1GLO
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![BU of 1glo by Molmil](/molmil-images/mine/1glo) | Crystal Structure of Cys25Ser mutant of human cathepsin S | Descriptor: | CATHEPSIN S | Authors: | Turkenburg, J.P, Lamers, M.B.A.C, Brzozowski, A.M, Wright, L.M, Hubbard, R.E, Sturt, S.L, Williams, D.H. | Deposit date: | 2001-08-31 | Release date: | 2002-08-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of a Cys25->Ser Mutant of Human Cathepsin Cathepsin S Acta Crystallogr.,Sect.D, 58, 2002
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2MVD
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![BU of 2mvd by Molmil](/molmil-images/mine/2mvd) | Solution structure of [GlnB22]-insulin mutant at pH 1.9 | Descriptor: | Insulin A chain, Insulin B chain | Authors: | Hexnerova, R, Krizkova, K, Maletinska, L, Jiracek, J, Brzozowski, A.M, Zakova, L, Veverka, V. | Deposit date: | 2014-10-02 | Release date: | 2014-12-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural and Functional Study of the GlnB22-Insulin Mutant Responsible for Maturity-Onset Diabetes of the Young. Plos One, 9, 2014
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1OJJ
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![BU of 1ojj by Molmil](/molmil-images/mine/1ojj) | Anatomy of glycosynthesis: Structure and kinetics of the Humicola insolens Cel7BE197A and E197S glycosynthase mutants | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOGLUCANASE I, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, ... | Authors: | Ducros, V.M.-A, Tarling, C.A, Zechel, D.L, Brzozowski, A.M, Frandsen, T.P, Von Ossowski, I, Schulein, M, Withers, S.G, Davies, G.J. | Deposit date: | 2003-07-10 | Release date: | 2004-01-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Anatomy of Glycosynthesis: Structure and Kinetics of the Humicola Insolens Cel7B E197A and E197S Glycosynthase Mutants Chem.Biol., 10, 2003
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1OJK
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![BU of 1ojk by Molmil](/molmil-images/mine/1ojk) | Anatomy of glycosynthesis: Structure and kinetics of the Humicola insolens Cel7BE197A and E197S glycosynthase mutants | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOGLUCANASE I, GLYCEROL, ... | Authors: | Ducros, V.M.-A, Tarling, C.A, Zechel, D.L, Brzozowski, A.M, Frandsen, T.P, Von Ossowski, I, Schulein, M, Withers, S.G, Davies, G.J. | Deposit date: | 2003-07-10 | Release date: | 2004-01-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Anatomy of Glycosynthesis: Structure and Kinetics of the Humicola Insolens Cel7B E197A and E197S Glycosynthase Mutants Chem.Biol., 10, 2003
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1OJI
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![BU of 1oji by Molmil](/molmil-images/mine/1oji) | Anatomy of glycosynthesis: Structure and kinetics of the Humicola insolens Cel7B E197A and E197S glycosynthase mutants | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOGLUCANASE I, GLYCEROL | Authors: | Ducros, V.M.-A, Tarling, C.A, Zechel, D.L, Brzozowski, A.M, Frandsen, T.P, Von Ossowski, I, Schulein, M, Withers, S.G, Davies, G.J. | Deposit date: | 2003-07-10 | Release date: | 2004-01-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Anatomy of Glycosynthesis: Structure and Kinetics of the Humicola Insolens Cel7B E197A and E197S Glycosynthase Mutants Chem.Biol., 10, 2003
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2FYI
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![BU of 2fyi by Molmil](/molmil-images/mine/2fyi) | Crystal Structure of the Cofactor-Binding Domain of the Cbl Transcriptional Regulator | Descriptor: | HTH-type transcriptional regulator cbl | Authors: | Stec, E, Neumann, P, Wilkinson, A.J, Brzozowski, A.M, Bujacz, G.D. | Deposit date: | 2006-02-08 | Release date: | 2006-02-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis of the Sulphate Starvation Response in E. coli: Crystal Structure and Mutational Analysis of the Cofactor-binding Domain of the Cbl Transcriptional Regulator. J.Mol.Biol., 364, 2006
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1MWD
