3T7A

Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP at pH 5.2

Summary for 3T7A

Entry DOI	10.2210/pdb3t7a/pdb
Related	3T54 3T99 3T9A 3T9B 3T9C 3T9D 3T9E 3T9F
Descriptor	Inositol Pyrophosphate Kinase, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	atp-grasp fold, inositol pyrophosphate kinase, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm, cytosol: O43314
Total number of polymer chains	1
Total formula weight	38556.48
Authors	Wang, H.,Falck, J.,Hall, T.M.T.,Shears, S.B. (deposition date: 2011-07-29, release date: 2011-12-07, Last modification date: 2023-09-13)
Primary citation	Wang, H.,Falck, J.R.,Hall, T.M.,Shears, S.B. Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat.Chem.Biol., 8:111-116, 2011 Cited by PubMed: 22119861 DOI: 10.1038/nchembio.733 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation