7M18
| HeLa-tubulin in complex with cryptophycin 1 | Descriptor: | Cryptophycin 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Eren, E. | Deposit date: | 2021-03-12 | Release date: | 2021-09-08 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action. J.Biol.Chem., 297, 2021
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7M20
| 18-mer HeLa-tubulin rings in complex with Cryptophycin 1 | Descriptor: | Cryptophycin 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Eren, E. | Deposit date: | 2021-03-15 | Release date: | 2021-09-08 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.84 Å) | Cite: | Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action. J.Biol.Chem., 297, 2021
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7LXB
| HeLa-tubulin in complex with cryptophycin 52 | Descriptor: | Cryptophycin 52, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Eren, E. | Deposit date: | 2021-03-03 | Release date: | 2021-09-08 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action. J.Biol.Chem., 297, 2021
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3SZD
| Crystal structure of Pseudomonas aeruginosa OccK2 (OpdF) | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, SULFATE ION, ... | Authors: | van den Berg, B, Eren, E. | Deposit date: | 2011-07-18 | Release date: | 2012-02-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.311 Å) | Cite: | Substrate Specificity within a Family of Outer Membrane Carboxylate Channels. Plos Biol., 10, 2012
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3SYB
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3T24
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5NNZ
| Crystal structure of human ODA16 | Descriptor: | Dynein assembly factor with WDR repeat domains 1 | Authors: | Lorentzen, E, Taschner, T, Basquin, J. | Deposit date: | 2017-04-10 | Release date: | 2017-06-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.651 Å) | Cite: | Purification and crystal structure of human ODA16: Implications for ciliary import of outer dynein arms by the intraflagellar transport machinery. Protein Sci., 29, 2020
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5MZH
| Crystal structure of ODA16 from Chlamydomonas reinhardtii | Descriptor: | Dynein assembly factor with WDR repeat domains 1, SULFATE ION | Authors: | Lorentzen, E, Taschner, M, Basquin, J, Mourao, A. | Deposit date: | 2017-01-31 | Release date: | 2017-03-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.398 Å) | Cite: | Structural basis of outer dynein arm intraflagellar transport by the transport adaptor protein ODA16 and the intraflagellar transport protein IFT46. J. Biol. Chem., 292, 2017
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6CF2
| Crystal structure of HIV-1 Rev (residues 1-93)-RNA aptamer complex | Descriptor: | Anti-Rev Antibody, heavy chain, light chain, ... | Authors: | Eren, E, Dearborn, A.D, Wingfield, P.T. | Deposit date: | 2018-02-13 | Release date: | 2018-07-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of an RNA Aptamer that Can Inhibit HIV-1 by Blocking Rev-Cognate RNA (RRE) Binding and Rev-Rev Association. Structure, 26, 2018
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4YIL
| OYE1 W116A COMPLEXED WITH (Z)-METHYL 3-CYANO-3-(4-FLUOROPHENYL)ACRYLATE IN A NON PRODUCTIVE BINDING MODE | Descriptor: | FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, NADPH dehydrogenase 1, ... | Authors: | Santangelo, S, Brenna, E, Stewart, J.D, Powell III, R.W. | Deposit date: | 2015-03-02 | Release date: | 2016-01-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.461 Å) | Cite: | Opposite Enantioselectivity in the Bioreduction of (Z)-beta-Aryl-beta-cyanoacrylates Mediated by the Tryptophan 116 Mutants of Old Yellow Enzyme 1: Synthetic Approach to (R)- and (S)-beta-Aryl-gamma-lactams Adv.Synth.Catal., 357, 2015
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4YNC
| OYE1 W116A COMPLEXED WITH (Z)-METHYL-3-CYANO-3-PHENYLACRYLATE IN A NON PRODUCTIVE BINDING MODE | Descriptor: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, NADPH dehydrogenase 1, ... | Authors: | Santangelo, S, Brenna, E, Stewart, J.D, Powell III, R.W. | Deposit date: | 2015-03-09 | Release date: | 2016-01-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.498 Å) | Cite: | Opposite Enantioselectivity in the Bioreduction of (Z)-beta-Aryl-beta-cyanoacrylates Mediated by the Tryptophan 116 Mutants of Old Yellow Enzyme 1: Synthetic Approach to (R)- and (S)-beta-Aryl-gamma-lactams Adv.Synth.Catal., 357, 2015
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6F6P
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4FMS
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3SY9
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3T0S
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3T20
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3SY7
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3SYS
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4V0O
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6YYE
| TREM2 extracellular domain (19-131) in complex with single-chain variable fragment (scFv-2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, TREM2 Single chain variable 2, Triggering receptor expressed on myeloid cells 2 | Authors: | Szykowska, A, Preger, C, Krojer, T, Mukhopadhyay, S.M.M, McKinley, G, Graslund, S, Wigren, E, Persson, H, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Di Daniel, E, Burgess-Brown, N, Bullock, A. | Deposit date: | 2020-05-04 | Release date: | 2021-02-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.36 Å) | Cite: | Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain. Structure, 29, 2021
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5I6Y
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4NKL
| Crystal structure of Staphylococcal nuclease variant Delta+PHS V66A/I92Q at cryogenic temperature | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | Authors: | Caro, J.A, Sorenson, J.L, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. | Deposit date: | 2013-11-12 | Release date: | 2013-11-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Pressure effects in proteins To be Published
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4NMZ
| Crystal structure of Staphylococcal nuclease variant Delta+PHS V23Q/V66A at cryogenic temperature | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | Authors: | Caro, J.A, Sorenson, J.L, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. | Deposit date: | 2013-11-15 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Cavities in proteins To be Published
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3SR1
| Crystal structure of Staphylococcal nuclease variant Delta+PHS A69G bound to Ca2+ and thymidine-5',3'-diphosphate at cryogenic temperature | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, thermonuclease | Authors: | Doctrow, B.M, Schlessman, J.L, Garcia-Moreno E, B, Heroux, A. | Deposit date: | 2011-07-06 | Release date: | 2011-07-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure of Staphylococcal nuclease variant Delta+PHS A69G bound to Ca2+ and thymidine-5',3'-diphosphate at cryogenic temperature To be Published
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3T13
| Crystal structure of Staphylococcal nuclease variant Delta+PHS A69G at cryogenic temperature | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, CALCIUM ION, PHOSPHATE ION, ... | Authors: | Doctrow, B.M, Schlessman, J.L, Garcia-Moreno E, B, Heroux, A. | Deposit date: | 2011-07-21 | Release date: | 2011-08-03 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of Staphylococcal nuclease variant Delta+PHS A69G at cryogenic temperature To be Published
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