferrin and cisplatin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIA, FE (III) ION, ...
Authors:Troisi, R, Galardo, F, Ferraro, G, Sica, F, Merlino, A.
Deposit date:2022-11-22
Release date:2023-01-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Cisplatin Binding to Human Serum Transferrin: A Crystallographic Study.
Inorg.Chem., 62, 2023
8Q0R
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BU of 8q0r by Molmil
X-ray structure of MNEI mutant Mut9 (E23A, C41A, Y65R, S76Y)
Descriptor: ACETATE ION, Monellin chain B,Monellin chain A, SULFATE ION
Authors:Ferraro, G, Merlino, A, Lucignano, R, Picone, D.
Deposit date:2023-07-29
Release date:2024-02-07
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural insights and aggregation propensity of a super-stable monellin mutant: A new potential building block for protein-based nanostructured materials.
Int.J.Biol.Macromol., 254, 2024
8Q0S
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BU of 8q0s by Molmil
X-ray structure of the single chain monellin derivative MNEI
Descriptor: ACETATE ION, GLYCEROL, Monellin chain B,Monellin chain A, ...
Authors:Ferraro, G, Merlino, A, Lucignano, R, Picone, D.
Deposit date:2023-07-29
Release date:2024-02-07
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Structural insights and aggregation propensity of a super-stable monellin mutant: A new potential building block for protein-based nanostructured materials.
Int.J.Biol.Macromol., 254, 2024
6ZS8
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BU of 6zs8 by Molmil
X-ray structure of the adduct formed upon treating lysozyme with an aged solution of arsenoplatin-1
Descriptor: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Lysozyme, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2020-07-15
Release date:2020-12-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.153 Å)
Cite:The first step of arsenoplatin-1 aggregation in solution unveiled by solving the crystal structure of its protein adduct.
Dalton Trans, 50, 2021
7BD7
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BU of 7bd7 by Molmil
X-ray structure of Arsenoplatin-1-encapsulated horse spleen ferritin
Descriptor: CADMIUM ION, CHLORIDE ION, Ferritin light chain, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2020-12-21
Release date:2021-03-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Arsenoplatin-Ferritin Nanocage: Structure and Cytotoxicity.
Int J Mol Sci, 22, 2021
8BOV
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BU of 8bov by Molmil
X-ray structure of the adduct formed upon reaction of the five-coordinate Pt(II) complex, 1-Me,Me, with HEWL at pH 7.5
Descriptor: 1-[1,3-dimethyl-4-(1~{H}-1,2,3-triazol-5-yl)imidazol-1-ium-2-yl]-1,2',11'-trimethyl-spiro[1$l^{6}-platinacycloprop-2-ene-1,15'-1,12-diaza-15$l^{6}-platinatetracyclo[10.2.1.0^{5,14}.0^{8,13}]pentadeca-2,4,6,8,10,13-hexaene], 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ...
Authors:Ferraro, G, Tito, G, Merlino, A.
Deposit date:2022-11-15
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Impact of Hydrophobic Chains in Five-Coordinate Glucoconjugate Pt(II) Anticancer Agents.
Int J Mol Sci, 24, 2023
7QHR
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BU of 7qhr by Molmil
Unexpected imidazole coordination to dirhodium tetraacetate complex in a protein environment: insights from X-ray crystallography and quantum chemistry
Descriptor: Ribonuclease pancreatic, cis-mi2-acetato-(O, O')-N-imidazyl-pentaaqua-dirhodium(II, ...
Authors:Loreto, D, Merlino, A.
Deposit date:2021-12-13
Release date:2022-06-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Unexpected Imidazole Coordination to the Dirhodium Center in a Protein Environment: Insights from X-ray Crystallography and Quantum Chemistry.
Inorg.Chem., 61, 2022
7PNI
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BU of 7pni by Molmil
X-ray structure of the adduct formed upon reaction of Pt(II) complex 2c with ribonuclease A
Descriptor: PLATINUM (II) ION, Ribonuclease pancreatic
Authors:Ferraro, G, Merlino, A.
