8YP3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yp3 by Molmil](/molmil-images/mine/8yp3) | Crystal structure of UDP-N-acetylglucosamine pyrophosphorylase from Spodoptera frugiperda in complex with UDP-GlcNAc | Descriptor: | MAGNESIUM ION, SULFATE ION, UDP-N-acetylglucosamine diphosphorylase, ... | Authors: | Lu, Q, Liu, T, Zhou, Y, Yang, Q. | Deposit date: | 2024-03-15 | Release date: | 2024-08-07 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Structure and Inhibition of Insect UDP- N -acetylglucosamine Pyrophosphorylase: A Key Enzyme in the Hexosamine Biosynthesis Pathway. J.Agric.Food Chem., 2024
|
|
4V60
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v60 by Molmil](/molmil-images/mine/4v60) | The structure of rat liver vault at 3.5 angstrom resolution | Descriptor: | Major vault protein | Authors: | Kato, K, Zhou, Y, Tanaka, H, Yao, M, Yamashita, E, Yoshimura, M, Tsukihara, T. | Deposit date: | 2008-10-24 | Release date: | 2014-07-09 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | The structure of rat liver vault at 3.5 angstrom resolution Science, 323, 2009
|
|
6INW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6inw by Molmil](/molmil-images/mine/6inw) | A Pericyclic Reaction enzyme | Descriptor: | O-methyltransferase lepI, S-ADENOSYLMETHIONINE | Authors: | Feng, Y, Chang, M, Wang, H, Liu, Z, Zhou, Y. | Deposit date: | 2018-10-28 | Release date: | 2019-07-03 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | Crystal structure of the multifunctional SAM-dependent enzyme LepI provides insights into its catalytic mechanism. Biochem.Biophys.Res.Commun., 515, 2019
|
|
3ZJV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zjv by Molmil](/molmil-images/mine/3zjv) | Ternary complex of E .coli leucyl-tRNA synthetase, tRNA(Leu) and the benzoxaborole AN3213 in the editing conformation | Descriptor: | LEUCINE--TRNA LIGASE, TRNALEU5 UAA ISOACCEPTOR | Authors: | Cusack, S, Palencia, A, Crepin, T, Hernandez, V, Akama, T, Baker, S.J, Bu, W, Feng, L, Freund, Y.R, Liu, L, Meewan, M, Mohan, M, Mao, W, Rock, F.L, Sexton, H, Sheoran, A, Zhang, Y, Zhang, Y, Zhou, Y, Nieman, J.A, Anugula, M.R, Keramane, E.M, Savariraj, K, Reddy, D.S, Sharma, R, Subedi, R, Singh, R, OLeary, A, Simon, N.L, DeMarsh, P.L, Mushtaq, S, Warner, M, Livermore, D.M, Alley, M.R.K, Plattner, J.J. | Deposit date: | 2013-01-18 | Release date: | 2013-04-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria. Antimicrob.Agents Chemother., 57, 2013
|
|
3ZJU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zju by Molmil](/molmil-images/mine/3zju) | Ternary complex of E .coli leucyl-tRNA synthetase, tRNA(Leu) and the benzoxaborole AN3016 in the editing conformation | Descriptor: | LEUCYL-TRNA SYNTHETASE, MAGNESIUM ION, TRNALEU5 UAA ISOACCEPTOR | Authors: | Cusack, S, Palencia, A, Crepin, T, Hernandez, V, Akama, T, Baker, S.J, Bu, W, Feng, L, Freund, Y.R, Liu, L, Meewan, M, Mohan, M, Mao, W, Rock, F.L, Sexton, H, Sheoran, A, Zhang, Y, Zhang, Y, Zhou, Y, Nieman, J.A, Anugula, M.R, Keramane, E.M, Savariraj, K, Reddy, D.S, Sharma, R, Subedi, R, Singh, R, OLeary, A, Simon, N.L, DeMarsh, P.L, Mushtaq, S, Warner, M, Livermore, D.M, Alley, M.R.K, Plattner, J.J. | Deposit date: | 2013-01-18 | Release date: | 2013-04-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria. Antimicrob.Agents Chemother., 57, 2013
|
|
