1R6R
| Solution Structure of Dengue Virus Capsid Protein Reveals a New Fold | Descriptor: | Genome polyprotein | Authors: | Ma, L, Jones, C.T, Groesch, T.D, Kuhn, R.J, Post, C.B. | Deposit date: | 2003-10-16 | Release date: | 2004-02-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of dengue virus capsid protein reveals another fold Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
1R8S
| ARF1[DELTA1-17]-GDP IN COMPLEX WITH A SEC7 DOMAIN CARRYING THE MUTATION OF THE CATALYTIC GLUTAMATE TO LYSINE | Descriptor: | ADP-ribosylation factor 1, Arno, BETA-MERCAPTOETHANOL, ... | Authors: | Renault, L, Guibert, B, Cherfils, J. | Deposit date: | 2003-10-28 | Release date: | 2004-01-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor Nature, 426, 2003
|
|
1RPH
| |
1RE3
| Crystal Structure of Fragment D of BbetaD398A Fibrinogen with the Peptide Ligand Gly-His-Arg-Pro-Amide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ... | Authors: | Kostelansky, M.S, Betts, L, Gorkun, O.V, Lord, S.T. | Deposit date: | 2003-11-06 | Release date: | 2004-05-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | BbetaGlu397 and BbetaAsp398 but not BbetaAsp432 are required for "B:b" interactions. Biochemistry, 43, 2004
|
|
1R1W
| CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF THE HEPATOCYTE GROWTH FACTOR RECEPTOR C-MET | Descriptor: | HEPATOCYTE GROWTH FACTOR RECEPTOR | Authors: | Schiering, N, Knapp, S, Marconi, M, Flocco, M.M, Cui, J, Perego, R, Rusconi, L, Cristiani, C. | Deposit date: | 2003-09-25 | Release date: | 2003-10-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a Proc.Natl.Acad.Sci.USA, 100, 2003
|
|
1R55
| Crystal structure of the catalytic domain of human ADAM 33 | Descriptor: | (2S,3R)-N~4~-[(1S)-2,2-dimethyl-1-(methylcarbamoyl)propyl]-N~1~,2-dihydroxy-3-(2-methylpropyl)butanediamide, ADAM 33, CALCIUM ION, ... | Authors: | Orth, P, Reichert, P, Wang, W, Prosise, W.W, Yarosh-Tomaine, T, Hammond, G, Xiao, L, Mirza, U.A, Zou, J, Strickland, C, Taremi, S.S, Le, H.V, Madison, V. | Deposit date: | 2003-10-09 | Release date: | 2004-10-12 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Crystal structre of the catalytic domain of human ADAM33 J.Mol.Biol., 335, 2004
|
|
1R6Z
| The Crystal Structure of the Argonaute2 PAZ domain (as a MBP fusion) | Descriptor: | Chimera of Maltose-binding periplasmic protein and Argonaute 2, NICKEL (II) ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Song, J.J, Liu, J, Tolia, N.H, Schneiderman, J, Smith, S.K, Martienssen, R.A, Hannon, G.J, Joshua-Tor, L. | Deposit date: | 2003-10-17 | Release date: | 2004-01-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat.Struct.Biol., 10, 2003
|
|
1R58
| Crystal Structure of MetAP2 complexed with A357300 | Descriptor: | MANGANESE (II) ION, Methionine aminopeptidase 2, N'-((2S,3R)-3-AMINO-2-HYDROXY-5-(ISOPROPYLSULFANYL)PENTANOYL)-N-3-CHLOROBENZOYL HYDRAZIDE | Authors: | Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Ericken, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R. | Deposit date: | 2003-10-09 | Release date: | 2004-10-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | 3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2. Bioorg.Med.Chem.Lett., 14, 2004
|
|
1R6T
| crystal structure of human tryptophanyl-tRNA synthetase | Descriptor: | GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase | Authors: | Yang, X.-L, Otero, F.J, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P. | Deposit date: | 2003-10-16 | Release date: | 2004-01-06 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains Proc.Natl.Acad.Sci.USA, 100, 2003
|
|
1RDW
