8SR7
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![BU of 8sr7 by Molmil](/molmil-images/mine/8sr7) | Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, Adenosine monophosphate, and Ribose-5-phosphate | Descriptor: | 5-O-phosphono-beta-D-ribofuranose, ADENOSINE MONOPHOSPHATE, CHOLESTEROL, ... | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | Deposit date: | 2023-05-05 | Release date: | 2024-05-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (1.97 Å) | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. Nat.Struct.Mol.Biol., 2024
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8SRB
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![BU of 8srb by Molmil](/molmil-images/mine/8srb) | Cryo-EM structure of TRPM2 chanzyme in the presence of EDTA and ADP-ribose | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CHOLESTEROL, TRPM2 chanzyme | Authors: | Huang, Y, Kumar, S, Lu, W, Du, J. | Deposit date: | 2023-05-05 | Release date: | 2024-05-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.82 Å) | Cite: | Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution. Nat.Struct.Mol.Biol., 2024
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8TG1
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![BU of 8tg1 by Molmil](/molmil-images/mine/8tg1) | Caldicellulosiruptor saccharolyticus periplasmic urea-binding protein | Descriptor: | BROMIDE ION, Extracellular ligand-binding receptor, UREA | Authors: | Allert, M.J, Kumar, S, Wang, Y, Beese, L.S, Hellinga, H.W. | Deposit date: | 2023-07-12 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.097 Å) | Cite: | Structure-based functional analysis reveals multiple roles and widespread use of urea-binding proteins in nitrogen metabolism To Be Published
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8C3I
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![BU of 8c3i by Molmil](/molmil-images/mine/8c3i) | Dark state of PAS-GAF fragment from Deinococcus radiodurans phytochrome | Descriptor: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome | Authors: | Madan Kumar, S, Sebastian, W. | Deposit date: | 2022-12-24 | Release date: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Dark state of PAS-GAF fragment from Deinococcus radiodurans phytochrome To Be Published
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3BC3
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![BU of 3bc3 by Molmil](/molmil-images/mine/3bc3) | Exploring inhibitor binding at the S subsites of cathepsin L | Descriptor: | Cathepsin L heavy and light chains, S-benzyl-N-(biphenyl-4-ylacetyl)-L-cysteinyl-N~5~-(diaminomethyl)-D-ornithyl-N-(2-phenylethyl)-L-tyrosinamide | Authors: | Chowdhury, S.F, Joseph, L, Kumar, S, Tulsidas, S.R, Bhat, S, Ziomek, E, Nard, R.M, Sivaraman, J, Purisima, E.O. | Deposit date: | 2007-11-12 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Exploring inhibitor binding at the S' subsites of cathepsin L J.Med.Chem., 51, 2008
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4QDM
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![BU of 4qdm by Molmil](/molmil-images/mine/4qdm) | Crystal structure of N-terminal mutant (V1L) of an alkali thermostable GH10 xylanase from Bacillus sp. NG-27 | Descriptor: | Alkaline thermostable endoxylanase, GLYCEROL, MAGNESIUM ION, ... | Authors: | Mahanta, P, Bhardwaj, A, Reddy, V.S, Ramakumar, S. | Deposit date: | 2014-05-14 | Release date: | 2015-05-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.964 Å) | Cite: | Structural insights into N-terminal to C-terminal interactions and implications for thermostability of a (beta/alpha)8-triosephosphate isomerase barrel enzyme Febs J., 282, 2015
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4QCE
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![BU of 4qce by Molmil](/molmil-images/mine/4qce) | Crystal structure of recombinant alkali thermostable GH10 xylanase from Bacillus sp. NG-27 | Descriptor: | Alkaline thermostable endoxylanase, MAGNESIUM ION, SODIUM ION | Authors: | Mahanta, P, Bhardwaj, A, Reddy, V.S, Ramakumar, S. | Deposit date: | 2014-05-11 | Release date: | 2015-05-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Structural insights into N-terminal to C-terminal interactions and implications for thermostability of a (beta/alpha)8-triosephosphate isomerase barrel enzyme Febs J., 282, 2015
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4QCF
