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6LUQ
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BU of 6luq by Molmil
Haloperidol bound D2 dopamine receptor structure inspired discovery of subtype selective ligands
Descriptor: 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one, OLEIC ACID, chimera of D(2) dopamine receptor and Endolysin
Authors:Fan, L, Tan, L, Chen, Z, Qi, J, Nie, F, Luo, Z, Cheng, J, Wang, S.
Deposit date:2020-01-30
Release date:2020-03-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Haloperidol bound D2dopamine receptor structure inspired the discovery of subtype selective ligands.
Nat Commun, 11, 2020
4L6Y
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BU of 4l6y by Molmil
Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1)
Descriptor: Protein regulator of cytokinesis 1
Authors:Subramanian, R, Ti, S, Tan, L, Darst, S.A, Kapoor, T.M.
Deposit date:2013-06-13
Release date:2013-07-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.3015 Å)
Cite:Marking and Measuring Single Microtubules by PRC1 and Kinesin-4.
Cell(Cambridge,Mass.), 154, 2013
4L3I
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BU of 4l3i by Molmil
Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1)
Descriptor: Protein regulator of cytokinesis 1
Authors:Subramanian, R, Ti, S, Tan, L, Darst, S.A, Kapoor, T.M.
Deposit date:2013-06-06
Release date:2013-07-17
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (3.6005 Å)
Cite:Marking and Measuring Single Microtubules by PRC1 and Kinesin-4.
Cell(Cambridge,Mass.), 154, 2013
7F6J
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BU of 7f6j by Molmil
Crystal structure of the PDZD8 coiled-coil domain - Rab7 complex
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PDZ domain-containing protein 8, ...
Authors:Khan, H, Chen, L, Tan, L, Im, Y.J.
Deposit date:2021-06-25
Release date:2022-02-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of human PDZD8-Rab7 interaction for the ER-late endosome tethering.
Sci Rep, 11, 2021
7WWG
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BU of 7wwg by Molmil
Crystal structure of Saccharomyces cerevisiae Sfh2 complexed with phosphatidylinositol in an open conformation
Descriptor: (1R)-2-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Phosphatidylinositol transfer protein CSR1
Authors:Chen, L, Tan, L, Im, Y.J.
Deposit date:2022-02-12
Release date:2022-07-13
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis of ligand recognition and transport by Sfh2, a yeast phosphatidylinositol transfer protein of the Sec14 superfamily.
Acta Crystallogr D Struct Biol, 78, 2022
7WWD
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Crystal structure of Saccharomyces cerevisiae Sfh2 complexed with squalene
Descriptor: (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene, Phosphatidylinositol transfer protein CSR1
Authors:Chen, L, Tan, L, Im, Y.J.
Deposit date:2022-02-12
Release date:2022-07-13
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structural basis of ligand recognition and transport by Sfh2, a yeast phosphatidylinositol transfer protein of the Sec14 superfamily.
Acta Crystallogr D Struct Biol, 78, 2022
7WWE
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BU of 7wwe by Molmil
Crystal structure of Saccharomyces cerevisiae Sfh2 in an apo form
Descriptor: Phosphatidylinositol transfer protein CSR1
Authors:Chen, L, Tan, L, Im, Y.J.
Deposit date:2022-02-12
Release date:2022-07-13
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of ligand recognition and transport by Sfh2, a yeast phosphatidylinositol transfer protein of the Sec14 superfamily.
Acta Crystallogr D Struct Biol, 78, 2022
7WVT
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BU of 7wvt by Molmil
Crystal structure of Saccharomyces cerevisiae Sfh2 complexed with phosphatidylinositol
Descriptor: (1R)-2-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Phosphatidylinositol transfer protein CSR1
Authors:Chen, L, Tan, L, Im, Y.J.
Deposit date:2022-02-11
Release date:2022-07-13
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of ligand recognition and transport by Sfh2, a yeast phosphatidylinositol transfer protein of the Sec14 superfamily.
Acta Crystallogr D Struct Biol, 78, 2022
7DEJ
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BU of 7dej by Molmil
Structure of human ORP3 ORD in apo-form
Descriptor: Oxysterol-binding protein-related protein 3
Authors:Tong, J, Tan, L, Im, Y.J.