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![BU of 1mwd by Molmil](/molmil-images/mine/1mwd) | WILD TYPE DEOXY MYOGLOBIN | Descriptor: | PROTEIN (MYOGLOBIN), PROTOPORPHYRIN IX CONTAINING FE | Authors: | Murshudov, G.N, Krzywda, S, Brzozowski, A.M, Jaskolski, M, Scott, E.E, Klizas, A.A, Gibson, Q.H, Olson, J.S, Wilkinson, A.J. | Deposit date: | 1998-08-11 | Release date: | 1998-08-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Stabilizing bound O2 in myoglobin by valine68 (E11) to asparagine substitution. Biochemistry, 37, 1998
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2J5G
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![BU of 2j5g by Molmil](/molmil-images/mine/2j5g) | The Native structure of a beta-Diketone Hydrolase from the Cyanobacterium Anabaena sp. PCC 7120 | Descriptor: | ALR4455 PROTEIN, SULFATE ION | Authors: | Bennett, J.P, Whittingham, J.L, Brzozowski, A.M, Leonard, P.M, Grogan, G. | Deposit date: | 2006-09-18 | Release date: | 2007-01-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Structural Characterisation of a Beta Diketone Hydrolase from the Cyanobacterium Anabaena Sp. Pcc 7120 in Native and Product Bound Forms, a Coenzyme A-Independent Member of the Crotonase Suprafamily Biochemistry, 46, 2007
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2J7Y
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![BU of 2j7y by Molmil](/molmil-images/mine/2j7y) | STRUCTURE OF 17-EPIESTRIOL-BOUND ESTROGEN RECEPTOR BETA LBD IN COMPLEX WITH LXXLL MOTIF FROM NCOA5 | Descriptor: | (16ALPHA,17ALPHA)-ESTRA-1,3,5(10)-TRIENE-3,16,17-TRIOL, 1,2-ETHANEDIOL, BICARBONATE ION, ... | Authors: | Pike, A.C.W, Brzozowski, A.M, Hubbard, R.E, Walton, J, Bonn, T, Thorsell, A.-G, Engstrom, O, Ljunggren, J, Gustaffson, J.-A, Carlquist, M. | Deposit date: | 2006-10-17 | Release date: | 2006-11-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of Agonist-Bound Estrogen Receptor Beta Lbd in Complex with Lxxll Motif from Ncoa5 To be Published
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2J5S
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![BU of 2j5s by Molmil](/molmil-images/mine/2j5s) | Structural of ABDH, a beta-diketone hydrolase from the Cyanobacterium Anabaena sp. PCC 7120 bound to (S)-3-oxocyclohexyl acetic acid | Descriptor: | (S)-CYCLOHEXANONE-2-ACETATE, BETA-DIKETONE HYDROLASE, NICKEL (II) ION | Authors: | Bennett, J.P, Whittingham, J.L, Brzozowski, A.M, Leonard, P.M, Grogan, G. | Deposit date: | 2006-09-19 | Release date: | 2007-01-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Structural Characterisation of a Beta Diketone Hydrolase from the Cyanobacterium Anabaena Sp. Pcc 7120 in Native and Product Bound Forms, a Coenzyme A-Independent Member of the Crotonase Suprafamily Biochemistry, 46, 2007
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2J5I
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![BU of 2j5i by Molmil](/molmil-images/mine/2j5i) | Crystal Structure of Hydroxycinnamoyl-CoA Hydratase-Lyase | Descriptor: | P-HYDROXYCINNAMOYL COA HYDRATASE/LYASE | Authors: | Leonard, P.M, Brzozowski, A.M, Lebedev, A, Marshall, C.M, Smith, D.J, Verma, C.S, Walton, N.J, Grogan, G. | Deposit date: | 2006-09-18 | Release date: | 2006-12-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The 1.8 A Resolution Structure of Hydroxycinnamoyl- Coenzyme a Hydratase-Lyase (Hchl) from Pseudomonas Fluorescens, an Enzyme that Catalyses the Transformation of Feruloyl-Coenzyme a to Vanillin. Acta Crystallogr.,Sect.D, 62, 2006
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1DQD
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![BU of 1dqd by Molmil](/molmil-images/mine/1dqd) | CRYSTAL STRUCTURE OF FAB HGR-2 F6, A COMPETITIVE ANTAGONIST OF THE GLUCAGON RECEPTOR | Descriptor: | FAB HGR-2 F6 | Authors: | Wright, L.M, Brzozowski, A.M, Hubbard, R.E, Pike, A.C.W, Roberts, S.M, Skovgaard, R.N, Svendsen, I, Vissing, H, Bywater, R.P. | Deposit date: | 2000-01-04 | Release date: | 2000-05-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of Fab hGR-2 F6, a competitive antagonist of the glucagon receptor. Acta Crystallogr.,Sect.D, 56, 2000
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1DYS
