8HIT
| Crystal structure of anti-CTLA-4 humanized IgG1 MAb--JS007 in complex with human CTLA-4 | Descriptor: | Cytotoxic T-lymphocyte protein 4, JS007-VH, JS007-VL | Authors: | Tan, S, Shi, Y, Wang, Q, Gao, G.F, Guan, J, Chai, Y, Qi, J. | Deposit date: | 2022-11-21 | Release date: | 2023-02-01 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Characterization of the high-affinity anti-CTLA-4 monoclonal antibody JS007 for immune checkpoint therapy of cancer. Mabs, 15, 2023
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8KG8
| Yeast replisome in state II | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ... | Authors: | Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. | Deposit date: | 2023-08-17 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (4.23 Å) | Cite: | Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
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8KG9
| Yeast replisome in state III | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ... | Authors: | Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. | Deposit date: | 2023-08-17 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (4.52 Å) | Cite: | Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
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8KG6
| Yeast replisome in state I | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ... | Authors: | Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. | Deposit date: | 2023-08-17 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
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8KA8
| Cryo-EM structure of SARS-CoV-2 Delta RBD in complex with golden hamster ACE2 (local refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | Authors: | Niu, S, Zhao, Z.N, Chai, Y, Gao, G.F. | Deposit date: | 2023-08-02 | Release date: | 2024-01-31 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Structural basis and analysis of hamster ACE2 binding to different SARS-CoV-2 spike RBDs. J.Virol., 98, 2024
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8KC2
| Cryo-EM structure of SARS-CoV-2 BA.3 RBD in complex with golden hamster ACE2 (local refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | Authors: | Niu, S, Zhao, Z.N, Chai, Y, Gao, G.F. | Deposit date: | 2023-08-05 | Release date: | 2024-01-31 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis and analysis of hamster ACE2 binding to different SARS-CoV-2 spike RBDs. J.Virol., 98, 2024
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8ZMO
| Structure of a triple-helix region of human Collagen type XVII from Trautec | Descriptor: | collagen type XVII | Authors: | Chu, Y, Zhai, Y, Fan, X, Fu, S, Li, J, Wu, X, Cai, H, Wang, X, Li, D, Feng, P, Cao, K, Qian, S. | Deposit date: | 2024-05-23 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of a triple-helix region of human Collagen type XVII from Trautec To Be Published
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8ZMW
| Structure of a triple-helix region of human Collagen type VII from Trautec | Descriptor: | ACETATE ION, collagen type VII | Authors: | Chu, Y, Zhai, Y, Fan, X, Fu, S, Li, J, Wu, X, Cai, H, Wang, X, Li, D, Feng, P, Cao, K, Qian, S. | Deposit date: | 2024-05-24 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of a triple-helix region of human Collagen type VII from Trautec To Be Published
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8ZMM
| Structure of a triple-helix region of human Collagen type IV from Trautec | Descriptor: | collagen type IV | Authors: | Chu, Y, Zhai, Y, Fan, X, Fu, S, Li, J, Wu, X, Cai, H, Wang, X, Li, D, Feng, P, Cao, K, Qian, S. | Deposit date: | 2024-05-23 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure of a triple-helix region of human Collagen type IV from Trautec To Be Published
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8GVB
| The complex between public TCR TD08 and HLA-A24 bound to HIV-1 Nef138-8 peptide | Descriptor: | 8-mer peptide from Protein Nef, Beta-2-microglobulin, MHC class I antigen, ... | Authors: | Gao, G.F, Shi, Y, Ma, K, Chai, Y, Guan, J, Qi, J, Tan, S, Dong, T, Iwamoto, A, Kawana-Tachikawa, A. | Deposit date: | 2022-09-14 | Release date: | 2022-10-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors. J Immunol., 209, 2022
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8GVG
| The complex between public TCR TD08 and HLA-A24 bound to HIV-1 Nef138-8 (2F) peptide | Descriptor: | Beta-2-microglobulin, MHC class I antigen, TD08 TCR alpha chain, ... | Authors: | Gao, G.F, Shi, Y, Ma, K, Chai, Y, Guan, J, Qi, J, Tan, S, Dong, T, Iwamoto, A, Kawana-Tachikawa, A. | Deposit date: | 2022-09-15 | Release date: | 2022-10-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.37 Å) | Cite: | Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors. J Immunol., 209, 2022
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8GVI
| The complex between H25-11 TCR and HLA-A24 bound to HIV-1 Nef138-8 peptide | Descriptor: | 8-mer peptide from Protein Nef, Beta-2-microglobulin, H25-11 TCR alpha chain, ... | Authors: | Gao, G.F, Shi, Y, Tan, S, Ma, K, Chai, Y, Qi, J, Kawana-Tachikawa, A, Iwamoto, A, Dong, T, Guan, J. | Deposit date: | 2022-09-15 | Release date: | 2022-10-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors. J Immunol., 209, 2022
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8GPX
| YFV_E_YD73Fab_postfusion | Descriptor: | Envelope protein, YD73Fab_H, YD73Fab_K | Authors: | Li, Y, Wu, L, Chai, Y, Qi, J, Yan, J, Gao, G.F. | Deposit date: | 2022-08-27 | Release date: | 2022-11-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus. Innovation (N Y), 3, 2022
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8I5D
| Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) | Descriptor: | Beta-2-microglobulin, MHC class I antigen (Fragment), TCR alpha chain, ... | Authors: | Lu, D, Chen, Y, Jiang, M, Tan, S.G, Chai, Y, Gao, G.F. | Deposit date: | 2023-01-25 | Release date: | 2023-08-23 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK) Nat Commun, 2023
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8W7S
| Yeast replisome in state IV | Descriptor: | Cell division control protein 45, DNA (71-mer), DNA polymerase alpha-binding protein, ... | Authors: | Dang, S, Zhai, Y, Feng, J, Yu, D. | Deposit date: | 2023-08-31 | Release date: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (7.39 Å) | Cite: | Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
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8W7M
| Yeast replisome in state V | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (71-mer), ... | Authors: | Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. | Deposit date: | 2023-08-30 | Release date: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (4.12 Å) | Cite: | Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
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5V4S
| CryoEM Structure of a Prokaryotic Cyclic Nucleotide-Gated Ion Channel | Descriptor: | Transporter, cation channel family / cyclic nucleotide-binding domain multi-domain protein | Authors: | James, Z.M, Borst, A.J, Haitin, Y, Frenz, B, DiMaio, F, Zagotta, W.N, Veesler, D. | Deposit date: | 2017-03-10 | Release date: | 2017-04-12 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | CryoEM structure of a prokaryotic cyclic nucleotide-gated ion channel. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8Q4I
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8Q4J
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3KO1
| Cystal structure of thermosome from Acidianus tengchongensis strain S5 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Chaperonin | Authors: | Huo, Y, Zhang, K, Hu, Z, Wang, L, Zhai, Y, Zhou, Q, Lander, G, He, Y, Zhu, J, Xu, W, Dong, Z, Sun, F. | Deposit date: | 2009-11-12 | Release date: | 2010-11-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Crystal structure of group II chaperonin in the open state. Structure, 18, 2010
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6J29
| The structure of HLA-A*3003/MTB | Descriptor: | Beta-2-microglobulin, HLA-A*3003, MTB | Authors: | Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, F.G, Lou, Y.L, Liu, W.J. | Deposit date: | 2018-12-31 | Release date: | 2019-09-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides. Front Immunol, 10, 2019
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5WXC
| Crystal Structure of HLA-A*2402 in complex with avian influenza A(H7N9) virus-derived peptide H7-25 (data set 2) | Descriptor: | Beta-2-microglobulin, H7-25-F, HLA class I histocompatibility antigen, ... | Authors: | Zhao, M, Liu, K, Chai, Y, Qi, J, Liu, J, Gao, G.F. | Deposit date: | 2017-01-07 | Release date: | 2018-01-17 | Last modified: | 2019-07-31 | Method: | X-RAY DIFFRACTION (2.295 Å) | Cite: | Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses. Mbio, 9, 2018
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6J1V
| The structure of HLA-A*3003/RT313 | Descriptor: | Beta-2-microglobulin, HLA-A*3003, RT313 | Authors: | Zhu, S.Y, Liu, K.F, Chai, Y, Ding, C.M, Lv, J.X, Gao, G.F, Lou, Y.L, Liu, W.J. | Deposit date: | 2018-12-29 | Release date: | 2019-09-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides. Front Immunol, 10, 2019
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5WWU
| Crystal Structure of HLA-A*2402 in complex with 2009 pandemic influenza A(H1N1) virus and avian influenza A(H5N1) virus-derived peptide H1-25 | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... | Authors: | Zhao, M, Liu, K, Chai, Y, Qi, J, Liu, J, Gao, G.F. | Deposit date: | 2017-01-05 | Release date: | 2018-01-17 | Last modified: | 2019-07-31 | Method: | X-RAY DIFFRACTION (2.794 Å) | Cite: | Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses. Mbio, 9, 2018
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6K7O
| Complex structure of LILRB4 and h128-3 antibody | Descriptor: | Leukocyte immunoglobulin-like receptor subfamily B member 4, h128-3 Fab heavy chain, h128-3 Fab light chain | Authors: | Song, H, Chai, Y, Xu, X, Gao, F.G. | Deposit date: | 2019-06-08 | Release date: | 2019-07-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.004 Å) | Cite: | Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development. Cancer Immunol Res, 7, 2019
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