Deposit date:2020-11-04
Release date:2021-03-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of human ORP3 ORD reveals conservation of a key function and ligand specificity in OSBP-related proteins.
Plos One, 16, 2021
7DEI
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BU of 7dei by Molmil
Structure of human ORP3 ORD domain in complex with PI(4)P
Descriptor: (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, Oxysterol-binding protein-related protein 3
Authors:Tong, J, Tan, L, Im, Y.J.
Deposit date:2020-11-04
Release date:2021-03-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of human ORP3 ORD reveals conservation of a key function and ligand specificity in OSBP-related proteins.
Plos One, 16, 2021
5SBI
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BU of 5sbi by Molmil
The crystal structure of METP in complex with Co at a resolution of 1.80A.
Descriptor: COBALT (II) ION, METP, miniaturized rubredoxin
Authors:Di Costanzo, L, La Gatta, S, Leone, L, Chino, M.
Deposit date:2021-08-24
Release date:2023-02-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Miniaturization process reloaded - structural and functional insights from a miniaturized rubredoxin
To be published
5SBJ
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BU of 5sbj by Molmil
The crystal structure of METP in complex with Cd at a resolution of 1.29 A.
Descriptor: CADMIUM ION, METP, miniaturized rubredoxin
Authors:Di Costanzo, L, La Gatta, S, Pavone, V.
Deposit date:2021-08-24
Release date:2023-02-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Miniaturization process reloaded - structural and functional insights from a miniaturized rubredoxin
To be published
1OVU
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BU of 1ovu by Molmil
CRYSTAL STRUCTURE OF FOUR-HELIX BUNDLE MODEL di-Co(II)-DF1-L13A (form I)
Descriptor: COBALT (II) ION, four-helix bundle model di-Co(II)-DF1-L13A (form I)
Authors:Di Costanzo, L, Geremia, S.
Deposit date:2003-03-27
Release date:2004-04-06
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Response of a designed metalloprotein to changes in metal ion coordination, exogenous ligands, and active site volume determined by X-ray crystallography.
J.Am.Chem.Soc., 127, 2005
3G9V
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BU of 3g9v by Molmil
Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22
Descriptor: Interleukin 22 receptor, alpha 2, Interleukin-22
Authors:de Moura, P.R, Watanabe, L, Bleicher, L, Colau, D, Renauld, J.-C, Polikarpov, I.
Deposit date:2009-02-14
Release date:2009-04-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.756 Å)
Cite:Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22
FEBS Lett., 583, 2009
3DLQ
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BU of 3dlq by Molmil
Crystal structure of the IL-22/IL-22R1 complex
Descriptor: Interleukin-22, Interleukin-22 receptor subunit alpha-1
Authors:Bleicher, L, de Moura, P.R, Watanabe, L, Colau, D, Dumoutier, L, Renauld, J.-C, Polikarpov, I.
Deposit date:2008-06-28
Release date:2008-08-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the IL-22/IL-22R1 complex and its implications for the IL-22 signaling mechanism
Febs Lett., 582, 2008
3EOP
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BU of 3eop by Molmil
Crystal Structure of the DUF55 domain of human thymocyte nuclear protein 1
Descriptor: SULFATE ION, Thymocyte nuclear protein 1
Authors:Yu, F, Song, A, Xu, C, Sun, L, Li, L, Tang, L, Hu, H, He, J.
Deposit date:2008-09-29
Release date:2009-09-29
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Determining the DUF55-domain structure of human thymocyte nuclear protein 1 from crystals partially twinned by tetartohedry
Acta Crystallogr.,Sect.D, 65, 2009
1OVV
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BU of 1ovv by Molmil
CRYSTAL STRUCTURE OF FOUR-HELIX BUNDLE MODEL di-Co(II)-DF1-L13A (form II)
Descriptor: COBALT (II) ION, FOUR-HELIX BUNDLE MODEL di-Co(II)-DF1-L13A (form II)
Authors:Di Costanzo, L, Geremia, S.
Deposit date:2003-03-27
Release date:2004-04-06
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Response of a designed metalloprotein to changes in metal ion coordination, exogenous ligands, and active site volume determined by X-ray crystallography.