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![BU of 1dys by Molmil](/molmil-images/mine/1dys) | Endoglucanase CEL6B from Humicola insolens | Descriptor: | ENDOGLUCANASE | Authors: | Davies, G.J, Brzozowski, A.M, Dauter, M, Varrot, A, Schulein, M. | Deposit date: | 2000-02-08 | Release date: | 2001-02-08 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure and Function of Humicola Insolens Family 6 Cellulases: Structure of the Endoglucanase, Cel6B, at 1.6 A Resolution Biochem.J., 348, 2000
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1DT5
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![BU of 1dt5 by Molmil](/molmil-images/mine/1dt5) | |
1DU4
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![BU of 1du4 by Molmil](/molmil-images/mine/1du4) | |
1DT3
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![BU of 1dt3 by Molmil](/molmil-images/mine/1dt3) | |
1DTE
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![BU of 1dte by Molmil](/molmil-images/mine/1dte) | |
1EIN
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![BU of 1ein by Molmil](/molmil-images/mine/1ein) | |
1WAP
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![BU of 1wap by Molmil](/molmil-images/mine/1wap) | |
1A65
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![BU of 1a65 by Molmil](/molmil-images/mine/1a65) | TYPE-2 CU-DEPLETED LACCASE FROM COPRINUS CINEREUS | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, LACCASE, ... | Authors: | Ducros, V, Brzozowski, W. | Deposit date: | 1998-03-05 | Release date: | 1999-03-30 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Crystal structure of the type-2 Cu depleted laccase from Coprinus cinereus at 2.2 A resolution. Nat.Struct.Biol., 5, 1998
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2BPI
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![BU of 2bpi by Molmil](/molmil-images/mine/2bpi) | Structure of Iron dependent superoxide dismutase from P. falciparum. | Descriptor: | FE (III) ION, FE-SUPEROXIDE DISMUTASE | Authors: | Boucher, I.W, Brannigan, J, Wilkinson, A.J, Brzozowski, M. | Deposit date: | 2005-04-20 | Release date: | 2006-10-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | The Crystal Structure of Superoxide Dismutase from Plasmodium Falciparum. Bmc Struct.Biol., 6, 2006
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1QAW
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![BU of 1qaw by Molmil](/molmil-images/mine/1qaw) | Regulatory Features of the TRP Operon and the Crystal Structure of the TRP RNA-Binding Attenuation Protein from Bacillus Stearothermophilus. | Descriptor: | TRP RNA-BINDING ATTENUATION PROTEIN, TRYPTOPHAN | Authors: | Chen, X.-P, Antson, A.A, Yang, M, Baumann, C, Dodson, E.J, Dodson, G.G, Gollnick, P. | Deposit date: | 1999-03-31 | Release date: | 1999-04-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Regulatory features of the trp operon and the crystal structure of the trp RNA-binding attenuation protein from Bacillus stearothermophilus. J.Mol.Biol., 289, 1999
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5KQV
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![BU of 5kqv by Molmil](/molmil-images/mine/5kqv) | Insulin receptor ectodomain construct comprising domains L1,CR,L2, FnIII-1 and alphaCT peptide in complex with bovine insulin and FAB 83-14 (REVISED STRUCTURE) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin, Insulin receptor,Insulin receptor, ... | Authors: | Lawrence, M.C, Smith, B.J, Croll, T.I. | Deposit date: | 2016-07-06 | Release date: | 2017-07-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (4.4 Å) | Cite: | How insulin engages its primary binding site on the insulin receptor. Nature, 493, 2013
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5E98
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![BU of 5e98 by Molmil](/molmil-images/mine/5e98) | |
5E9B
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![BU of 5e9b by Molmil](/molmil-images/mine/5e9b) | Crystal structure of human heparanase in complex with HepMer M09S05a | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, CHLORIDE ION, ... | Authors: | Wu, L, Davies, G.J. | Deposit date: | 2015-10-14 | Release date: | 2015-11-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Structural characterization of human heparanase reveals insights into substrate recognition. Nat.Struct.Mol.Biol., 22, 2015
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