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8HLP
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BU of 8hlp by Molmil
Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 (apo)
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Wei, Y, Yu, Z, Zhao, Y.
Deposit date:2022-11-30
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors.
Nat Commun, 15, 2024
8HMA
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BU of 8hma by Molmil
Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 in complex with tetrandrine (TET)
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6,6',7,12-tetramethoxy-2,2'-dimethyl-1beta-3,4-didehydroberbaman, ...
Authors:Wei, Y, Yu, Z, Zhao, Y.
Deposit date:2022-12-02
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors.
Nat Commun, 15, 2024
1HSJ
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BU of 1hsj by Molmil
SARR MBP FUSION STRUCTURE
Descriptor: FUSION PROTEIN CONSISTING OF STAPHYLOCOCCUS ACCESSORY REGULATOR PROTEIN R AND MALTOSE BINDING PROTEIN, alpha-D-glucopyranose
Authors:Zhang, G.
Deposit date:2000-12-26
Release date:2001-06-06
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the SarR protein from Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 98, 2001
8WFJ
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BU of 8wfj by Molmil
human glycine transporter 1 in complex with ALX-5407 in inward facing conformation
Descriptor: ALX5407, Sodium- and chloride-dependent glycine transporter 1
Authors:Wei, Y, Zhao, Y.
Deposit date:2023-09-19
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
8WFL
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BU of 8wfl by Molmil
human glycine transporter 1 in complex with PF-03463275 in outward facing conformation
Descriptor: PF-3463275, Sodium- and chloride-dependent glycine transporter 1
Authors:Wei, Y, Zhao, Y.
Deposit date:2023-09-19
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
8WFI
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BU of 8wfi by Molmil
human glycine transporter 1 in complex with glycine in occluded conformation
Descriptor: CHLORIDE ION, GLYCINE, Isoform GlyT-1B of Sodium- and chloride-dependent glycine transporter 1, ...
Authors:Wei, Y, Zhao, Y.
Deposit date:2023-09-19
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
8W8D
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BU of 8w8d by Molmil
Structural mechanism of inhibition of the Rho transcription termination factor by Rof
Descriptor: Protein rof, Transcription termination factor Rho
Authors:Zhang, J, Wang, C.
Deposit date:2023-09-01
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:A widely conserved protein Rof inhibits transcription termination factor Rho and promotes Salmonella virulence program.
Nat Commun, 15, 2024
8WFK
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BU of 8wfk by Molmil
human glycine transporter 1 in complex with SSR504734 in outward facing conformation
Descriptor: CHLORIDE ION, SODIUM ION, SSR504734, ...
Authors:Wei, Y, Zhao, Y.
Deposit date:2023-09-19
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
4RL5
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BU of 4rl5 by Molmil
Crystal structure of the Arabidopsis exocyst subunit exo70 family protein A1
Descriptor: Exocyst complex component EXO70A1
Authors:Zhang, Z.-M, Zhang, C, Song, J.
Deposit date:2014-10-15
Release date:2015-11-25
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Endosidin2 targets conserved exocyst complex subunit EXO70 to inhibit exocytosis.
Proc.Natl.Acad.Sci.USA, 113, 2016
2R1H
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BU of 2r1h by Molmil
met-Trout IV hemoglobin at pH 6.3
Descriptor: 1,2-ETHANEDIOL, Hemoglobin subunit alpha-4, Hemoglobin subunit beta-4, ...
Authors:Aranda IV, R, Worley, C.E, Richards, M.P, Phillips Jr, G.N.
Deposit date:2007-08-22
Release date:2008-09-02
Last modified:2013-01-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss.
Proteins, 75, 2008
2QSS
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BU of 2qss by Molmil
Bovine hemoglobin at pH 6.3
Descriptor: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
Authors:Aranda IV, R, Richards, M.P, Phillips Jr, G.N.
Deposit date:2007-07-31
Release date:2008-09-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss.
Proteins, 75, 2008
2QSP
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BU of 2qsp by Molmil
Bovine Hemoglobin at pH 5.7
Descriptor: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE
Authors:Aranda IV, R, Richards, M.P, Phillips Jr, G.N.
Deposit date:2007-07-31
Release date:2008-09-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss.
Proteins, 75, 2008
1H69
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BU of 1h69 by Molmil
CRYSTAL STRUCTURE OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE CO WITH 2,3,5,6,TETRAMETHYL-P-BENZOQUINONE (DUROQUINONE) AT 2.5 ANGSTROM RESOLUTION
Descriptor: 3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1
Authors:Faig, M, Bianchet, M.A, Chen, S, Winski, S, Ross, D, Amzel, L.M.
Deposit date:2001-06-08
Release date:2001-09-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structure-Based Development of Anticancer Drugs: Complexes of Nad(P)H:Quinone Oxidoreductase 1 with Chemotherapeutic Quinones
Structure, 9, 2001
1H66
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BU of 1h66 by Molmil
CRYSTAL STRUCTURE OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE CO WITH 2,5-diaziridinyl-3-hydroxyl-6-methyl-1,4-benzoquinone
Descriptor: 2,5-DIAZIRIDIN-1-YL-3-(HYDROXYMETHYL)-6-METHYLCYCLOHEXA-2,5-DIENE-1,4-DIONE, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1
Authors:Faig, M, Bianchet, M.A, Winski, S, Ross, D, Amzel, L.M.