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![BU of 4qcf by Molmil](/molmil-images/mine/4qcf) | Crystal structure of N-terminal mutant (V1A) of an alkali thermostable GH10 xylanase from Bacillus sp. NG-27 | Descriptor: | Alkaline thermostable endoxylanase, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Mahanta, P, Bhardwaj, A, Reddy, V.S, Ramakumar, S. | Deposit date: | 2014-05-11 | Release date: | 2015-05-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Structural insights into N-terminal to C-terminal interactions and implications for thermostability of a (beta/alpha)8-triosephosphate isomerase barrel enzyme Febs J., 282, 2015
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3TW6
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![BU of 3tw6 by Molmil](/molmil-images/mine/3tw6) | Structure of Rhizobium etli pyruvate carboxylase T882A with the allosteric activator, acetyl coenzyme-A | Descriptor: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | St Maurice, M, Kumar, S, Lietzan, A.D. | Deposit date: | 2011-09-21 | Release date: | 2011-10-19 | Last modified: | 2011-12-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli. Biochemistry, 50, 2011
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3TW7
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![BU of 3tw7 by Molmil](/molmil-images/mine/3tw7) | Structure of Rhizobium etli pyruvate carboxylase T882A crystallized without acetyl coenzyme-A | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Pyruvate carboxylase protein, ... | Authors: | St Maurice, M, Kumar, S, Lietzan, A.D. | Deposit date: | 2011-09-21 | Release date: | 2011-10-12 | Last modified: | 2011-12-28 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli. Biochemistry, 50, 2011
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2FJ2
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![BU of 2fj2 by Molmil](/molmil-images/mine/2fj2) | Crystal Structure of Viral Macrophage Inflammatory Protein-II | Descriptor: | Viral macrophage inflammatory protein-II | Authors: | Li, Y, Liu, D, Cao, R, Kumar, S, Dong, C.Z, wilson, S.R, Gao, Y.G, Huang, Z. | Deposit date: | 2005-12-30 | Release date: | 2006-12-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of chemically synthesized vMIP-II. Proteins, 67, 2007
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2FHT
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![BU of 2fht by Molmil](/molmil-images/mine/2fht) | Crystal Structure of Viral Macrophage Inflammatory Protein-II | Descriptor: | Viral macrophage inflammatory protein-II | Authors: | Li, Y, Liu, D, Cao, R, Kumar, S, Dong, C.Z, wilson, S.R, Gao, Y.G, Huang, Z. | Deposit date: | 2005-12-27 | Release date: | 2006-12-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of chemically synthesized vMIP-II. Proteins, 67, 2007
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4N42
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![BU of 4n42 by Molmil](/molmil-images/mine/4n42) | Crystal structure of allergen protein scam1 from Scadoxus multiflorus | Descriptor: | PHOSPHATE ION, Xylanase and alpha-amylase inhibitor protein isoform III | Authors: | Singh, A, Kumar, S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2013-10-08 | Release date: | 2013-10-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of allergen protein scam1 from Scadoxus multiflorus To be published
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5VOE
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![BU of 5voe by Molmil](/molmil-images/mine/5voe) | DesGla-XaS195A Bound to Aptamer 11F7t | Descriptor: | Aptamer 11F7t (36-MER), CALCIUM ION, Coagulation factor X, ... | Authors: | Gunaratne, R, Kumar, S, Frederiksen, J.W, Stayrook, S, Lohrmann, J.L, Perry, K, Chabata, C.V, Thalji, N.K, Ho, M.D, Arepally, G, Camire, R.M, Krishnaswamy, S.K, Sullenger, B.A. | Deposit date: | 2017-05-02 | Release date: | 2018-06-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass. Nat. Biotechnol., 36, 2018
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4NZC
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![BU of 4nzc by Molmil](/molmil-images/mine/4nzc) | Crystal structure of Chitinase D from Serratia proteamaculans at 1.45 Angstrom resolution | Descriptor: | ACETATE ION, GLYCEROL, Glycoside hydrolase family 18 | Authors: | Madhuprakash, J, Singh, A, Kumar, S, Sinha, M, Kaur, P, Sharma, S, Podile, A.R, Singh, T.P. | Deposit date: | 2013-12-12 | Release date: | 2014-01-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of chitinase D from Serratia proteamaculans reveals the structural basis of its dual action of hydrolysis and transglycosylation Int J Biochem Mol Biol, 4, 2013
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7EWO
