5IZH
| |
5J1P
| |
5MV0
| Structure of an N-terminal domain of a reptarenavirus L protein | Descriptor: | L protein, PHOSPHATE ION | Authors: | Rosenthal, M, Gogrefe, N, Reguera, J, Vogel, D, Rauschenberger, B, Cusack, S, Gunther, S, Reindl, S. | Deposit date: | 2017-01-14 | Release date: | 2017-05-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structural insights into reptarenavirus cap-snatching machinery. PLoS Pathog., 13, 2017
|
|
5MUZ
| Structure of a C-terminal domain of a reptarenavirus L protein | Descriptor: | L protein | Authors: | Rosenthal, M, Gogrefe, N, Reguera, J, Vogel, D, Rauschenberger, B, Cusack, S, Gunther, S, Reindl, S. | Deposit date: | 2017-01-14 | Release date: | 2017-05-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.776 Å) | Cite: | Structural insights into reptarenavirus cap-snatching machinery. PLoS Pathog., 13, 2017
|
|
5MUY
| Structure of a C-terminal domain of a reptarenavirus L protein with m7GTP | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, L protein | Authors: | Rosenthal, M, Gogrefe, N, Reguera, J, Vogel, D, Rauschenberger, B, Cusack, S, Gunther, S, Reindl, S. | Deposit date: | 2017-01-14 | Release date: | 2017-05-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural insights into reptarenavirus cap-snatching machinery. PLoS Pathog., 13, 2017
|
|
5J1N
| |
5MUS
| Structure of the C-terminal domain of a reptarenavirus L protein | Descriptor: | CHLORIDE ION, GLYCEROL, L protein | Authors: | Rosenthal, M, Gogrefe, N, Reguera, J, Vogel, D, Rauschenberger, B, Cusack, S, Gunther, S, Reindl, S. | Deposit date: | 2017-01-14 | Release date: | 2017-05-17 | Last modified: | 2017-05-24 | Method: | X-RAY DIFFRACTION (2.009 Å) | Cite: | Structural insights into reptarenavirus cap-snatching machinery. PLoS Pathog., 13, 2017
|
|
5AGH
| Crystal structure of the LeuRS editing domain of Candida albicans Mutant K510A | Descriptor: | ACETATE ION, POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE | Authors: | Zhao, H, Palencia, A, Seiradake, E, Ghaemi, Z, Luthey-Schulten, Z, Cusack, S, Martinis, S.A. | Deposit date: | 2015-02-02 | Release date: | 2015-07-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight Into the Leucyl-tRNA Synthetase Editing Mechanism. Acs Chem.Biol., 10, 2015
|
|
5AGR
| Crystal structure of the LeuRS editing domain of Mycobacterium tuberculosis in complex with the adduct (S)-3-(Aminomethyl)-7-ethoxybenzo[c][1,2]oxaborol-1(3H)-ol-AMP | Descriptor: | 1,2-ETHANEDIOL, 3-AMINOMETHYL-7-(ETHOXY)-3H-BENZO[C][1,2]OXABOROL-1-OL modified adenosine, LEUCINE, ... | Authors: | Palencia, A, Li, X, Alley, M.R.K, Ding, C, Easom, E.E, Hernandez, V, Meewan, M, Mohan, M, Rock, F.L, Franzblau, S.G, Wang, Y, Lenaerts, A.J, Parish, T, Cooper, C.B, Waters, M.G, Ma, Z, Mendoza, A, Barros, D, Cusack, S, Plattner, J.J. | Deposit date: | 2015-02-03 | Release date: | 2016-03-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium Tuberculosis that Target Leucyl-tRNA Synthetase. Antimicrob.Agents Chemother., 60, 2016
|
|
5AGJ
| Crystal structure of the LeuRS editing domain of Candida albicans in complex with the adduct AN2690-AMP | Descriptor: | POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE, [(6-AMINO-9H-PURIN-9-YL)-[5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROLE]-4'YL]METHYL DIHYDROGEN PHOSPHATE | Authors: | Zhao, H, Palencia, A, Seiradake, E, Ghaemi, Z, Luthey-Schulten, Z, Cusack, S, Martinis, S.A. | Deposit date: | 2015-02-02 | Release date: | 2015-07-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight Into the Leucyl-tRNA Synthetase Editing Mechanism. Acs Chem.Biol., 10, 2015
|
|
5AGI
| Crystal structure of the LeuRS editing domain of Candida albicans Mutant K510A in complex with the adduct formed by AN2690-AMP | Descriptor: | GLYCEROL, POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE, [(6-AMINO-9H-PURIN-9-YL)-[5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROLE]-4'YL]METHYL DIHYDROGEN PHOSPHATE | Authors: | Zhao, H, Palencia, A, Seiradake, E, Ghaemi, Z, Luthey-Schulten, Z, Cusack, S, Martinis, S.A. | Deposit date: | 2015-02-02 | Release date: | 2015-07-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight Into the Leucyl-tRNA Synthetase Editing Mechanism. Acs Chem.Biol., 10, 2015
|
|
1QHV
| HUMAN ADENOVIRUS SEROTYPE 2 FIBRE HEAD | Descriptor: | PROTEIN (ADENOVIRUS FIBRE), SULFATE ION | Authors: | Van Raaij, M.J, Louis, N, Chroboczek, J, Cusack, S. | Deposit date: | 1999-05-28 | Release date: | 1999-09-29 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Structure of the human adenovirus serotype 2 fiber head domain at 1.5 A resolution. Virology, 262, 1999
|
|
1QIU
| |
1X9T
