4YNC
OYE1 W116A COMPLEXED WITH (Z)-METHYL-3-CYANO-3-PHENYLACRYLATE IN A NON PRODUCTIVE BINDING MODE
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue FMN A 401 |
| Chain | Residue |
| A | PRO34 |
| A | GLY324 |
| A | ASN325 |
| A | GLY347 |
| A | ARG348 |
| A | 4EG402 |
| A | HOH597 |
| A | HOH599 |
| A | HOH697 |
| A | HOH831 |
| A | PRO35 |
| A | LEU36 |
| A | THR37 |
| A | GLY72 |
| A | GLN114 |
| A | HIS191 |
| A | ASN194 |
| A | ARG243 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue 4EG A 402 |
| Chain | Residue |
| A | THR37 |
| A | GLY72 |
| A | PHE74 |
| A | TYR82 |
| A | ALA116 |
| A | ASN194 |
| A | TYR196 |
| A | TYR375 |
| A | FMN401 |
| A | HOH562 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 403 |
| Chain | Residue |
| A | HOH993 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"9830020","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11668181","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7881908","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9830019","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11668181","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7881908","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 319 |
| Chain | Residue | Details |
| A | THR37 | electrostatic stabiliser, hydrogen bond donor |
| A | HIS191 | electrostatic stabiliser, hydrogen bond donor |
| A | ASN194 | electrostatic stabiliser, hydrogen bond donor |
| A | TYR196 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ASN251 | hydrogen bond donor, increase acidity |
