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5U3O
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BU of 5u3o by Molmil
Crystal Structure of DH511.2_K3 Fab in Complex with HIV-1 gp41 MPER Peptide
Descriptor: DH511.2_K3 Fab Heavy Chain, DH511.2_K3 Fab Light Chain, gp41 MPER peptide
Authors:Ofek, G, Wu, L, Lougheed, C.S, Williams, L.D, Nicely, N.I, Haynes, B.F.
Deposit date:2016-12-02
Release date:2017-02-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.761 Å)
Cite:Potent and broad HIV-neutralizing antibodies in memory B cells and plasma.
Sci Immunol, 2, 2017
5U3P
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BU of 5u3p by Molmil
Crystal Structure of DH511.4 Fab
Descriptor: DH511.4 Fab Heavy Chain, DH511.4 Fab Light Chain
Authors:Nicely, N.I, Williams, L.D, Ofek, G, Haynes, B.F.
Deposit date:2016-12-02
Release date:2017-02-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Potent and broad HIV-neutralizing antibodies in memory B cells and plasma.
Sci Immunol, 2, 2017
5U3J
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BU of 5u3j by Molmil
Crystal Structure of DH511.1 Fab in Complex with HIV-1 gp41 MPER Peptide
Descriptor: DH511.1 Heavy Chain, DH511.1 Light Chain, gp41 MPER peptide
Authors:Ofek, G, Wu, L, Lougheed, C.S, Williams, L.D, Nicely, N.I, Haynes, B.F.
Deposit date:2016-12-02
Release date:2017-02-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Potent and broad HIV-neutralizing antibodies in memory B cells and plasma.
Sci Immunol, 2, 2017
5TKJ
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BU of 5tkj by Molmil
Structure of vaccine-elicited diverse HIV-1 neutralizing antibody vFP1.01 in complex with HIV-1 fusion peptide residue 512-519
Descriptor: HIV-1 fusion peptide residue 512-519, SULFATE ION, vFP1.01 chimeric mouse antibody heavy chain, ...
Authors:Xu, K, Liu, K, Kwong, P.D.
Deposit date:2016-10-06
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.118 Å)
Cite:Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Nat. Med., 24, 2018
5TKK
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BU of 5tkk by Molmil
Structure of mouse vaccination-elicited HIV neutralizing antibody vFP5.01 in complex with HIV-1 fusion peptide residue 512-519
Descriptor: HIV-1 fusion peptide residue 512-519, mouse antibody vFP5.01 heavy chain, mouse antibody vFP5.01 light chain
Authors:Xu, K, Liu, K, Kwong, P.D.
Deposit date:2016-10-06
Release date:2018-04-04
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Nat. Med., 24, 2018
4JPW
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BU of 4jpw by Molmil
Crystal structure of broadly and potently neutralizing antibody 12a21 in complex with hiv-1 strain 93th057 gp120 mutant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEAVY CHAIN OF ANTIBODY 12A21, ...
Authors:Acharya, P, Luongo, T, Zhou, T, Kwong, P.D.
Deposit date:2013-03-19
Release date:2013-04-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.904 Å)
Cite:Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization.
Cell(Cambridge,Mass.), 153, 2013
5U0U
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BU of 5u0u by Molmil
Crystal Structure of DH270.1 (unliganded, single-chain Fv) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
Descriptor: DH270.1 single-chain variable fragment
Authors:Fera, D, Harrison, S.C.
Deposit date:2016-11-27
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.428 Å)
Cite:Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
5TQA
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BU of 5tqa by Molmil
Crystal Structure of DH270.6 (unliganded) from the DH270 Broadly Neutralizing N332-Glycan Dependent Lineage
Descriptor: DH270.6 Fab heavy chain, DH270.6 Fab light chain
Authors:Fera, D, Harrison, S.C.
Deposit date:2016-10-23
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.723 Å)
Cite:Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
5TRP
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BU of 5trp by Molmil
Crystal Structure of the Unliganded DH270 Cooperating Lineage Member DH272
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH272 Fab heavy chain, DH272 Fab light chain, ...
Authors:Fera, D, Harrison, S.C.
Deposit date:2016-10-27
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.692 Å)
Cite:Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
5TPL
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BU of 5tpl by Molmil
Crystal Structure of DH270.3 (unliganded) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
Descriptor: DH270.3 Fab heavy chain, DH270.3 Fab light chain
Authors:Fera, D, Harrison, S.C.
Deposit date:2016-10-20
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
5U0R
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BU of 5u0r by Molmil
Crystal Structure of DH270.UCA1 (unliganded) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
Descriptor: DH270.UCA1 heavy chain, DH270.UCA1 light chain, SULFATE ION
Authors:Fera, D, Harrison, S.C.
