4J1B

X-ray structure of the adduct between hen egg white lysozyme and AziRu (black crystal)

Summary for 4J1B

Entry DOI	10.2210/pdb4j1b/pdb
Related	4J1A
Descriptor	Lysozyme C, CHLORIDE ION, SODIUM ION, ... (5 entities in total)
Functional Keywords	c-type lysozyme/alpha-lactalbumin family, hydrolase
Biological source	Gallus gallus (bantam,chickens)
Cellular location	Secreted: P00698
Total number of polymer chains	1
Total formula weight	14526.13
Authors	Vergara, A.,Merlino, A. (deposition date: 2013-02-01, release date: 2013-04-03, Last modification date: 2013-05-08)
Primary citation	Vergara, A.,D'Errico, G.,Montesarchio, D.,Mangiapia, G.,Paduano, L.,Merlino, A. Interaction of Anticancer Ruthenium Compounds with Proteins: High-Resolution X-ray Structures and Raman Microscopy Studies of the Adduct between Hen Egg White Lysozyme and AziRu. Inorg.Chem., 52:4157-4159, 2013 Cited by PubMed Abstract: The binding properties of AziRu, a ruthenium(III) complex with high antiproliferative activity, toward a hen egg white lysozyme have been investigated by X-ray crystallography and Raman microscopy. The data provide clear evidence on the mechanism of AziRu-protein adduct formation and of ligand exchange in the crystal state. PubMed: 23517183 DOI: 10.1021/ic4004142 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.66 Å)

Structure validation