3T7A
Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP at pH 5.2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Inositol Pyrophosphate Kinase | polymer | 330 | 37568.9 | 1 | UniProt (O43314) Pfam (PF18086) | Homo sapiens (human) | |
| 2 | B (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 3 | C, D, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | F, H, L (A) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 5 | G, I, J, K, M (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 6 | N (A) | water | water | 18.0 | 431 | Chemie (HOH) |
Sequence modifications
A: 41 - 366 (UniProt: O43314)
| PDB | External Database | Details |
|---|---|---|
| Gly 37 | - | expression tag |
| Ser 38 | - | expression tag |
| Phe 39 | - | expression tag |
| Thr 40 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37568.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 987.6 | |
| All* | Total formula weight | 38556.5 |
