3QGB
| Crystal structure of FBF-2 R288Y mutant in complex with gld-1 FBEa | Descriptor: | 5'-R(*UP*GP*UP*GP*CP*CP*AP*UP*A)-3', Fem-3 mRNA-binding factor 2 | Authors: | Wang, Y, Qiu, C, Koh, Y.Y, Opperman, L, Gross, L, Hall, T.M.T, Wickens, M. | Deposit date: | 2011-01-24 | Release date: | 2011-03-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Stacking interactions in PUF-RNA complexes. Rna, 17, 2011
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3T9A
| Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with AMPPNP at pH 7.0 | Descriptor: | CADMIUM ION, Inositol Pyrophosphate Kinase, MAGNESIUM ION, ... | Authors: | Wang, H, Falck, J, Hall, T.M.T, Shears, S.B. | Deposit date: | 2011-08-02 | Release date: | 2011-12-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat.Chem.Biol., 8, 2011
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3T99
| Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP and in the absence of cadmium at pH 7.0 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Inositol Pyrophosphate Kinase, MAGNESIUM ION | Authors: | Wang, H, Falck, J, Hall, T.M.T, Shears, S.B. | Deposit date: | 2011-08-02 | Release date: | 2011-12-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat.Chem.Biol., 8, 2011
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3T9B
| Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with AMPPNP at pH 5.2 | Descriptor: | Inositol Pyrophosphate Kinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Wang, H, Falck, J, Hall, T.M.T, Shears, S.B. | Deposit date: | 2011-08-02 | Release date: | 2011-12-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat.Chem.Biol., 8, 2011
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3T7A
| Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP at pH 5.2 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Wang, H, Falck, J, Hall, T.M.T, Shears, S.B. | Deposit date: | 2011-07-29 | Release date: | 2011-12-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat.Chem.Biol., 8, 2011
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3T9F
| Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP and 1,5-(PP)2-IP4 (1,5-IP8) | Descriptor: | (1R,3S,4R,5S,6R)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl bis[trihydrogen (diphosphate)], ADENOSINE-5'-DIPHOSPHATE, CADMIUM ION, ... | Authors: | Wang, H, Falck, J, Hall, T.M.T, Shears, S.B. | Deposit date: | 2011-08-02 | Release date: | 2011-12-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat.Chem.Biol., 8, 2011
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3T54
| Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ATP and Cadmium | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CADMIUM ION, Inositol Pyrophosphate Kinase | Authors: | Wang, H, Falck, J, Hall, T.M.T, Shears, S.B. | Deposit date: | 2011-07-26 | Release date: | 2011-12-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat.Chem.Biol., 8, 2011
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3T9C
| Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with AMPPNP and inositol hexakisphosphate (IP6) | Descriptor: | INOSITOL HEXAKISPHOSPHATE, Inositol Pyrophosphate Kinase, MAGNESIUM ION, ... | Authors: | Wang, H, Falck, J, Hall, T.M.T, Shears, S.B. | Deposit date: | 2011-08-02 | Release date: | 2011-12-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat.Chem.Biol., 8, 2011
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3T9E
| Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP, 5-(PP)-IP5 (5-IP7) and MgF3 (transition state mimic) | Descriptor: | (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, ADENOSINE-5'-DIPHOSPHATE, Inositol Pyrophosphate Kinase, ... | Authors: | Wang, H, Falck, J, Hall, T.M.T, Shears, S.B. | Deposit date: | 2011-08-02 | Release date: | 2011-12-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat.Chem.Biol., 8, 2011
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3T9D
| Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with AMPPNP and 5-(PP)-IP5 (5-IP7) | Descriptor: | (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, Inositol Pyrophosphate Kinase, MAGNESIUM ION, ... | Authors: | Wang, H, Falck, J, Hall, T.M.T, Shears, S.B. | Deposit date: | 2011-08-02 | Release date: | 2011-12-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat.Chem.Biol., 8, 2011
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3QGC
| Crystal structure of FBF-2 R288Y mutant in complex with gld-1 FBEa A7U mutant | Descriptor: | 5'-R(*UP*GP*UP*GP*CP*CP*UP*UP*A)-3', Fem-3 mRNA-binding factor 2 | Authors: | Wang, Y, Qiu, C, Koh, Y.Y, Opperman, L, Gross, L, Hall, T.M.T, Wickens, M. | Deposit date: | 2011-01-24 | Release date: | 2011-03-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Stacking interactions in PUF-RNA complexes. Rna, 17, 2011
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7TU8
| Structure of the L. blandensis dGTPase H125A mutant bound to dGTP and dATP | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | Deposit date: | 2022-02-02 | Release date: | 2022-06-01 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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7TU5
| Structure of the L. blandensis dGTPase in the apo form | Descriptor: | MAGNESIUM ION, dGTP triphosphohydrolase | Authors: | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | Deposit date: | 2022-02-02 | Release date: | 2022-06-01 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.1 Å) | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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7TU6
| Structure of the L. blandensis dGTPase bound to dATP | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, dGTP triphosphohydrolase | Authors: | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | Deposit date: | 2022-02-02 | Release date: | 2022-06-01 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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7TU7
| Structure of the L. blandensis dGTPase H125A mutant bound to dGTP | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, dGTP triphosphohydrolase | Authors: | Klemm, B.P, Sikkema, A.P, Hsu, A.L, Borgnia, M.J, Schaaper, R.M. | Deposit date: | 2022-02-02 | Release date: | 2022-06-01 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP. J.Biol.Chem., 298, 2022
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4DZS
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