4RSJ
 
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4RSI
 | | Yeast Smc2-Smc4 hinge domain with extended coiled coils | | Descriptor: | PHOSPHATE ION, Structural maintenance of chromosomes protein 2, Structural maintenance of chromosomes protein 4 | | Authors: | Soh, Y.M, Shin, H.C, Oh, B.H. | | Deposit date: | 2014-11-08 | | Release date: | 2014-12-31 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Molecular Basis for SMC Rod Formation and Its Dissolution upon DNA Binding.
Mol.Cell, 57, 2015
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5JIX
 | | PKG II's Carboxyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with 8-Br-cGMP | | Descriptor: | 1,2-ETHANEDIOL, 2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-1,9-dihydro-6H-purin-6-one, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ... | | Authors: | Campbell, J.C, Kim, C.W. | | Deposit date: | 2016-04-22 | | Release date: | 2017-05-03 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.47 Å) | | Cite: | Structural Basis of Analog Specificity in PKG I and II.
ACS Chem. Biol., 12, 2017
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5J48
 | | PKG I's Carboyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with 8-pCPT-cGMP | | Descriptor: | 1,2-ETHANEDIOL, 2-amino-8-[(4-chlorophenyl)sulfanyl]-9-[(2S,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-3,9-dihydro-6H-purin-6-one, CALCIUM ION, ... | | Authors: | Campbell, J.C, Sankaran, B, Kim, C.W. | | Deposit date: | 2016-03-31 | | Release date: | 2017-04-12 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Structural Basis of Analog Specificity in PKG I and II.
ACS Chem. Biol., 12, 2017
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5JD7
 | | PKG I's Carboxyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with PET-cGMP | | Descriptor: | 3-[(2S,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-6-phenyl-3,4-dihydro-9H-imidazo[1,2-a]purin-9-one, cGMP-dependent protein kinase 1 | | Authors: | Campbell, J.C, Sankaran, B, Kim, C.W. | | Deposit date: | 2016-04-15 | | Release date: | 2017-08-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.749 Å) | | Cite: | Structural Basis of Analog Specificity in PKG I and II.
ACS Chem. Biol., 12, 2017
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5JAX
 | | PKG I's Carboyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with 8-Br-cGMP | | Descriptor: | 2-amino-8-bromo-9-[(2R,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-1,9-dihydro-6H-purin-6-one, CALCIUM ION, SODIUM ION, ... | | Authors: | Campbell, J.C, Sankaran, B, Kim, C.W. | | Deposit date: | 2016-04-12 | | Release date: | 2017-04-19 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.486 Å) | | Cite: | Structural Basis of Analog Specificity in PKG I and II.
ACS Chem. Biol., 12, 2017
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7MBJ
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7Z2K
 | | Crystal structure of SARS-CoV-2 Main Protease in orthorhombic space group p212121 | | Descriptor: | 3C-like proteinase nsp5, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | Authors: | Reinke, P.Y.A, Falke, S, Lieske, J, Ewert, W, Loboda, J, Rahmani Mashhour, A, Hauser, M, Karnicar, K, Usenik, A, Lindic, N, Lach, M, Boehler, H, Beck, T, Cox, R, Chapman, H.N, Hinrichs, W, Turk, D, Guenther, S, Meents, A. | | Deposit date: | 2022-02-28 | | Release date: | 2023-03-22 | | Last modified: | 2024-07-31 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | SARS-CoV-2 M pro responds to oxidation by forming disulfide and NOS/SONOS bonds.
Nat Commun, 15, 2024
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8C0Y
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7LV3
 | | Crystal structure of human protein kinase G (PKG) R-C complex in inhibited state | | Descriptor: | 1,2-ETHANEDIOL, Isoform Beta of cGMP-dependent protein kinase 1, MANGANESE (II) ION, ... | | Authors: | Sharma, R, Lying, Q, Casteel, D, Kim, C. | | Deposit date: | 2021-02-23 | | Release date: | 2022-08-24 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | An auto-inhibited state of protein kinase G and implications for selective activation.
