3LNM
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![BU of 3lnm by Molmil](/molmil-images/mine/3lnm) | F233W mutant of the Kv2.1 paddle-Kv1.2 chimera channel | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, F233W mutant of the Kv2.1 paddle-Kv1.2 chimera, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Tao, X, Lee, A, Limapichat, W, Dougherty, D.A, MacKinnon, R. | Deposit date: | 2010-02-02 | Release date: | 2010-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A gating charge transfer center in voltage sensors. Science, 328, 2010
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3MT5
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![BU of 3mt5 by Molmil](/molmil-images/mine/3mt5) | Crystal Structure of the Human BK Gating Apparatus | Descriptor: | CALCIUM ION, Potassium large conductance calcium-activated channel, subfamily M, ... | Authors: | Yuan, P, MacKinnon, R. | Deposit date: | 2010-04-30 | Release date: | 2010-06-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolution. Science, 329, 2010
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6C3P
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![BU of 6c3p by Molmil](/molmil-images/mine/6c3p) | Cryo-EM structure of human KATP bound to ATP and ADP in propeller form | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | Authors: | Lee, K.P.K, Chen, J, MacKinnon, R. | Deposit date: | 2018-01-10 | Release date: | 2018-01-24 | Method: | ELECTRON MICROSCOPY (5.6 Å) | Cite: | Molecular structure of human KATP in complex with ATP and ADP. Elife, 6, 2017
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6C3O
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![BU of 6c3o by Molmil](/molmil-images/mine/6c3o) | Cryo-EM structure of human KATP bound to ATP and ADP in quatrefoil form | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | Authors: | Lee, K.P.K, Chen, J, MacKinnon, R. | Deposit date: | 2018-01-10 | Release date: | 2018-01-31 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Molecular structure of human KATP in complex with ATP and ADP Elife, 6, 2017
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6CNN
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![BU of 6cnn by Molmil](/molmil-images/mine/6cnn) | |
6B3R
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![BU of 6b3r by Molmil](/molmil-images/mine/6b3r) | Structure of the mechanosensitive channel Piezo1 | Descriptor: | Piezo-type mechanosensitive ion channel component 1, unknown fragment | Authors: | Guo, Y.R, MacKinnon, R. | Deposit date: | 2017-09-22 | Release date: | 2017-12-20 | Last modified: | 2018-05-16 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure-based membrane dome mechanism for Piezo mechanosensitivity. Elife, 6, 2017
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6COY
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![BU of 6coy by Molmil](/molmil-images/mine/6coy) | |
6CNO
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![BU of 6cno by Molmil](/molmil-images/mine/6cno) | |
6PBY
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![BU of 6pby by Molmil](/molmil-images/mine/6pby) | |
6PBX
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![BU of 6pbx by Molmil](/molmil-images/mine/6pbx) | |
1ID1
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![BU of 1id1 by Molmil](/molmil-images/mine/1id1) | CRYSTAL STRUCTURE OF THE RCK DOMAIN FROM E.COLI POTASSIUM CHANNEL | Descriptor: | PUTATIVE POTASSIUM CHANNEL PROTEIN | Authors: | Jiang, Y, Pico, A, Cadene, M, Chait, B.T, MacKinnon, R. | Deposit date: | 2001-04-02 | Release date: | 2001-04-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the RCK domain from the E. coli K+ channel and demonstration of its presence in the human BK channel. Neuron, 29, 2001
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1J95
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![BU of 1j95 by Molmil](/molmil-images/mine/1j95) | |
1JVM
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![BU of 1jvm by Molmil](/molmil-images/mine/1jvm) | |
1BE9
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![BU of 1be9 by Molmil](/molmil-images/mine/1be9) | THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM CRIPT. | Descriptor: | CRIPT, PSD-95 | Authors: | Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R. | Deposit date: | 1998-05-20 | Release date: | 1998-10-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ. Cell(Cambridge,Mass.), 85, 1996
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1BL8
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![BU of 1bl8 by Molmil](/molmil-images/mine/1bl8) | POTASSIUM CHANNEL (KCSA) FROM STREPTOMYCES LIVIDANS | Descriptor: | POTASSIUM ION, PROTEIN (POTASSIUM CHANNEL PROTEIN) | Authors: | Doyle, D.A, Cabral, J.M, Pfuetzner, R.A, Kuo, A, Gulbis, J.M, Cohen, S.L, Chait, B.T, Mackinnon, R. | Deposit date: | 1998-07-23 | Release date: | 1998-07-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science, 280, 1998
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1BYW
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![BU of 1byw by Molmil](/molmil-images/mine/1byw) | |
7S5Y
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![BU of 7s5y by Molmil](/molmil-images/mine/7s5y) | Human KATP channel in open conformation, focused on Kir and one SUR, position 2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | Authors: | Zhao, C, MacKinnon, R. | Deposit date: | 2021-09-12 | Release date: | 2021-12-01 | Last modified: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Molecular structure of an open human K ATP channel. Proc.Natl.Acad.Sci.USA, 118, 2021
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7S5Z
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![BU of 7s5z by Molmil](/molmil-images/mine/7s5z) | Human KATP channel in open conformation, focused on Kir and one SUR, position 3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | Authors: | Zhao, C, MacKinnon, R. | Deposit date: | 2021-09-12 | Release date: | 2021-12-01 | Last modified: | 2021-12-08 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Molecular structure of an open human K ATP channel. Proc.Natl.Acad.Sci.USA, 118, 2021
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1EXB
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![BU of 1exb by Molmil](/molmil-images/mine/1exb) | STRUCTURE OF THE CYTOPLASMIC BETA SUBUNIT-T1 ASSEMBLY OF VOLTAGE-DEPENDENT K CHANNELS | Descriptor: | KV BETA2 PROTEIN, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM CHANNEL KV1.1 | Authors: | Gulbis, J.M, Zhou, M, Mann, S, MacKinnon, R. | Deposit date: | 2000-05-02 | Release date: | 2000-07-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent K+ channels. Science, 289, 2000
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1BFE
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![BU of 1bfe by Molmil](/molmil-images/mine/1bfe) | THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 | Descriptor: | PSD-95 | Authors: | Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R. | Deposit date: | 1998-05-20 | Release date: | 1998-10-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ. Cell(Cambridge,Mass.), 85, 1996
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1OTU
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![BU of 1otu by Molmil](/molmil-images/mine/1otu) | Structure of the Escherichia coli ClC Chloride channel E148Q mutant and Fab Complex | Descriptor: | CHLORIDE ION, Fab fragment (Heavy chain), Fab fragment (Light chain), ... | Authors: | Dutzler, R, Campbell, E.B, MacKinnon, R. | Deposit date: | 2003-03-23 | Release date: | 2003-04-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Gating the Selectivity Filter in ClC Chloride Channels Science, 300, 2003
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1OTT
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![BU of 1ott by Molmil](/molmil-images/mine/1ott) | Structure of the Escherichia coli ClC Chloride channel E148A mutant and Fab Complex | Descriptor: | CHLORIDE ION, Fab fragment (Heavy chain), Fab fragment (Light chain), ... | Authors: | Dutzler, R, Campbell, E.B, MacKinnon, R. | Deposit date: | 2003-03-23 | Release date: | 2003-04-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Gating the Selectivity Filter in ClC Chloride Channels Science, 300, 2003
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4HPF
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![BU of 4hpf by Molmil](/molmil-images/mine/4hpf) | Structure of the human SLO3 gating ring | Descriptor: | Potassium channel subfamily U member 1 | Authors: | Leonetti, M.D, Yuan, P, MacKinnon, R. | Deposit date: | 2012-10-23 | Release date: | 2012-11-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel. Proc.Natl.Acad.Sci.USA, 109, 2012
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4JTC
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![BU of 4jtc by Molmil](/molmil-images/mine/4jtc) | Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin in Cs+ | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Banerjee, A, Lee, A, Campbell, E, MacKinnon, R. | Deposit date: | 2013-03-23 | Release date: | 2013-06-12 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel. Elife, 2, 2013
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4JTD
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![BU of 4jtd by Molmil](/molmil-images/mine/4jtd) | Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Lys27Met mutant of Charybdotoxin | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ... | Authors: | Banerjee, A, Lee, A, Campbell, E, MacKinnon, R. | Deposit date: | 2013-03-23 | Release date: | 2013-06-12 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel. Elife, 2, 2013
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