| The crystal structure of human adenovirus 2 penton base in complex with an ad2 N-terminal fibre peptide | Descriptor: | N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE, N-terminal peptide of Fiber protein, Penton protein | Authors: | Zubieta, C, Schoehn, G, Chroboczek, J, Cusack, S. | Deposit date: | 2004-08-24 | Release date: | 2005-01-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | The structure of the human adenovirus 2 penton Mol.Cell, 17, 2005
|
|
1X9P
| The crystal structure of human adenovirus 2 penton base | Descriptor: | N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE, Penton protein, SULFATE ION | Authors: | Zubieta, C, Schoehn, G, Chroboczek, J, Cusack, S. | Deposit date: | 2004-08-24 | Release date: | 2005-01-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The structure of the human adenovirus 2 penton Mol.Cell, 17, 2005
|
|
1ZZJ
| Structure of the third KH domain of hnRNP K in complex with 15-mer ssDNA | Descriptor: | 5'-D(*TP*TP*CP*CP*CP*CP*TP*CP*CP*CP*CP*AP*TP*TP*T)-3', Heterogeneous nuclear ribonucleoprotein K | Authors: | Backe, P.H, Messias, A.C, Ravelli, R.B, Sattler, M, Cusack, S. | Deposit date: | 2005-06-14 | Release date: | 2005-08-09 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | X-Ray Crystallographic and NMR Studies of the Third KH Domain of hnRNP K in Complex with Single-Stranded Nucleic Acids STRUCTURE, 13, 2005
|
|
1D4R
| 29-mer fragment of human srp rna helix 6 | Descriptor: | 29-MER OF MODIFIED SRP RNA HELIX 6, MAGNESIUM ION | Authors: | Wild, K, Weichenrieder, O, Leonard, G.A, Cusack, S. | Deposit date: | 1999-10-05 | Release date: | 1999-12-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The 2 A structure of helix 6 of the human signal recognition particle RNA Structure Fold.Des., 7, 1999
|
|
1ZZK
| Crystal Structure of the third KH domain of hnRNP K at 0.95A resolution | Descriptor: | Heterogeneous nuclear ribonucleoprotein K | Authors: | Backe, P.H, Messias, A.C, Ravelli, R.B, Sattler, M, Cusack, S. | Deposit date: | 2005-06-14 | Release date: | 2005-08-09 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | X-Ray Crystallographic and NMR Studies of the Third KH Domain of hnRNP K in Complex with Single-Stranded Nucleic Acids STRUCTURE, 13, 2005
|
|
1ZZI
| Crystal Structure Analysis of the third KH domain of hnRNP K in complex with ssDNA | Descriptor: | 5'-D(*CP*TP*CP*CP*CP*C)-3', Heterogeneous nuclear ribonucleoprotein K | Authors: | Backe, P.H, Messias, A.C, Ravelli, R.B, Sattler, M, Cusack, S. | Deposit date: | 2005-06-14 | Release date: | 2005-08-09 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-Ray Crystallographic and NMR Studies of the Third KH Domain of hnRNP K in Complex with Single-Stranded Nucleic Acids STRUCTURE, 13, 2005
|
|
1E8O
| Core of the Alu domain of the mammalian SRP | Descriptor: | 7SL RNA, SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN, SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN, ... | Authors: | Weichenrieder, O, Wild, K, Strub, K, Cusack, S. | Deposit date: | 2000-09-28 | Release date: | 2000-11-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure and Assembly of the Alu Domain of the Mammalian Signal Recognition Particle Nature, 408, 2000
|
|
2B1W
| |
5M3H
| Bat influenza A/H17N10 polymerase bound to four heptad repeats of serine 5 phosphorylated Pol II CTD | Descriptor: | PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Lukarska, M, Pflug, A, Cusack, S. | Deposit date: | 2016-10-14 | Release date: | 2016-12-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of an essential interaction between influenza polymerase and Pol II CTD. Nature, 541, 2017
|
|
8AZA
| Structure of RIP2K dimer bound to the XIAP BIR2 domain | Descriptor: | E3 ubiquitin-protein ligase XIAP, Receptor-interacting serine/threonine-protein kinase 2, ZINC ION | Authors: | Pellegrini, E, Cusack, S. | Deposit date: | 2022-09-05 | Release date: | 2022-10-26 | Last modified: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface. Life Sci Alliance, 6, 2023
|
|
7OE7
| Apo-structure of Lassa virus L protein (well-resolved alpha ribbon) [APO-RIBBON] | Descriptor: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | Authors: | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | Deposit date: | 2021-05-01 | Release date: | 2021-12-01 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.73 Å) | Cite: | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
|
|
7OJK
| Lassa virus L protein bound to the distal promoter duplex [DISTAL-PROMOTER] | Descriptor: | 3' RNA, 5' RNA, RNA-directed RNA polymerase L, ... | Authors: | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | Deposit date: | 2021-05-16 | Release date: | 2021-12-01 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.89 Å) | Cite: | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
|
|