6V2Q
 
 | | HLA-B*57:03 presenting the peptide LSSPVTKSF | | Descriptor: | ACETATE ION, Beta-2-microglobulin, HLA-B alpha chain (B*5703GB), ... | | Authors: | Maclachlan, B, Rossjohn, J, Vivian, J.P. | | Deposit date: | 2019-11-25 | | Release date: | 2020-05-20 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6V3J
 | | KIR3DL1 in complex with HLA-B*57:03 presenting the peptide LSSPVTKSF | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA-B alpha chain (B*5703GB), ... | | Authors: | Maclachlan, B, Rossjohn, J, Vivian, J.P. | | Deposit date: | 2019-11-25 | | Release date: | 2020-05-20 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6V18
 | | immune receptor complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibrinogen beta, GLYCEROL, ... | | Authors: | Lim, J.J, Rossjohn, J. | | Deposit date: | 2019-11-20 | | Release date: | 2020-11-25 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR.
Sci Immunol, 6, 2021
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6V2P
 | | HLA-B*57:03 presenting the peptide ASLNLPAVSW | | Descriptor: | ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Maclachlan, B, Rossjohn, J, Vivian, J.P. | | Deposit date: | 2019-11-25 | | Release date: | 2020-05-20 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6VMX
 | | Structure of HD14 TCR in complex with HLA-B7 presenting an EBV epitope | | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Farenc, C, Rossjohn, J, Gras, S. | | Deposit date: | 2020-01-28 | | Release date: | 2020-07-29 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02-Expressing Individuals.
J Immunol., 205, 2020
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6X00
 | | Structure of DbNA(11) peptides bound to H-2Db MHC-I | | Descriptor: | Beta-2-microglobulin, Epitope from Neuraminidase Protein (NA-181-191), H-2 class I histocompatibility antigen, ... | | Authors: | Farenc, C, Rossjohn, J. | | Deposit date: | 2020-05-14 | | Release date: | 2020-09-16 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Overlapping Peptides Elicit Distinct CD8 + T Cell Responses following Influenza A Virus Infection.
J Immunol., 205, 2020
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6WZY
 | | Structure of DbNA(10) peptides bound to H-2Db MHC-I | | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Farenc, C, Rossjohn, J. | | Deposit date: | 2020-05-14 | | Release date: | 2020-09-16 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Overlapping Peptides Elicit Distinct CD8 + T Cell Responses following Influenza A Virus Infection.
J Immunol., 205, 2020
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3VFW
 | | crystal structure of HLA B*3508 LPEP-P10Ala, peptide mutant P10-ala | | Descriptor: | Beta-2-microglobulin, LPEP peptide from EBV, P10A, ... | | Authors: | Liu, Y.C, Rossjohn, J, Gras, S. | | Deposit date: | 2012-01-10 | | Release date: | 2012-02-22 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
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3VFV
 | | crystal structure of HLA B*3508 LPEP-P9Ala, peptide mutant P9-ala | | Descriptor: | Beta-2-microglobulin, LPEP peptide from EBV, P9A, ... | | Authors: | Liu, Y.C, Rossjohn, J, Gras, S. | | Deposit date: | 2012-01-10 | | Release date: | 2012-02-22 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
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2N24
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2NW3
 | | Crystal structure of HLA-B*3508 presenting EBV peptide EPLPQGQLTAY at 1.7A | | Descriptor: | Beta-2-microglobulin, EBV peptide EPLPQGQLTAY, HLA class I histocompatibility antigen, ... | | Authors: | Tynan, F.E, Reid, H.H, Rossjohn, J. | | Deposit date: | 2006-11-14 | | Release date: | 2007-02-27 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule
Nat.Immunol., 8, 2007
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2NW2
 | | Crystal structure of ELS4 TCR at 1.4A | | Descriptor: | ELS4 TCR alpha chain, ELS4 TCR beta chain | | Authors: | Tynan, F.E, Reid, H.H, Rossjohn, J. | | Deposit date: | 2006-11-14 | | Release date: | 2007-02-27 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule
Nat.Immunol., 8, 2007
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2NX5