Deposit date:2021-09-07
Release date:2021-10-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Reactions with Proteins of Three Novel Anticancer Platinum(II) Complexes Bearing N-Heterocyclic Ligands.
Int J Mol Sci, 22, 2021
7PNH
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BU of 7pnh by Molmil
X-ray structure of the adduct formed upon reaction of Pt(II) complex 2c with lysozyme
Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, IMIDAZOLE, ...
Authors:Ferraro, G, Merlino, A.
Deposit date:2021-09-07
Release date:2021-10-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Reactions with Proteins of Three Novel Anticancer Platinum(II) Complexes Bearing N-Heterocyclic Ligands.
Int J Mol Sci, 22, 2021
8BOY
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BU of 8boy by Molmil
X-ray structure of the adduct formed upon reaction of the five-coordinate Pt(II) complex, 1-Me,Me, with HEWL at pH 4.0
Descriptor: 1-[1,3-dimethyl-4-(1~{H}-1,2,3-triazol-5-yl)imidazol-1-ium-2-yl]-1,2',11'-trimethyl-spiro[1$l^{6}-platinacycloprop-2-ene-1,15'-1,12-diaza-15$l^{6}-platinatetracyclo[10.2.1.0^{5,14}.0^{8,13}]pentadeca-2,4,6,8,10,13-hexaene], Lysozyme C, NITRATE ION, ...
Authors:Ferraro, G, Tito, G, Merlino, A.
Deposit date:2022-11-15
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Impact of Hydrophobic Chains in Five-Coordinate Glucoconjugate Pt(II) Anticancer Agents.
Int J Mol Sci, 24, 2023
4J1B
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BU of 4j1b by Molmil
X-ray structure of the adduct between hen egg white lysozyme and AziRu (black crystal)
Descriptor: CHLORIDE ION, Lysozyme C, RUTHENIUM ION, ...
Authors:Vergara, A, Merlino, A.
Deposit date:2013-02-01
Release date:2013-04-03
Last modified:2013-05-08
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Interaction of Anticancer Ruthenium Compounds with Proteins: High-Resolution X-ray Structures and Raman Microscopy Studies of the Adduct between Hen Egg White Lysozyme and AziRu.
Inorg.Chem., 52, 2013
4J1A
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BU of 4j1a by Molmil
X-ray structure of the adduct between hen egg white lysozyme and AziRu (green crystal)
Descriptor: CHLORIDE ION, Lysozyme C, RUTHENIUM ION, ...
Authors:Vergara, A, Merlino, A.
Deposit date:2013-02-01
Release date:2013-04-03
Last modified:2013-05-08
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Interaction of Anticancer Ruthenium Compounds with Proteins: High-Resolution X-ray Structures and Raman Microscopy Studies of the Adduct between Hen Egg White Lysozyme and AziRu.
Inorg.Chem., 52, 2013
4KXH
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BU of 4kxh by Molmil
The X-ray crystal structure of a dimeric variant of human pancreatic ribonuclease
Descriptor: CHLORIDE ION, Ribonuclease pancreatic, SODIUM ION, ...
Authors:Pica, A, Merlino, A, Mazzarella, L, Sica, F.
Deposit date:2013-05-26
Release date:2013-10-02
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase.
Acta Crystallogr.,Sect.D, 69, 2013
4L55
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BU of 4l55 by Molmil
X-ray structure of the adduct between bovine pancreatic ribonuclease and AziRu
Descriptor: RUTHENIUM ION, Ribonuclease pancreatic
Authors:Vergara, A, Russo Krauss, I, Merlino, A.
Deposit date:2013-06-10
Release date:2014-01-29
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Investigating the ruthenium metalation of proteins: X-ray structure and Raman microspectroscopy of the complex between RNase A and AziRu.
Inorg.Chem., 52, 2013

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