Deposit date:2016-11-26
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.295 Å)
Cite:Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
6BF4
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BU of 6bf4 by Molmil
Crystal Structure of HIV-1 Clade AE Strain CNE55 gp120 Core in Complex with Neutralizing Antibody VRC-PG05 that Targets the Center of the Silent Face on the Outer Domain of gp120
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhou, T, Kwong, P.D.
Deposit date:2017-10-25
Release date:2018-03-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.382 Å)
Cite:A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope.
Immunity, 48, 2018
3SE8
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BU of 3se8 by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC03 in complex with HIV-1 gp120
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kwong, P.D, Zhou, T.
Deposit date:2011-06-10
Release date:2011-08-10
Last modified:2021-04-07
Method:X-RAY DIFFRACTION (1.895 Å)
Cite:Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing.
Science, 333, 2011
5TPP
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BU of 5tpp by Molmil
Crystal Structure of DH270.5 (unliganded) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
Descriptor: CITRIC ACID, DH270.5 Fab heavy chain, DH270.5 Fab light chain, ...
Authors:Fera, D, Harrison, S.C.
Deposit date:2016-10-20
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
5U15
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BU of 5u15 by Molmil
Crystal Structure of DH270.UCA3 (unliganded) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
Descriptor: DH270.UCA3 heavy chain, DH270.UCA3 light chain
Authors:Fera, D, Harrison, S.C.
Deposit date:2016-11-27
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
7MFB
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BU of 7mfb by Molmil
Crystal structure of antibody 10E8v4 Fab - light chain H31F variant
Descriptor: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
Authors:Kwon, Y.D, Kwong, P.D.
Deposit date:2021-04-08
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7MFA
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BU of 7mfa by Molmil
Crystal structure of antibody 10E8v4-P100fA+P100gA Fab
Descriptor: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
Authors:Kwon, Y.D, Kwong, P.D.
Deposit date:2021-04-08
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7MF8
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BU of 7mf8 by Molmil
Crystal structure of antibody 10E8v4-P100fA Fab in space group P6422
Descriptor: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
Authors:Kwon, Y.D, Kwong, P.D.
Deposit date:2021-04-08
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7MF7
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BU of 7mf7 by Molmil
Crystal structure of antibody 10E8v4-P100gA Fab
Descriptor: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
Authors:Kwon, Y.D, Kwong, P.D.
Deposit date:2021-04-08
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
7MF9
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BU of 7mf9 by Molmil
Crystal structure of antibody 10E8v4-P100fA Fab in space group C2
Descriptor: Antibody 10E8v4 Fab heavy chain, Antibody 10E8v4 Fab light chain
Authors:Kwon, Y.D, Kwong, P.D.
Deposit date:2021-04-08
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.
Antibodies, 10, 2021
6DE7
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BU of 6de7 by Molmil
Crystal Structure at 4.3 A Resolution of Glycosylated HIV-1 Clade A BG505 SOSIP.664 Prefusion Env Trimer with Interdomain Stabilization 113C-429GCG in Complex with Broadly Neutralizing Antibodies PGT122 and 35O22
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 heavy chain, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2018-05-11
Release date:2018-06-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.123 Å)
Cite:Interdomain Stabilization Impairs CD4 Binding and Improves Immunogenicity of the HIV-1 Envelope Trimer.
Cell Host Microbe, 23, 2018
3SE9
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BU of 3se9 by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC-PG04 in complex with HIV-1 gp120
Descriptor: (R,R)-2,3-BUTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kwong, P.D, Zhou, T.
Deposit date:2011-06-10
Release date:2011-08-10
Last modified:2021-04-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing.
Science, 333, 2011
5V7J
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BU of 5v7j by Molmil
Crystal Structure at 3.7 A Resolution of Glycosylated HIV-1 Clade A BG505 SOSIP.664 Prefusion Env Trimer with Four Glycans (N197, N276, N362, and N462) removed in Complex with Neutralizing Antibodies 3H+109L and 35O22.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 35O22 Fab heavy chain, ...
Authors:Stewart-Jones, G.B.E, Zhou, T, Kwong, P.D.
Deposit date:2017-03-20
Release date:2017-06-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.907 Å)
Cite:Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation.
Cell Rep, 19, 2017
5JR1
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BU of 5jr1 by Molmil
Crystal structure of 10E8 gHV-matureL antigen-binding fragment.
Descriptor: 10E8 heavy chain, 10E8 mature light chain, ZINC ION
Authors:Joyce, M.G, Mascola, J.R, Kwong, P.D.
Deposit date:2016-05-05
Release date:2016-07-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8.
Plos One, 11, 2016
5JO5
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BU of 5jo5 by Molmil
Crystal structure of 10E8 gHV-gLV antigen-binding fragment.
Descriptor: 10E8 gHV, 10E8 gLV
Authors:Joyce, M.G, Mascola, J.R, Kwong, P.D.
Deposit date:2016-05-02
Release date:2016-07-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8.
Plos One, 11, 2016

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