7B0U
 
 | | Stressosome complex from Listeria innocua | | Descriptor: | RsbR protein, RsbS protein | | Authors: | Miksys, A, Fu, L, Madej, M.G, Ziegler, C. | | Deposit date: | 2020-11-22 | | Release date: | 2021-12-01 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.86 Å) | | Cite: | Molecular insights into intra-complex signal transmission during stressosome activation.
Commun Biol, 5, 2022
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4TLT
 | | Crystal structure of human transthyretin | | Descriptor: | MAGNESIUM ION, Transthyretin | | Authors: | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | | Deposit date: | 2014-05-30 | | Release date: | 2015-10-21 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
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4TM9
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4TLK
 | | Crystal Structure of Human Transthyretin Ser85Pro/Glu92Pro Mutant | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, SODIUM ION, ... | | Authors: | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | | Deposit date: | 2014-05-30 | | Release date: | 2015-10-21 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.44 Å) | | Cite: | Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
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7ZRY
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1S3Q
 | | Crystal structures of a novel open pore ferritin from the hyperthermophilic Archaeon Archaeoglobus fulgidus | | Descriptor: | ZINC ION, ferritin | | Authors: | Johnson, E, Cascio, D, Sawaya, M, Schroeder, I. | | Deposit date: | 2004-01-13 | | Release date: | 2005-04-12 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structures of a tetrahedral open pore ferritin from the hyperthermophilic archaeon Archaeoglobus fulgidus.
Structure, 13, 2005
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2COJ
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2COG
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2COI
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6WLA
 | | Antigen binding fragment of ch128.1 | | Descriptor: | Fab ch128.1 heavy chain, Fab ch128.1 light chain, GLYCEROL | | Authors: | Helguera, G, Rodriguez, J.A, Sawaya, M, Cascio, D, Zink, S, Ziegenbein, J, Short, C. | | Deposit date: | 2020-04-18 | | Release date: | 2021-03-24 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Host receptor-targeted therapeutic approach to counter pathogenic New World mammarenavirus infections.
Nat Commun, 13, 2022
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2HGX
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3UFL
 | | Discovery of Pyrrolidine-based b-Secretase Inhibitors: Lead Advancement through Conformational Design for Maintenance of Ligand Binding Efficiency | | Descriptor: | (1R,4'S)-3,4-dihydro-2H-spiro[naphthalene-1,3'-pyrrolidin]-4'-yl[(2S,4R)-2,4-diphenylpiperidin-1-yl]methanone, Beta-secretase 1, GLYCEROL, ... | | Authors: | Allison, T, Munshi, S, Soisson, S.M. | | Deposit date: | 2011-11-01 | | Release date: | 2012-01-18 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Discovery of pyrrolidine-based beta-secretase inhibitors: Lead advancement through conformational design for maintenance of ligand binding efficiency.
Bioorg.Med.Chem.Lett., 22, 2012
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2HDK
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2HHF
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2HGW
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2HG8
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3H0B
 | | Discovery of aminoheterocycles as a novel beta-secretase inhibitor class | | Descriptor: | 4-[(1S)-1-(3-fluoro-4-methoxyphenyl)-2-(2-methoxy-5-nitrophenyl)ethyl]-1H-imidazol-2-amine, Beta-secretase 1 | | Authors: | Allison, T.J. | | Deposit date: | 2009-04-08 | | Release date: | 2009-07-07 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Discovery of aminoheterocycles as a novel beta-secretase inhibitor class: pH dependence on binding activity part 1.
Bioorg.Med.Chem.Lett., 19, 2009
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1WC9
 | | The crystal structure of truncated mouse bet3p | | Descriptor: | GLYCEROL, MYRISTIC ACID, TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT3 | | Authors: | Kim, Y.-G, Lee, H.-S, Sacher, M, Oh, B.-H. | | Deposit date: | 2004-11-10 | | Release date: | 2004-12-13 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal Structure of Bet3 Reveals a Novel Mechanism for Golgi Localization of Tethering Factor Trapp
Nat.Struct.Mol.Biol., 12, 2005
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1WC8
 | | The crystal structure of mouse bet3p | | Descriptor: | MYRISTIC ACID, TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT3 | | Authors: | Kim, Y.-G, Sacher, M, Oh, B.-H. | | Deposit date: | 2004-11-10 | | Release date: | 2004-12-13 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal Structure of Bet3 Reveals a Novel Mechanism for Golgi Localization of Tethering Factor Trapp
Nat.Struct.Mol.Biol., 12, 2005
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