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2QEQ
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BU of 2qeq by Molmil
Crystal structure of kunjin virus ns3 helicase
Descriptor: Flavivirin protease NS3 catalytic subunit
Authors:Milani, M, Mastrangelo, E, Bolognesi, M.
Deposit date:2007-06-26
Release date:2007-08-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein
J.Mol.Biol., 372, 2007
2FAV
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BU of 2fav by Molmil
Crystal structure of SARS macro domain in complex with ADP-ribose at 1.8 A resolution
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, Replicase polyprotein 1ab (pp1ab) (ORF1AB)
Authors:Egloff, M.P, Malet, H, Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2005-12-08
Release date:2006-10-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional basis for ADP-ribose and poly(ADP-ribose) binding by viral macro domains.
J.Virol., 80, 2006
3ELY
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BU of 3ely by Molmil
Wesselsbron virus Methyltransferase in complex with AdoHcy
Descriptor: DI(HYDROXYETHYL)ETHER, Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Bollati, M, Milani, M, Ricagno, S, Mastrangelo, E, Bolognesi, M.
Deposit date:2008-09-23
Release date:2008-11-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus
J.Mol.Biol., 385, 2009
3EMB
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BU of 3emb by Molmil
Wesselsbron virus Methyltransferase in complex with AdoMet and 7MeGpppG
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Methyltransferase, S-ADENOSYLMETHIONINE, ...
Authors:Bollati, M, Ricagno, S, Milani, M, Mastrangelo, E, Bolognesi, M.
Deposit date:2008-09-24
Release date:2008-11-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus
J.Mol.Biol., 385, 2009
3ELW
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BU of 3elw by Molmil
Wesselsbron virus Methyltransferase in complex with AdoMet and GpppG
Descriptor: DIGUANOSINE-5'-TRIPHOSPHATE, Methyltransferase, S-ADENOSYLMETHIONINE, ...
Authors:Bollati, M, Ricagno, S, Milani, M, Mastrangelo, E, Bolognesi, M.
Deposit date:2008-09-23
Release date:2008-11-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus
J.Mol.Biol., 385, 2009
5M5B
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BU of 5m5b by Molmil
Crystal structure of Zika virus NS5 methyltransferase
Descriptor: CHLORIDE ION, GLYCEROL, NS5 methyltransferase, ...
Authors:Barral, K, Ortiz Lombardia, M, Coutard, B, Decroly, E, Lichiere, J.
Deposit date:2016-10-21
Release date:2016-12-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives.
J. Virol., 91, 2017
3ELU
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BU of 3elu by Molmil
Wesselsbron virus Methyltransferase in complex with AdoMet
Descriptor: Methyltransferase, S-ADENOSYLMETHIONINE, SULFATE ION
Authors:Bollati, M, Ricagno, S, Milani, M, Mastrangelo, E, Bolognesi, M.
Deposit date:2008-09-23
Release date:2008-11-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus
J.Mol.Biol., 385, 2009
3EMD
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BU of 3emd by Molmil
Wesselsbron virus Methyltransferase in complex with Sinefungin and 7MeGpppA
Descriptor: P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, SINEFUNGIN, SULFATE ION, ...
Authors:Bollati, M, Milani, M, Ricagno, S, Mastrangelo, E, Bolognesi, M.
Deposit date:2008-09-24
Release date:2008-11-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus
J.Mol.Biol., 385, 2009
3ELD
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BU of 3eld by Molmil
Wesselsbron methyltransferase in complex with Sinefungin
Descriptor: Methyltransferase, SINEFUNGIN, SULFATE ION
Authors:Bollati, M, Milani, M, Mastrangelo, E, Ricagno, S, Bolognesi, M.
Deposit date:2008-09-22
Release date:2008-11-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus
J.Mol.Biol., 385, 2009
2HCS
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BU of 2hcs by Molmil
Crystal structure of RNA dependant RNA polymerase domain of West Nile virus
Descriptor: RNA-directed RNA polymerase (NS5), ZINC ION
Authors:Egloff, M.P, Malet, H, Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2006-06-18
Release date:2007-02-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
J.Biol.Chem., 282, 2007
2HFZ
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BU of 2hfz by Molmil
Crystal structure of RNA dependent RNA polymerase domain from West Nile virus
Descriptor: MAGNESIUM ION, RNA-directed RNA polymerase(NS5), ZINC ION
Authors:Egloff, M.P, Malet, H, Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2006-06-26
Release date:2007-02-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
J.Biol.Chem., 282, 2007
2HCN
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BU of 2hcn by Molmil
Crystal structure of RNA dependent RNA polymerase domain from west nile virus
Descriptor: CALCIUM ION, RNA-directed RNA polymerase (NS5), ZINC ION
Authors:Egloff, M.P, Malet, H, Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2006-06-17
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
J.Biol.Chem., 282, 2007
6QZU
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BU of 6qzu by Molmil
Getah virus macro domain
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Non-structural polyprotein
Authors:Ferreira Ramos, A.S, Sulzenbacher, G, Coutard, B.
Deposit date:2019-03-12
Release date:2020-04-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography.