| Actin Crystal Dynamics: Structural Implications for F-actin Nucleation, Polymerization and Branching Mediated by the Anti-parallel Dimer | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Reutzel, R, Yoshioka, C, Govindasamy, L, Yarmola, E.G, Agbandje-Mckenna, M, Bubb, M.R, Mckenna, R. | Deposit date: | 2003-11-06 | Release date: | 2003-12-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Actin crystal dynamics: structural implications for F-actin nucleation, polymerization, and branching mediated by the anti-parallel dimer. J.Struct.Biol., 146, 2004
|
|
1RR2
| Propionibacterium shermanii transcarboxylase 5S subunit bound to 2-ketobutyric acid | Descriptor: | 2-KETOBUTYRIC ACID, COBALT (II) ION, transcarboxylase 5S subunit | Authors: | Hall, P.R, Zheng, R, Antony, L, Pusztai-Carey, M, Carey, P.R, Yee, V.C. | Deposit date: | 2003-12-08 | Release date: | 2004-09-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Transcarboxylase 5S structures: assembly and catalytic mechanism of a multienzyme complex subunit. Embo J., 23, 2004
|
|
1RRJ
| Structural Mechanisms of Camptothecin Resistance by Mutations in Human Topoisomerase I | Descriptor: | (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, 2-(1-DIMETHYLAMINOMETHYL-2-HYDROXY-8-HYDROXYMETHYL-9-OXO-9,11-DIHYDRO-INDOLIZINO[1,2-B]QUINOLIN-7-YL)-2-HYDROXY-BUTYRIC ACID, 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T*GP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', ... | Authors: | Chrencik, J.E, Staker, B.L, Burgin, A.B, Stewart, L, Redinbo, M.R. | Deposit date: | 2003-12-08 | Release date: | 2004-07-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Mechanisms of camptothecin resistance by human topoisomerase I mutations J.Mol.Biol., 339, 2004
|
|
1RGA
| |
1R05
| Solution Structure of Max B-HLH-LZ | Descriptor: | Max protein | Authors: | Sauv, S, Tremblay, L, Lavigne, P. | Deposit date: | 2003-09-19 | Release date: | 2003-10-21 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | The NMR solution structure of a mutant of the Max b/HLH/LZ free of DNA: insights into the specific and reversible DNA binding mechanism of dimeric transcription factors J.Mol.Biol., 342, 2004
|
|
1R0P
| Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met in complex with the microbial alkaloid K-252a | Descriptor: | Hepatocyte growth factor receptor, K-252A | Authors: | Schiering, N, Knapp, S, Marconi, M, Flocco, M.M, Cui, J, Perego, R, Rusconi, L, Cristiani, C. | Deposit date: | 2003-09-22 | Release date: | 2003-10-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a Proc.Natl.Acad.Sci.USA, 100, 2003
|
|
1QET
| TANDEM GU MISMATCHES IN RNA, NMR, 30 STRUCTURES | Descriptor: | RNA (5'-R(*GP*GP*AP*UP*GP*UP*CP*C)-3') | Authors: | Mcdowell, J.A, He, L, Chen, X, Turner, D.H. | Deposit date: | 1997-03-04 | Release date: | 1997-06-05 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Investigation of the structural basis for thermodynamic stabilities of tandem GU wobble pairs: NMR structures of (rGGAGUUCC)2 and (rGGAUGUCC)2. Biochemistry, 36, 1997
|
|
3Q1E
| Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase in complex with T4 | Descriptor: | 3,5,3',5'-TETRAIODO-L-THYRONINE, 5-hydroxyisourate hydrolase | Authors: | Cendron, L, Ramazzina, I, Percudani, R, Zanotti, G, Berni, R. | Deposit date: | 2010-12-17 | Release date: | 2011-05-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign. J.Mol.Biol., 409, 2011
|
|
1QMS