3ZJT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zjt by Molmil](/molmil-images/mine/3zjt) | Ternary complex of E.coli leucyl-tRNA synthetase, tRNA(Leu)574 and the benzoxaborole AN3017 in the editing conformation | Descriptor: | LEUCYL-TRNA SYNTHETASE, MAGNESIUM ION, TRNALEU5 UAA ISOACCEPTOR | Authors: | Cusack, S, Palencia, A, Crepin, T, Hernandez, V, Akama, T, Baker, S.J, Bu, W, Feng, L, Freund, Y.R, Liu, L, Meewan, M, Mohan, M, Mao, W, Rock, F.L, Sexton, H, Sheoran, A, Zhang, Y, Zhang, Y, Zhou, Y, Nieman, J.A, Anugula, M.R, Keramane, E.M, Savariraj, K, Reddy, D.S, Sharma, R, Subedi, R, Singh, R, OLeary, A, Simon, N.L, DeMarsh, P.L, Mushtaq, S, Warner, M, Livermore, D.M, Alley, M.R.K, Plattner, J.J. | Deposit date: | 2013-01-18 | Release date: | 2013-04-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria. Antimicrob.Agents Chemother., 57, 2013
|
|
5N16
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n16 by Molmil](/molmil-images/mine/5n16) | First Bromodomain (BD1) from Candida albicans Bdf1 bound to a dibenzothiazepinone (compound 1) | Descriptor: | 5-cyclopropyl-2-(5-pyrazin-2-yl-1,2,4-oxadiazol-3-yl)benzo[b][1,4]benzothiazepin-6-one, Bromodomain-containing factor 1, GLYCEROL, ... | Authors: | Mietton, F, Ferri, E, Champleboux, M, Zala, N, Maubon, D, Zhou, Y, Harbut, M, Spittler, D, Garnaud, C, Courcon, M, Chauvel, M, d'Enfert, C, Kashemirov, B.A, Hull, M, Cornet, M, McKenna, C.E, Govin, J, Petosa, C. | Deposit date: | 2017-02-05 | Release date: | 2017-05-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Selective BET bromodomain inhibition as an antifungal therapeutic strategy. Nat Commun, 8, 2017
|
|
5N15
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n15 by Molmil](/molmil-images/mine/5n15) | First Bromodomain (BD1) from Candida albicans Bdf1 in the unbound form | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bromodomain-containing factor 1, GLYCEROL, ... | Authors: | Mietton, F, Ferri, E, Champleboux, M, Zala, N, Maubon, D, Zhou, Y, Harbut, M, Spittler, D, Garnaud, C, Courcon, M, Chauvel, M, d'Enfert, C, Kashemirov, B.A, Hull, M, Cornet, M, McKenna, C.E, Govin, J, Petosa, C. | Deposit date: | 2017-02-05 | Release date: | 2017-05-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Selective BET bromodomain inhibition as an antifungal therapeutic strategy. Nat Commun, 8, 2017
|
|
5N18
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n18 by Molmil](/molmil-images/mine/5n18) | Second Bromodomain (BD2) from Candida albicans Bdf1 bound to an imidazopyridine (compound 2) | Descriptor: | 4-[8-methyl-3-[(4-methylphenyl)amino]imidazo[1,2-a]pyridin-2-yl]phenol, Bromodomain-containing factor 1, GLYCEROL | Authors: | Mietton, F, Ferri, E, Champleboux, M, Zala, N, Maubon, D, Zhou, Y, Harbut, M, Spittler, D, Garnaud, C, Courcon, M, Chauvel, M, d'Enfert, C, Kashemirov, B.A, Hull, M, Cornet, M, McKenna, C.E, Govin, J, Petosa, C. | Deposit date: | 2017-02-05 | Release date: | 2017-05-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Selective BET bromodomain inhibition as an antifungal therapeutic strategy. Nat Commun, 8, 2017
|
|
5N13
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n13 by Molmil](/molmil-images/mine/5n13) | Second Bromodomain (BD2) from Candida albicans Bdf1 in the unbound form | Descriptor: | Bromodomain-containing factor 1, GLYCEROL | Authors: | Mietton, F, Ferri, E, Champlebouxm, M, Zala, N, Maubon, D, Zhou, Y, Harbut, M, Spittler, D, Garnaud, C, Courcon, M, Chauvel, M, d'Enfert, C, Kashemirov, B.A, Hull, M, Cornet, M, McKenna, C.E, Govin, J, Petosa, C. | Deposit date: | 2017-02-04 | Release date: | 2017-05-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Selective BET bromodomain inhibition as an antifungal therapeutic strategy. Nat Commun, 8, 2017
|
|
5N17