Deposit date:2001-06-06
Release date:2001-09-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Based Development of Anticancer Drugs: Complexes of Nad(P)H:Quinone Oxidoreductase 1 with Chemotherapeutic Quinones
Structure, 9, 2001
4MZD
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BU of 4mzd by Molmil
High resolution crystal structure of the nisin leader peptidase NisP from Lactococcus lactis
Descriptor: Nisin leader peptide-processing serine protease NisP
Authors:Rao, Z.H, Xu, Y.Y, Li, X, Yang, W.
Deposit date:2013-09-30
Release date:2014-06-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structure of the nisin leader peptidase NisP revealing a C-terminal autocleavage activity.
Acta Crystallogr.,Sect.D, 70, 2014
2ICK
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BU of 2ick by Molmil
Human isopentenyl diphophate isomerase complexed with substrate analog
Descriptor: DIMETHYLALLYL DIPHOSPHATE, Isopentenyl-diphosphate delta isomerase, MANGANESE (II) ION
Authors:Zheng, W, Bartlam, M, Rao, Z.
Deposit date:2006-09-12
Release date:2007-03-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:The crystal structure of human isopentenyl diphosphate isomerase at 1.7 A resolution reveals its catalytic mechanism in isoprenoid biosynthesis
J.Mol.Biol., 366, 2007
7XCZ
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BU of 7xcz by Molmil
Cryo-EM structure of SARS-CoV-2 Delta RBD in complex with BA7054 and BA7125 fab (local refinement)
Descriptor: BA7054 fab, BA7125 fab, Spike glycoprotein
Authors:Liu, Z, Liu, S.
Deposit date:2022-03-26
Release date:2023-03-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5.
Cell Discov, 9, 2023
7XDK
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BU of 7xdk by Molmil
Cryo-EM structure of SARS-CoV-2 Delta Spike protein in complex with BA7054 and BA7125 fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BA7054 fab, ...
Authors:Liu, Z, Lui, S, Gao, Y.
Deposit date:2022-03-27
Release date:2023-03-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5.
Cell Discov, 9, 2023
7XDA
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BU of 7xda by Molmil
Cryo-EM structure of SARS-CoV-2 Delta RBD in complex with BA7208 and BA7125 fab (local refinement)
Descriptor: BA7125 fab, BA7208 fab, Spike glycoprotein
Authors:Liu, Z, Liu, S, Liu, S.
Deposit date:2022-03-26
Release date:2023-03-01
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5.
Cell Discov, 9, 2023
7XDB
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BU of 7xdb by Molmil
Cryo-EM structure of SARS-CoV-2 Omicron Spike protein in complex with BA7208 fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BA7208 fab, ...
Authors:Liu, Z, Liu, S, Gao, Y.Z.
Deposit date:2022-03-26
Release date:2023-03-01
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5.
Cell Discov, 9, 2023
7XDL
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BU of 7xdl by Molmil
Cryo-EM structure of SARS-CoV-2 Delta Spike protein in complex with BA7208 and BA7125 fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BA7125 fab, ...
Authors:Liu, Z, Liu, S, Yuanzhu, G.
Deposit date:2022-03-27
Release date:2023-03-15
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5.
Cell Discov, 9, 2023
2ICJ
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BU of 2icj by Molmil
The crystal structure of human isopentenyl diphophate isomerase
Descriptor: Isopentenyl-diphosphate delta isomerase, MAGNESIUM ION, SULFATE ION
Authors:Zheng, W, Bartlam, M, Rao, Z.
Deposit date:2006-09-12
Release date:2007-03-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure of human isopentenyl diphosphate isomerase at 1.7 A resolution reveals its catalytic mechanism in isoprenoid biosynthesis
J.Mol.Biol., 366, 2007
8HDJ
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BU of 8hdj by Molmil
Periplasmic domain of RsgI2 of Clostridium thermocellum
Descriptor: Anti-sigma-I factor RsgI2, Periplasmic domain of RsgI2
Authors:Chen, C, Dong, S, Feng, Y.G.
Deposit date:2022-11-04
Release date:2023-05-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Essential autoproteolysis of bacterial anti-sigma factor RsgI for transmembrane signal transduction.
Sci Adv, 9, 2023
8HER
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BU of 8her by Molmil
Solution structure of the periplasmic domain of RsgI6 from Clostridium thermocellum
Descriptor: Anti-sigma factor
Authors:Chen, C, Feng, Y.
Deposit date:2022-11-08
Release date:2023-05-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Essential autoproteolysis of bacterial anti-sigma factor RsgI for transmembrane signal transduction.
Sci Adv, 9, 2023
8HEP
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BU of 8hep by Molmil
Solution structure of the periplasmic domain of the anti-sigma factor RsgI1 from Clostridium thermocellum
Descriptor: Anti-sigma factor
Authors:Chen, C, Feng, Y.
Deposit date:2022-11-08
Release date:2023-05-24
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Essential autoproteolysis of bacterial anti-sigma factor RsgI for transmembrane signal transduction.
Sci Adv, 9, 2023

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