Sci Rep, 10, 2020
6R0G
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BU of 6r0g by Molmil
Getah virus macro domain in complex with ADPr, pose 2
Descriptor: ACETATE ION, ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural polyprotein
Authors:Sulzenbacher, G, Ferreira Ramos, A.S, Coutard, B.
Deposit date:2019-03-12
Release date:2020-04-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography.
Sci Rep, 10, 2020
6R0P
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BU of 6r0p by Molmil
Getah virus macro domain in complex with ADPr in double open conformation
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Non-structural polyprotein, ...
Authors:Sulzenbacher, G, Ferreira Ramos, A.S, Coutard, B.
Deposit date:2019-03-13
Release date:2020-04-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography.
Sci Rep, 10, 2020
6R0F
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BU of 6r0f by Molmil
Getah virus macro domain in complex with ADPr, pose 1
Descriptor: Non-structural polyprotein, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
Authors:Sulzenbacher, G, Ferreira Ramos, A.S, Coutard, B.
Deposit date:2019-03-12
Release date:2020-04-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography.
Sci Rep, 10, 2020
5MQX
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BU of 5mqx by Molmil
NMR solution structure of macro domain from Venezuelan equine encephalitis virus(VEEV) in complex with ADP-ribose
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural protein3
Authors:Makrynitsa, G.I, Ntonti, D, Marousis, K.D, Matsoukas, M.T, Papageorgiou, N, Coutard, B, Bentrop, D, Spyroulias, G.A.
Deposit date:2016-12-21
Release date:2018-07-04
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Conformational plasticity of the VEEV macro domain is important for binding of ADP-ribose.
J.Struct.Biol., 206, 2019
6S3A
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BU of 6s3a by Molmil
Coxsackie B3 2C protein in complex with S-Fluoxetine
Descriptor: (3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, 2C protein, CHLORIDE ION, ...
Authors:El Kazzi, P, Papageorgiou, N, Ferron, F.P, Bauer, L, van Kuppeveld, F, Coutard, B.
Deposit date:2019-06-24
Release date:2021-01-13
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex.
Sci Adv, 8, 2022
6R0T
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BU of 6r0t by Molmil
Getah virus macro domain in complex with ADPr in open conformation
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Non-structural polyprotein, ...
Authors:Ferreira Ramos, A.S, Sulzenbacher, G, Coutard, B.
Deposit date:2019-03-13
Release date:2020-04-01
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography.
Sci Rep, 10, 2020
6R0R
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BU of 6r0r by Molmil
Getah virus macro domain in complex with ADPr covalently bond to Cys34
Descriptor: 1,2-ETHANEDIOL, Non-structural polyprotein, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{S})-2,3,4,5-tetrakis(oxidanyl)pentyl] hydrogen phosphate
Authors:Ferreira Ramos, A.S, Sulzenbacher, G, Coutard, B.
Deposit date:2019-03-13
Release date:2020-04-01
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography.
Sci Rep, 10, 2020
6T3W
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BU of 6t3w by Molmil
Coxsackie B3 2C protein in complex with S-Fluoxetine
Descriptor: (3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, 2C protein, SODIUM ION, ...
Authors:El Kazzi, P, Papageorgiou, N, Ferron, F.P, Bauer, L, van Kuppeveld, F, Coutard, B.
Deposit date:2019-10-11
Release date:2020-11-18
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex.
Sci Adv, 8, 2022
6SX8
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BU of 6sx8 by Molmil
Mopeia Virus Exonuclease domain complexed with Manganese
Descriptor: MANGANESE (II) ION, Nucleoprotein, ZINC ION
Authors:Nguyen, T.H.V, Ferron, F.
Deposit date:2019-09-25
Release date:2021-07-14
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Inhibition of Arenaviridae nucleoprotein exonuclease by bisphosphonate
Iucrj, 2022
6SY8
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BU of 6sy8 by Molmil
Mopeia Virus Exonuclease domain fully depleted of Manganese un ALD compound
Descriptor: Nucleoprotein, ZINC ION
Authors:Nguyen, T.H.V, Ferron, F.
Deposit date:2019-09-27
Release date:2021-07-14
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Inhibition of Arenaviridae nucleoprotein exonuclease by bisphosphonate
Iucrj, 2022
7P27
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BU of 7p27 by Molmil
NMR solution structure of Chikungunya virus macro domain
Descriptor: Polyprotein P1234
Authors:Lykouras, M.V, Tsika, A.C, Papageorgiou, N, Canard, B, Coutard, B, Bentrop, D, Spyroulias, G.A.
Deposit date:2021-07-04
Release date:2022-07-13
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Binding Adaptation of GS-441524 Diversifies Macro Domains and Downregulates SARS-CoV-2 de-MARylation Capacity.
J.Mol.Biol., 434, 2022
2P3L
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BU of 2p3l by Molmil
Crystal Structure of Dengue Methyltransferase in Complex with GpppA and S-Adenosyl-L-Homocysteine
Descriptor: CITRIC ACID, GLYCEROL, GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, ...
Authors:Egloff, M.P, Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-09
Release date:2007-08-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007

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PDB entries from 2024-10-30

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