Elife, 11, 2022
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7E60
 | | The crystal structure of peptidoglycan peptidase in complex with inhibitor 1 | | Descriptor: | (2~{R},6~{S})-2,6-diacetamido-7-[[(2~{R})-1-(oxidanylamino)-1-oxidanylidene-propan-2-yl]amino]-7-oxidanylidene-heptanoic acid, Peptidase M23, ZINC ION | | Authors: | Min, K, Yoon, H.J, Choi, Y, Lee, H.H. | | Deposit date: | 2021-02-21 | | Release date: | 2022-02-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | Structure-based inhibitor design for reshaping bacterial morphology
Commun Biol, 5, 2022
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7E69
 | | The crystal structure of peptidoglycan peptidase in complex with inhibitor 3-3 | | Descriptor: | N-oxidanyl-4-[(4-sulfamoylphenyl)methyl]benzamide, Peptidase M23, ZINC ION | | Authors: | Choi, Y, Min, K.J, Yoon, H.J, Lee, H.H. | | Deposit date: | 2021-02-21 | | Release date: | 2022-02-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Structure-based inhibitor design for reshaping bacterial morphology
Commun Biol, 5, 2022
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7E65
 | | The crystal structure of peptidoglycan peptidase in complex with inhibitor 3 | | Descriptor: | (2S)-2-acetamido-N-[(2R)-1-(oxidanylamino)-1-oxidanylidene-propan-2-yl]-3-(4-sulfamoylphenyl)propanamide, Peptidase M23, ZINC ION | | Authors: | Choi, Y, Min, K.J, Yoon, H.J, Lee, H.H. | | Deposit date: | 2021-02-21 | | Release date: | 2022-02-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structure-based inhibitor design for reshaping bacterial morphology
Commun Biol, 5, 2022
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7E64
 | | The crystal structure of peptidoglycan peptidase in complex with inhibitor 2-2 | | Descriptor: | 2-[[(3S)-3-acetamido-4-[[(2R)-1-(oxidanylamino)-1-oxidanylidene-propan-2-yl]amino]-4-oxidanylidene-butyl]amino]ethanoic acid, Peptidase M23, ZINC ION | | Authors: | Choi, Y, Min, K.J, Yoon, H.J, Lee, H.H. | | Deposit date: | 2021-02-21 | | Release date: | 2022-02-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure-based inhibitor design for reshaping bacterial morphology
Commun Biol, 5, 2022
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7E67
 | | The crystal structure of peptidoglycan peptidase in complex with inhibitor 3-2 | | Descriptor: | N-oxidanyl-2-[4-(4-sulfamoylphenyl)phenyl]ethanamide, Peptidase M23, ZINC ION | | Authors: | Choi, Y, Min, K.J, Yoon, H.J, Lee, H.H. | | Deposit date: | 2021-02-21 | | Release date: | 2022-02-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structure-based inhibitor design for reshaping bacterial morphology
Commun Biol, 5, 2022
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7E61
 | | The crystal structure of peptidoglycan peptidase in complex with inhibitor 2 | | Descriptor: | 2-[[(3S)-3-acetamido-4-[[(2R)-1-(oxidanylamino)-1-oxidanylidene-propan-2-yl]amino]-4-oxidanylidene-butyl]-(phenylmethyl)amino]ethanoic acid, Peptidase M23, ZINC ION | | Authors: | Min, K.J, Yoon, H.J, Choi, Y, Lee, H.H. | | Deposit date: | 2021-02-21 | | Release date: | 2022-02-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure-based inhibitor design for reshaping bacterial morphology
Commun Biol, 5, 2022
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7E63
 | | The crystal structure of peptidoglycan peptidase in complex with inhibitor 2-1 | | Descriptor: | 2-[[(3S)-3-acetamido-4-[[(2R)-1-(oxidanylamino)-1-oxidanylidene-propan-2-yl]amino]-4-oxidanylidene-butyl]-(cyclopentylmethyl)amino]ethanoic acid, Peptidase M23, ZINC ION | | Authors: | Choi, Y, Min, K.J, Yoon, H.J, Lee, H.H. | | Deposit date: | 2021-02-21 | | Release date: | 2022-02-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure-based inhibitor design for reshaping bacterial morphology
Commun Biol, 5, 2022
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7E66
 | | The crystal structure of peptidoglycan peptidase in complex with inhibitor 3-1 | | Descriptor: | N-[2-(oxidanylamino)-2-oxidanylidene-ethyl]-2-(4-sulfamoylphenyl)ethanamide, Peptidase M23, ZINC ION | | Authors: | Choi, Y, Min, K.J, Yoon, H.J, Lee, H.H. | | Deposit date: | 2021-02-21 | | Release date: | 2022-02-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.84 Å) | | Cite: | Structure-based inhibitor design for reshaping bacterial morphology
Commun Biol, 5, 2022
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4O6G
 | | Rv3902c from M. tuberculosis | | Descriptor: | Uncharacterized protein | | Authors: | Reddy, B.G, Moates, D.B, Kim, H, Green, T.J, Kim, C, Terwilliger, T.J, Delucas, L.J, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2013-12-20 | | Release date: | 2014-03-05 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | 1.55 angstrom resolution X-ray crystal structure of Rv3902c from Mycobacterium tuberculosis.
Acta Crystallogr F Struct Biol Commun, 70, 2014
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8G5V
 | | Empty capsid of Hepatitis B virus | | Descriptor: | Core protein Cp183 | | Authors: | Yang, R, Cingolani, G. | | Deposit date: | 2023-02-14 | | Release date: | 2024-01-24 | | Last modified: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core.
Sci Adv, 10, 2024
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8G6V
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8G8Y
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8GCN
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7QA1
 | | The structure of natural crystals of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated using serial femtosecond crystallography at an X-ray free electron laser | | Descriptor: | Toxin-10 pesticidal protein (Tpp) 49Aa1 | | Authors: | Williamson, L.J, Rizkallah, P.J, Berry, C, Oberthur, D, Galchenkova, M, Yefanov, O, Bean, R, Best, H.L. | | Deposit date: | 2021-11-15 | | Release date: | 2023-05-17 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated from natural crystals using MHz-SFX.
Proc.Natl.Acad.Sci.USA, 120, 2023
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3IIA
 | | Crystal structure of apo (91-244) RIa subunit of cAMP-dependent protein kinase | | Descriptor: | GLYCEROL, cAMP-dependent protein kinase type I-alpha regulatory subunit | | Authors: | Sjoberg, T.J, Kim, C, Kornev, A.P, Taylor, S.S. | | Deposit date: | 2009-07-31 | | Release date: | 2010-08-11 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: conformational selection highlights a new concept in allosteric inhibitor design.
Mol.Cell Proteomics, 10, 2011
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