 | | Crystal structure of ELS4 TCR bound to HLA-B*3501 presenting EBV peptide EPLPQGQLTAY at 1.7A | | Descriptor: | Beta-2-microglobulin, EBV peptide, EPLPQGQLTAY, ... | | Authors: | Tynan, F.E, Reid, H.H, Rossjohn, J. | | Deposit date: | 2006-11-16 | | Release date: | 2007-02-27 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule
Nat.Immunol., 8, 2007
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2NNA
 | | Structure of the MHC class II molecule HLA-DQ8 bound with a deamidated gluten peptide | | Descriptor: | MHC class II antigen, gluten peptide | | Authors: | Henderson, K.N, Tye-Din, J.A, Rossjohn, J, Anderson, R.P. | | Deposit date: | 2006-10-24 | | Release date: | 2007-09-04 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease
Immunity, 27, 2007
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7JYU
 | | Crystal Structure of HLA-A*2402 in complex with IYFSPIRVTF, an 10-mer epitope from Influenza B virus | | Descriptor: | Beta-2-microglobulin, MAGNESIUM ION, MHC class I antigen, ... | | Authors: | Nguyen, A.T, Szeto, C, Rossjohn, J, Gras, S. | | Deposit date: | 2020-09-01 | | Release date: | 2021-04-14 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph.
Nat Commun, 12, 2021
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7JYV
 | | Crystal Structure of HLA A*2402 in complex with YFSPIRVTF, an 9-mer influenza epitope | | Descriptor: | Beta-2-microglobulin, MAGNESIUM ION, MHC class I antigen, ... | | Authors: | Gras, S, Nguyen, A.T, Szeto, C, Rossjohn, J. | | Deposit date: | 2020-09-01 | | Release date: | 2021-04-14 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph.
Nat Commun, 12, 2021
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7JYW
 | | Crystal Structure of HLA A*2402 in complex with TYQWIIRNW, an 9-mer influenza epitope | | Descriptor: | Beta-2-microglobulin, CALCIUM ION, MHC class I antigen, ... | | Authors: | Gras, S, Nguyen, A.T, Szeto, C, Rossjohn, J. | | Deposit date: | 2020-09-01 | | Release date: | 2021-04-14 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph.
Nat Commun, 12, 2021
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7JYX
 | | Crystal Structure of HLA A*2402 in complex with TYQWIIRNWET, an 11-mer epitope from Influenza | | Descriptor: | Beta-2-microglobulin, MHC class I antigen, PB2 peptide from Influenza, ... | | Authors: | Gras, S, Nguyen, A.T, Szeto, C, Rossjohn, J. | | Deposit date: | 2020-09-01 | | Release date: | 2021-04-14 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph.
Nat Commun, 12, 2021
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3FQW
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3FQT
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3DX8
 | | Crystal Structure of B*4405 presenting a 10mer EBV epitope | | Descriptor: | Beta-2-microglobulin, EBV decapeptide epitope, GLYCEROL, ... | | Authors: | Archbold, J.K, Ely, L.K, Rossjohn, J. | | Deposit date: | 2008-07-23 | | Release date: | 2009-01-27 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.
J.Exp.Med., 206, 2009
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3DXA
 | | Crystal Structure of the DM1 TCR in complex with HLA-B*4405 and decamer EBV antigen | | Descriptor: | Beta-2-microglobulin, DM1 T cell receptor alpha chain, DM1 T cell receptor beta chain, ... | | Authors: | Archbold, J.K, Macdonald, W.A, Gras, S, Rossjohn, J. | | Deposit date: | 2008-07-23 | | Release date: | 2009-01-27 | | Last modified: | 2021-10-20 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.
J.Exp.Med., 206, 2009
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3FQR
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3FQU
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3FTG
 | | Crystal Structure of H2Db in complex with NP366-N3A variant peptide from influenza | | Descriptor: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | | Authors: | Gras, S, Guillonneau, C, Rossjohn, J. | | Deposit date: | 2009-01-12 | | Release date: | 2009-12-29 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Protective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold.
Plos Pathog., 6, 2010
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