1AA9
| HUMAN C-HA-RAS(1-171)(DOT)GDP, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | C-HA-RAS, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Ito, Y, Yamasaki, Y, Muto, Y, Kawai, G, Nishimura, S, Miyazawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 1997-01-27 | Release date: | 1997-07-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Regional polysterism in the GTP-bound form of the human c-Ha-Ras protein. Biochemistry, 36, 1997
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6JLY
| eIF2a - eIF2B complex | Descriptor: | Eukaryotic translation initiation factor 2 subunit alpha, PHOSPHATE ION, Probable translation initiation factor eIF-2B subunit beta, ... | Authors: | Kashiwagi, K, Ito, T. | Deposit date: | 2019-03-07 | Release date: | 2019-05-01 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural basis for eIF2B inhibition in integrated stress response. Science, 364, 2019
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1GCK
| THERMUS THERMOPHILUS ASPARTATE AMINOTRANSFERASE DOUBLE MUTANT 1 COMPLEXED WITH ASPARTATE | Descriptor: | ASPARTATE AMINOTRANSFERASE, ASPARTIC ACID, PYRIDOXAL-5'-PHOSPHATE | Authors: | Ura, H, Nakai, T, Hirotsu, K, Kuramitsu, S. | Deposit date: | 2000-08-04 | Release date: | 2001-11-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Substrate recognition mechanism of thermophilic dual-substrate enzyme. J.Biochem., 130, 2001
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5HI8
| Structure of T-type Phycobiliprotein Lyase CpeT from Prochlorococcus phage P-HM1 | Descriptor: | ACETATE ION, Antenna protein, MAGNESIUM ION | Authors: | Gasper, R, Schwach, J, Frankenberg-Dinkel, N, Hofmann, E. | Deposit date: | 2016-01-11 | Release date: | 2017-01-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Distinct Features of Cyanophage-encoded T-type Phycobiliprotein Lyase Phi CpeT: THE ROLE OF AUXILIARY METABOLIC GENES. J. Biol. Chem., 292, 2017
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6KEM
| Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in apo-form 2 | Descriptor: | Glutathione S-transferase E14 | Authors: | Koiwai, K, Inaba, K, Morohashi, K, Yumoto, F, Niwa, R, Senda, T. | Deposit date: | 2019-07-04 | Release date: | 2019-10-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo. J.Biol.Chem., 295, 2020
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1GC4
| THERMUS THERMOPHILUS ASPARTATE AMINOTRANSFERASE TETRA MUTANT 2 COMPLEXED WITH ASPARTATE | Descriptor: | ASPARTATE AMINOTRANSFERASE, ASPARTIC ACID, PYRIDOXAL-5'-PHOSPHATE | Authors: | Ura, H, Nakai, T, Hirotsu, K, Kuramitsu, S. | Deposit date: | 2000-07-19 | Release date: | 2001-09-05 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Substrate recognition mechanism of thermophilic dual-substrate enzyme. J.Biochem., 130, 2001
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6IP6
| Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | Deposit date: | 2018-11-02 | Release date: | 2019-05-29 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | HCV IRES Captures an Actively Translating 80S Ribosome. Mol.Cell, 74, 2019
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6KEL
| Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in apo-form | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glutathione S-transferase E14 | Authors: | Koiwai, K, Inaba, K, Morohashi, K, Yumoto, F, Senda, T, Niwa, R. | Deposit date: | 2019-07-04 | Release date: | 2019-10-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo. J.Biol.Chem., 295, 2020
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6KEQ
| Crystal structure of D113A mutant of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in apo-form | Descriptor: | Glutathione S-transferase E14 | Authors: | Koiwai, K, Inaba, K, Morohashi, K, Yumoto, F, Niwa, R, Senda, T. | Deposit date: | 2019-07-04 | Release date: | 2019-10-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo. J.Biol.Chem., 295, 2020
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6K72
| eIF2(aP) - eIF2B complex | Descriptor: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ... | Authors: | Kashiwagi, K, Yokoyama, T, Ito, T. | Deposit date: | 2019-06-05 | Release date: | 2019-07-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural basis for eIF2B inhibition in integrated stress response. Science, 364, 2019
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6KEN
| Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in glutathione-bound form | Descriptor: | GLUTATHIONE, Glutathione S-transferase E14 | Authors: | Koiwai, K, Inaba, K, Morohashi, K, Yumoto, F, Niwa, R, Senda, T. | Deposit date: | 2019-07-04 | Release date: | 2019-10-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo. J.Biol.Chem., 295, 2020
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6KER
| Crystal structure of D113A mutant of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in glutathione-bound form | Descriptor: | GLUTATHIONE, Glutathione S-transferase E14 | Authors: | Koiwai, K, Inaba, K, Morohashi, K, Yumoto, F, Niwa, R, Senda, T. | Deposit date: | 2019-07-04 | Release date: | 2019-10-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo. J.Biol.Chem., 295, 2020
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6K71
| eIF2 - eIF2B complex | Descriptor: | Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ... | Authors: | Kashiwagi, K, Yokoyama, T, Ito, T. | Deposit date: | 2019-06-05 | Release date: | 2019-07-10 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis for eIF2B inhibition in integrated stress response. Science, 364, 2019
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5AXM
| Crystal structure of Thg1 like protein (TLP) with tRNA(Phe) | Descriptor: | MAGNESIUM ION, RNA (75-MER), tRNA(His)-5'-guanylyltransferase (Thg1) like protein | Authors: | Kimura, S, Suzuki, T, Yu, J, Kato, K, Yao, M. | Deposit date: | 2015-07-31 | Release date: | 2016-08-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Template-dependent nucleotide addition in the reverse (3'-5') direction by Thg1-like protein Sci Adv, 2, 2016
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5AXN
| Crystal structure of Thg1 like protein (TLP) with tRNA(Phe) and GDPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RNA (75-MER), ... | Authors: | Kimura, S, Suzuki, T, Yu, J, Kato, K, Yao, M. | Deposit date: | 2015-07-31 | Release date: | 2016-08-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.703 Å) | Cite: | Template-dependent nucleotide addition in the reverse (3'-5') direction by Thg1-like protein Sci Adv, 2, 2016
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3CTH
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5D1J
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5AXK
| Crystal structure of Thg1 like protein (TLP) | Descriptor: | GLYCEROL, tRNA(His)-5'-guanylyltransferase (Thg1) like protein | Authors: | Kimura, S, Suzuki, T, Yu, J, Kato, K, Yao, M. | Deposit date: | 2015-07-31 | Release date: | 2016-08-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Template-dependent nucleotide addition in the reverse (3'-5') direction by Thg1-like protein Sci Adv, 2, 2016
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5AXL
| Crystal structure of Thg1 like protein (TLP) with GTP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, tRNA(His)-5'-guanylyltransferase (Thg1) like protein | Authors: | Kimura, S, Suzuki, T, Yu, J, Kato, K, Yao, M. | Deposit date: | 2015-07-31 | Release date: | 2016-08-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.998 Å) | Cite: | Template-dependent nucleotide addition in the reverse (3'-5') direction by Thg1-like protein Sci Adv, 2, 2016
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5DST
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3CTJ
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5ANR
| Structure of a human 4E-T - DDX6 - CNOT1 complex | Descriptor: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER, PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 | Authors: | Basquin, J, Oezguer, S, Conti, E. | Deposit date: | 2015-09-08 | Release date: | 2015-10-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | Structure of a Human 4E-T/Ddx6/Cnot1 Complex Reveals the Different Interplay of Ddx6-Binding Proteins with the Ccr4-not Complex. Cell Rep., 13, 2015
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6RNA
| RIP2 Kinase Catalytic Domain complex with 2({4[(1,3benzothiazol5yl)amino]6(2methylpropane2sulfonyl)quinazolin7yl}oxy)ethan1ol | Descriptor: | 2-[4-(1,3-benzothiazol-5-ylamino)-6-~{tert}-butylsulfonyl-quinazolin-7-yl]oxyethanol, Receptor-interacting serine/threonine-protein kinase 2 | Authors: | Convery, M.A, Haile, P.A. | Deposit date: | 2019-05-08 | Release date: | 2019-07-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2-((4-(Benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases. J.Med.Chem., 62, 2019
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4NA2
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4NA1
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