4YNC

OYE1 W116A COMPLEXED WITH (Z)-METHYL-3-CYANO-3-PHENYLACRYLATE IN A NON PRODUCTIVE BINDING MODE

Summary for 4YNC

Entry DOI	10.2210/pdb4ync/pdb
Related	4GBU
Descriptor	NADPH dehydrogenase 1, FLAVIN MONONUCLEOTIDE, methyl (2Z)-3-cyano-3-phenylprop-2-enoate, ... (5 entities in total)
Functional Keywords	oxidoreductase, catalytic activity, fmn binding, old yellow enzyme
Biological source	Saccharomyces pastorianus (Lager yeast)
Total number of polymer chains	1
Total formula weight	45245.94
Authors	Santangelo, S.,Brenna, E.,Stewart, J.D.,Powell III, R.W. (deposition date: 2015-03-09, release date: 2016-01-20, Last modification date: 2024-01-10)
Primary citation	Brenna, E.,Crotti, M.,Gatti, F.G.,Monti, D.,Parmeggiani, F.,Powell III, R.W.,Santangelo, S.,Stewart, J.D. Opposite Enantioselectivity in the Bioreduction of (Z)-beta-Aryl-beta-cyanoacrylates Mediated by the Tryptophan 116 Mutants of Old Yellow Enzyme 1: Synthetic Approach to (R)- and (S)-beta-Aryl-gamma-lactams Adv.Synth.Catal., 357:1849-1860., 2015 Cited by DOI: 10.1002/adsc.201500206 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.498 Å)

Structure validation