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n17 by Molmil](/molmil-images/mine/5n17) | First Bromodomain (BD1) from Candida albicans Bdf1 bound to a dibenzothiazepinone (compound 3) | Descriptor: | (2~{S})-~{N}-(5-methyl-6-oxidanylidene-benzo[b][1,4]benzothiazepin-2-yl)oxolane-2-carboxamide, Bromodomain-containing factor 1, SULFATE ION | Authors: | Mietton, F, Ferri, E, Champleboux, M, Zala, N, Maubon, D, Zhou, Y, Harbut, M, Spittler, D, Garnaud, C, Courcon, M, Chauvon, M, d'Enfer, C, Kashemirov, B.A, Hull, M, Cornet, M, McKenna, C.E, Govin, J, Petosa, C. | Deposit date: | 2017-02-05 | Release date: | 2017-05-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Selective BET bromodomain inhibition as an antifungal therapeutic strategy. Nat Commun, 8, 2017
|
|
1IJL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ijl by Molmil](/molmil-images/mine/1ijl) | Crystal structure of acidic phospholipase A2 from deinagkistrodon acutus | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2, ZINC ION | Authors: | Gu, L, Zhang, H, Song, S, Zhou, Y, Lin, Z. | Deposit date: | 2001-04-27 | Release date: | 2001-12-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of an acidic phospholipase A2 from the venom of Deinagkistrodon acutus. Acta Crystallogr.,Sect.D, 58, 2002
|
|
1C1J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1c1j by Molmil](/molmil-images/mine/1c1j) | STRUCTURE OF CADMIUM-SUBSTITUTED PHOSPHOLIPASE A2 FROM AGKISTRONDON HALYS PALLAS AT 2.8 ANGSTROMS RESOLUTION | Descriptor: | BASIC PHOSPHOLIPASE A2, CADMIUM ION, octyl beta-D-glucopyranoside | Authors: | Zhang, H.-l, Zhang, Y.-q, Song, S.-y, Zhou, Y, Lin, Z.-j. | Deposit date: | 1999-07-22 | Release date: | 2002-07-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of Cadmium-substituted Phospholipase A2 from Agkistrodon halys
Pallas at 2.8 Angstroms Resolution Protein Pept.Lett., 6, 1999
|
|
5Y2B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y2b by Molmil](/molmil-images/mine/5y2b) | Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 in complex with HEPTA-N-ACETYLCHITOOCTAOSE (NAG)7 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, insect group II chitinase | Authors: | Chen, W, Qu, M.B, Zhou, Y, Yang, Q. | Deposit date: | 2017-07-24 | Release date: | 2018-01-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects J. Biol. Chem., 293, 2018
|
|
6PDX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pdx by Molmil](/molmil-images/mine/6pdx) | |
4M7D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m7d by Molmil](/molmil-images/mine/4m7d) | Crystal structure of Lsm2-8 complex bound to the RNA fragment CGUUU | Descriptor: | U6 snRNA, U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, ... | Authors: | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | Deposit date: | 2013-08-12 | Release date: | 2013-11-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.595 Å) | Cite: | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
|
|
4M75
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m75 by Molmil](/molmil-images/mine/4m75) | Crystal structure of Lsm1-7 complex | Descriptor: | CHLORIDE ION, U6 snRNA-associated Sm-like protein Lsm1, U6 snRNA-associated Sm-like protein Lsm2, ... | Authors: | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | Deposit date: | 2013-08-12 | Release date: | 2013-10-23 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
|
|
4M77