| Head-to-Tail Dimer of Calicheamicin gamma-1-I Oligosaccharide Bound to DNA Duplex, NMR, 9 Structures | Descriptor: | CALICHEAMICIN GAMMA-1-OLIGOSACCHARIDE, DNA (5'-D(*GP*CP*AP*CP*CP*TP*TP*CP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*GP*GP*AP*AP*GP*GP*TP*GP*C)-3'), ... | Authors: | Bifulco, G, Galeone, A, Nicolaou, K.C, Chazin, W.J, Gomez-Paloma, L. | Deposit date: | 1999-10-06 | Release date: | 1999-10-12 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Complex between the Head-to-Tail Dimer of Calicheamicin Gamma-1-I Oligosaccharide and a DNA Duplex Containing D(ACCT) and D(TCCT) High-Affinity Binding Sites J.Am.Chem.Soc., 120, 1998
|
|
1R3B
| Solution structure of xenopus laevis Mob1 | Descriptor: | MOB1 | Authors: | Ponchon, L, Dumas, C, Kajava, A.V, Fesquet, D, Padilla, A. | Deposit date: | 2003-10-01 | Release date: | 2004-09-28 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR solution structure of Mob1, a mitotic exit network protein and its interaction with an NDR kinase peptide J.Mol.Biol., 337, 2004
|
|
1R5H
| Crystal Structure of MetAP2 complexed with A320282 | Descriptor: | MANGANESE (II) ION, Methionine aminopeptidase 2, N'-(2S,3R)-3-AMINO-4-CYCLOHEXYL-2-HYDROXY-BUTANO-N-(4-METHYLPHENYL)HYDRAZIDE | Authors: | Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Erickson, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R. | Deposit date: | 2003-10-10 | Release date: | 2004-10-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | 3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2. Bioorg.Med.Chem.Lett., 14, 2004
|
|
1S9L
| NMR Solution Structure of a Parallel LNA Quadruplex | Descriptor: | 5'-((TLN)P*(LCG)P*(LCG)P*(LCG)P*(TLN))-3' | Authors: | Randazzo, A, Esposito, V, Ohlenschlager, O, Ramachandran, R, Mayola, L. | Deposit date: | 2004-02-05 | Release date: | 2004-06-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR solution structure of a parallel LNA quadruplex. Nucleic Acids Res., 32, 2004
|
|
1S2X
| Crystal structure of Cag-Z from Helicobacter pylori | Descriptor: | Cag-Z, ISOPROPYL ALCOHOL | Authors: | Cendron, L, Seydel, A, Angelini, A, Battistutta, R, Zanotti, G. | Deposit date: | 2004-01-12 | Release date: | 2004-07-27 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of CagZ, a protein from the Helicobacter pylori pathogenicity island that encodes for a type IV secretion system J.Mol.Biol., 340, 2004
|
|
1S5O
| Structural and Mutational Characterization of L-carnitine Binding to Human carnitine Acetyltransferase | Descriptor: | CARNITINE, carnitine acetyltransferase isoform 2 | Authors: | Govindasamy, L, Kukar, T, Lian, W, Pedersen, B, Gu, Y, Agbandje-Mckenna, M, Jin, S, Mckenna, R, Wu, D. | Deposit date: | 2004-01-21 | Release date: | 2004-02-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and mutational characterization of l-carnitine binding to human carnitine acetyltransferase. J.Struct.Biol., 146, 2004
|
|
1S97
| DPO4 with GT mismatch | Descriptor: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*G)-3', 5'-D(*T*TP*CP*AP*GP*TP*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', ... | Authors: | Trincao, J, Johnson, R.E, Wolfle, W.T, Escalante, C.R, Prakash, S, Prakash, L, Aggarwal, A.K. | Deposit date: | 2004-02-03 | Release date: | 2004-04-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Dpo4 is hindered in extending a G.T mismatch by a reverse wobble Nat.Struct.Mol.Biol., 11, 2004
|
|
1SB6
| Solution structure of a cyanobacterial copper metallochaperone, ScAtx1 | Descriptor: | copper chaperone ScAtx1 | Authors: | Banci, L, Bertini, I, Ciofi-Baffoni, S, Su, X.C, Borrelly, G.P, Robinson, N.J, Structural Proteomics in Europe (SPINE) | Deposit date: | 2004-02-10 | Release date: | 2004-04-27 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution Structures of a Cyanobacterial Metallochaperone: INSIGHT INTO AN ATYPICAL COPPER-BINDING MOTIF. J.Biol.Chem., 279, 2004
|
|