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![BU of 7ewo by Molmil](/molmil-images/mine/7ewo) | Crystal Structure of D67A, E68P double mutant of O-acetyl-L-serine sulfhydrylase from Haemophilus influenzae | Descriptor: | Cysteine synthase | Authors: | Rahisuddin, R, Ekka, M.K, Singh, A.K, Saini, N, Patel, M, Kumar, N, Kumaran, S. | Deposit date: | 2021-05-25 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of D67A, E68P double mutant of O-acetyl-L-serine sulfhydrylase from Haemophilus influenzae To Be Published
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5Y9R
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![BU of 5y9r by Molmil](/molmil-images/mine/5y9r) | |
2LXN
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![BU of 2lxn by Molmil](/molmil-images/mine/2lxn) | Solution NMR structure of glutamine amido transferase subunit of gaunosine monophosphate synthetase from Methanocaldococcus jannaschii | Descriptor: | GMP synthase [glutamine-hydrolyzing] subunit A | Authors: | Ali, R, Kumar, S, Balaram, H, Sarma, S.P. | Deposit date: | 2012-08-30 | Release date: | 2013-06-12 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | 1H, 13C, 15N assignment and secondary structure determination of glutamine amido transferase subunit of gaunosine monophosphate synthetase from Methanocaldococcus jannaschii Biomol.Nmr Assign., 6, 2012
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2Q6N
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![BU of 2q6n by Molmil](/molmil-images/mine/2q6n) | Structure of Cytochrome P450 2B4 with Bound 1-(4-cholorophenyl)imidazole | Descriptor: | 1-(4-CHLOROPHENYL)-1H-IMIDAZOLE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Zhao, Y, Sun, L, Muralidhara, B.K, Kumar, S, White, M.A, Stout, C.D, Halpert, J.R. | Deposit date: | 2007-06-05 | Release date: | 2007-11-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural and thermodynamic consequences of 1-(4-chlorophenyl)imidazole binding to cytochrome P450 2B4. Biochemistry, 46, 2007
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1VRZ
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![BU of 1vrz by Molmil](/molmil-images/mine/1vrz) | Helix turn helix motif | Descriptor: | ACETATE ION, DE NOVO DESIGNED 21 RESIDUE PEPTIDE | Authors: | Rudresh, Ramakumar, S, Ramagopal, U.A, Inai, Y, Sahal, D. | Deposit date: | 2005-10-14 | Release date: | 2005-11-01 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | De Novo Design and Characterization of a Helical Hairpin Eicosapeptide; Emergence of an Anion Receptor in the Linker Region. Structure, 12, 2004
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8JZA
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![BU of 8jza by Molmil](/molmil-images/mine/8jza) | Crystal structure of single domain antibody kt75 of human Thyroglobulin | Descriptor: | ACETATE ION, POTASSIUM ION, single domain antibody kt75 of human Thyroglobulin | Authors: | Mistry, H, Kumarasamy, J, Kumari, S, Kulkarni, S.P, Gupta, G.D. | Deposit date: | 2023-07-04 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Crystal structure of single domain antibody kt75 of human Thyroglobulin To Be Published
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4O8T
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![BU of 4o8t by Molmil](/molmil-images/mine/4o8t) | Structure of sortase A C207A mutant from Streptococcus pneumoniae | Descriptor: | GLYCEROL, Sortase | Authors: | Misra, A, Biswas, T, Das, S, Marathe, U, Roy, R.P, Ramakumar, S. | Deposit date: | 2013-12-30 | Release date: | 2015-01-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Structure of sortase A C207A mutant from Streptococcus pneumoniae To be Published
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5GO5
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![BU of 5go5 by Molmil](/molmil-images/mine/5go5) | Structure of sortase E from Streptomyces avermitilis | Descriptor: | GLYCINE, SULFATE ION, sortase | Authors: | Das, S, Pawale, V.S, Dadireddy, V, Roy, R.P, Ramakumar, S. | Deposit date: | 2016-07-26 | Release date: | 2017-03-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure and specificity of a new class of Ca2+-independent housekeeping sortase from Streptomyces avermitilis provide insights into its non-canonical substrate preference. J. Biol. Chem., 292, 2017
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7C35
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![BU of 7c35 by Molmil](/molmil-images/mine/7c35) | |
7DJQ
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![BU of 7djq by Molmil](/molmil-images/mine/7djq) | |