J.Am.Chem.Soc., 127, 2005
3NB3
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BU of 3nb3 by Molmil
The host outer membrane proteins OmpA and OmpC are packed at specific sites in the Shigella phage Sf6 virion as structural components
Descriptor: Outer membrane protein A, Outer membrane protein C
Authors:Zhao, H, Sequeira, R.D, Galeva, N.A, Tang, L.
Deposit date:2010-06-02
Release date:2011-02-16
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (19 Å)
Cite:The host outer membrane proteins OmpA and OmpC are associated with the Shigella phage Sf6 virion.
Virology, 409, 2011
5L35
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BU of 5l35 by Molmil
Cryo-EM structure of bacteriophage Sf6 at 2.9 Angstrom resolution
Descriptor: CHLORIDE ION, Gene 5 protein
Authors:Zhao, H, Tang, L.
Deposit date:2016-08-03
Release date:2017-03-22
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Structure of a headful DNA-packaging bacterial virus at 2.9 angstrom resolution by electron cryo-microscopy.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1OVR
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BU of 1ovr by Molmil
CRYSTAL STRUCTURE OF FOUR-HELIX BUNDLE MODEL di-Mn(II)-DF1-L13
Descriptor: MANGANESE (II) ION, four-helix bundle model di-Mn(II)-DF1-L13
Authors:Di Costanzo, L, Geremia, S.
Deposit date:2003-03-27
Release date:2004-05-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Response of a designed metalloprotein to changes in metal ion coordination, exogenous ligands, and active site volume determined by X-ray crystallography.
J.Am.Chem.Soc., 127, 2005
3E6K
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BU of 3e6k by Molmil
X-ray structure of Human Arginase I: the mutant D183A in complex with ABH
Descriptor: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase-1, MANGANESE (II) ION
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2008-08-15
Release date:2008-12-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Probing the specificity determinants of amino acid recognition by arginase.
Biochemistry, 48, 2009
3KV2
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BU of 3kv2 by Molmil
HIGH RESOLUTION STRUCTURE OF HUMAN ARGINASE I IN COMPLEX WITH THE STRONG INHIBITOR N(omega)-hydroxy-nor-L-arginine (nor-NOHA)
Descriptor: Arginase-1, MANGANESE (II) ION, NOR-N-OMEGA-HYDROXY-L-ARGININE
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2009-11-28
Release date:2009-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Inhibition of human arginase I by substrate and product analogues.
Arch.Biochem.Biophys., 496, 2010
6Q50
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BU of 6q50 by Molmil
Structure of MPT-4, a mannose phosphorylase from Leishmania mexicana, in complex with phosphate ion
Descriptor: 1,2-ETHANEDIOL, MPT-4, PHOSPHATE ION, ...
Authors:Sobala, L.F, Males, A, Bastidas, L.M, Ward, T, Sernee, M.F, Ralton, J.E, Nero, T.L, Cobbold, S, Kloehn, J, Viera-Lara, M, Stanton, L, Hanssen, E, Parker, M.W, Williams, S.J, McConville, M.J, Davies, G.J.
Deposit date:2018-12-06
Release date:2019-09-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites.
Cell Host Microbe, 26, 2019
3LP7
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BU of 3lp7 by Molmil
Crystal structure of Human Arginase I in complex with inhibitor N(omega)-hydroxy-L-arginine (NOHA), 2.04A Resolution
Descriptor: Arginase-1, MANGANESE (II) ION, N-OMEGA-HYDROXY-L-ARGININE
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2010-02-04
Release date:2010-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Inhibition of human arginase I by substrate and product analogues.
Arch.Biochem.Biophys., 496, 2010
2XQL
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BU of 2xql by Molmil
Fitting of the H2A-H2B histones in the electron microscopy map of the complex Nucleoplasmin:H2A-H2B histones (1:5).
Descriptor: HISTONE H2A-IV, HISTONE H2B 5
Authors:Ramos, I, Martin-Benito, J, Finn, R, Bretana, L, Aloria, K, Arizmendi, J.M, Ausio, J, Muga, A, Valpuesta, J.M, Prado, A.
Deposit date:2010-09-02
Release date:2010-11-03
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (19.5 Å)
Cite:Nucleoplasmin Binds Histone H2A-H2B Dimers Through its Distal Face.
J.Biol.Chem., 285, 2010

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