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m77 by Molmil](/molmil-images/mine/4m77) | Crystal structure of Lsm2-8 complex, space group I212121 | Descriptor: | U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, U6 snRNA-associated Sm-like protein LSm4, ... | Authors: | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | Deposit date: | 2013-08-12 | Release date: | 2013-11-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.111 Å) | Cite: | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
|
|
4M78
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m78 by Molmil](/molmil-images/mine/4m78) | Crystal structure of Lsm2-8 complex, space group P21 | Descriptor: | U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, U6 snRNA-associated Sm-like protein LSm4, ... | Authors: | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | Deposit date: | 2013-08-12 | Release date: | 2013-11-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.794 Å) | Cite: | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
|
|
4M7A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m7a by Molmil](/molmil-images/mine/4m7a) | Crystal structure of Lsm2-8 complex bound to the 3' end sequence of U6 snRNA | Descriptor: | U6 snRNA, U6 snRNA-associated Sm-like protein LSm2, U6 snRNA-associated Sm-like protein LSm3, ... | Authors: | Zhou, L, Hang, J, Zhou, Y, Wan, R, Lu, G, Yan, C, Shi, Y. | Deposit date: | 2013-08-12 | Release date: | 2013-11-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.781 Å) | Cite: | Crystal structures of the Lsm complex bound to the 3' end sequence of U6 small nuclear RNA. Nature, 506, 2014
|
|
5JDB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jdb by Molmil](/molmil-images/mine/5jdb) | Binding specificity of P[8] VP8* proteins of rotavirus vaccine strains with histo-blood group antigens | Descriptor: | Outer capsid protein VP4 | Authors: | Sun, X, Guo, N, Li, D, Zhou, Y, Jin, M, Xie, G, Pang, L, Zhang, Q, Cao, Y, Duan, Z. | Deposit date: | 2016-04-16 | Release date: | 2016-07-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Binding specificity of P[8] VP8* proteins of rotavirus vaccine strains with histo-blood group antigens. Virology, 495, 2016
|
|
6GHM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ghm by Molmil](/molmil-images/mine/6ghm) | Structure of PP1 alpha phosphatase bound to ASPP2 | Descriptor: | 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Apoptosis-stimulating of p53 protein 2, ... | Authors: | Mouilleron, S, Bertran, T.M, Tapon, N, Zhou, Y. | Deposit date: | 2018-05-08 | Release date: | 2019-02-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail. Nat Commun, 10, 2019
|
|
6IGY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6igy by Molmil](/molmil-images/mine/6igy) | |
8C9M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8c9m by Molmil](/molmil-images/mine/8c9m) | HERV-K Gag immature lattice | Descriptor: | Gag protein | Authors: | Krebs, A.-S, Liu, H.-F, Zhou, Y, Rey, J.S, Levintov, L, Perilla, J.R, Bartesaghi, A, Zhang, P. | Deposit date: | 2023-01-23 | Release date: | 2023-02-01 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular architecture and conservation of an immature human endogenous retrovirus. Biorxiv, 2023
|
|
3WNV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wnv by Molmil](/molmil-images/mine/3wnv) | Crystal structure of a glyoxylate reductase from Paecilomyes thermophila | Descriptor: | SULFATE ION, glyoxylate reductase | Authors: | Duan, X, Hu, S, Zhou, P, Zhou, Y, Jiang, Z. | Deposit date: | 2013-12-17 | Release date: | 2014-12-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Characterization and crystal structure of a first fungal glyoxylate reductase from Paecilomyes thermophila Enzyme.Microb.Technol., 60, 2014
|
|