3T9F
Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with ADP and 1,5-(PP)2-IP4 (1,5-IP8)
Summary for 3T9F
Entry DOI | 10.2210/pdb3t9f/pdb |
Related | 3T54 3T7A 3T99 3T9A 3T9B 3T9C 3T9D 3T9E |
Descriptor | Inositol Pyrophosphate Kinase, ADENOSINE-5'-DIPHOSPHATE, (1R,3S,4R,5S,6R)-2,4,5,6-tetrakis(phosphonooxy)cyclohexane-1,3-diyl bis[trihydrogen (diphosphate)], ... (6 entities in total) |
Functional Keywords | atp-grasp fold, inositol pyrophosphate kinase, phosphoryl transferase, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytosol: O43314 |
Total number of polymer chains | 1 |
Total formula weight | 39050.02 |
Authors | Wang, H.,Falck, J.,Hall, T.M.T.,Shears, S.B. (deposition date: 2011-08-02, release date: 2011-12-07, Last modification date: 2024-02-28) |
Primary citation | Wang, H.,Falck, J.R.,Hall, T.M.,Shears, S.B. Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat.Chem.Biol., 8:111-116, 2011 Cited by PubMed: 22119861DOI: 10.1038/nchembio.733 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report