7QMR
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![BU of 7qmr by Molmil](/molmil-images/mine/7qmr) | Endothiapepsin in complex with compound TL00150 at room-temperature (temperature ramping up structure 1) | Descriptor: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, DIMETHYL SULFOXIDE, Endothiapepsin, ... | Authors: | Huang, C.Y, Aumonier, S, Wang, M. | Deposit date: | 2021-12-20 | Release date: | 2022-08-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Probing ligand binding of endothiapepsin by `temperature-resolved' macromolecular crystallography. Acta Crystallogr D Struct Biol, 78, 2022
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7QMT
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![BU of 7qmt by Molmil](/molmil-images/mine/7qmt) | Endothiapepsin in complex with compound TL00150 at room-temperature (temperature ramping up structure 3) | Descriptor: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, DIMETHYL SULFOXIDE, Endothiapepsin, ... | Authors: | Huang, C.Y, Aumonier, S, Wang, M. | Deposit date: | 2021-12-20 | Release date: | 2022-08-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Probing ligand binding of endothiapepsin by `temperature-resolved' macromolecular crystallography. Acta Crystallogr D Struct Biol, 78, 2022
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7QMS
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![BU of 7qms by Molmil](/molmil-images/mine/7qms) | Endothiapepsin in complex with compound TL00150 at room-temperature (temperature ramping up structure 2) | Descriptor: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, DIMETHYL SULFOXIDE, Endothiapepsin, ... | Authors: | Huang, C.Y, Aumonier, S, Wang, M. | Deposit date: | 2021-12-20 | Release date: | 2022-08-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Probing ligand binding of endothiapepsin by `temperature-resolved' macromolecular crystallography. Acta Crystallogr D Struct Biol, 78, 2022
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7QMU
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![BU of 7qmu by Molmil](/molmil-images/mine/7qmu) | Endothiapepsin in complex with compound TL00150 at room-temperature (temperature ramping up structure 4) | Descriptor: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, DIMETHYL SULFOXIDE, Endothiapepsin, ... | Authors: | Huang, C.Y, Aumonier, S, Wang, M. | Deposit date: | 2021-12-20 | Release date: | 2022-08-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Probing ligand binding of endothiapepsin by `temperature-resolved' macromolecular crystallography. Acta Crystallogr D Struct Biol, 78, 2022
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7QMV
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![BU of 7qmv by Molmil](/molmil-images/mine/7qmv) | Endothiapepsin in complex with compound TL00150 at room-temperature (temperature ramping up structure 5) | Descriptor: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, DIMETHYL SULFOXIDE, Endothiapepsin, ... | Authors: | Huang, C.Y, Aumonier, S, Wang, M. | Deposit date: | 2021-12-20 | Release date: | 2022-08-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Probing ligand binding of endothiapepsin by `temperature-resolved' macromolecular crystallography. Acta Crystallogr D Struct Biol, 78, 2022
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7QMW
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![BU of 7qmw by Molmil](/molmil-images/mine/7qmw) | Endothiapepsin in complex with compound TL00150 at room-temperature (temperature ramping up structure 6) | Descriptor: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, DIMETHYL SULFOXIDE, Endothiapepsin, ... | Authors: | Huang, C.Y, Aumonier, S, Wang, M. | Deposit date: | 2021-12-20 | Release date: | 2022-08-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Probing ligand binding of endothiapepsin by `temperature-resolved' macromolecular crystallography. Acta Crystallogr D Struct Biol, 78, 2022
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7QMX
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![BU of 7qmx by Molmil](/molmil-images/mine/7qmx) | Endothiapepsin in complex with compound TL00150 at room-temperature (temperature ramping up structure 7) | Descriptor: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, DIMETHYL SULFOXIDE, Endothiapepsin, ... | Authors: | Huang, C.Y, Aumonier, S, Wang, M. | Deposit date: | 2021-12-20 | Release date: | 2022-08-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Probing ligand binding of endothiapepsin by `temperature-resolved' macromolecular crystallography. Acta Crystallogr D Struct Biol, 78, 2022
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7QN0
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![BU of 7qn0 by Molmil](/molmil-images/mine/7qn0) | Endothiapepsin in complex with compound TL00150 at room-temperature (temperature ramping up structure 10) | Descriptor: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, DIMETHYL SULFOXIDE, Endothiapepsin, ... | Authors: | Huang, C.Y, Aumonier, S, Wang, M. | Deposit date: | 2021-12-20 | Release date: | 2022-08-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Probing ligand binding of endothiapepsin by `temperature-resolved' macromolecular crystallography. Acta Crystallogr D Struct Biol, 78, 2022
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7QN2
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![BU of 7qn2 by Molmil](/molmil-images/mine/7qn2) | Endothiapepsin in complex with compound TL00150 at room-temperature (temperature ramping up structure 12) | Descriptor: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, DIMETHYL SULFOXIDE, Endothiapepsin, ... | Authors: | Huang, C.Y, Aumonier, S, Wang, M. | Deposit date: | 2021-12-20 | Release date: | 2022-08-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Probing ligand binding of endothiapepsin by `temperature-resolved' macromolecular crystallography. Acta Crystallogr D Struct Biol, 78, 2022
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4QNN
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![BU of 4qnn by Molmil](/molmil-images/mine/4qnn) | |
6RYP
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![BU of 6ryp by Molmil](/molmil-images/mine/6ryp) | Bacterial membrane enzyme structure by the in meso method at 2.3 A resolution | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Lipoprotein signal peptidase, ... | Authors: | Huang, C.Y, Olatunji, S, Bailey, J, Yu, X, Olieric, V, Wang, M, Caffrey, M. | Deposit date: | 2019-06-11 | Release date: | 2020-01-15 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of lipoprotein signal peptidase II from Staphylococcus aureus complexed with antibiotics globomycin and myxovirescin. Nat Commun, 11, 2020
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7P2L
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![BU of 7p2l by Molmil](/molmil-images/mine/7p2l) | thermostabilised 7TM domain of human mGlu5 receptor bound to photoswitchable ligand alloswitch-1 | Descriptor: | 2-chloranyl-~{N}-[2-methoxy-4-[(~{E})-pyridin-2-yldiazenyl]phenyl]benzamide, Metabotropic glutamate receptor 5,Endolysin,Metabotropic glutamate receptor 5 | Authors: | Huang, C.Y, Vinothkumar, K.R, Lebon, G. | Deposit date: | 2021-07-06 | Release date: | 2021-09-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations. Cell Rep, 36, 2021
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3VMA
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![BU of 3vma by Molmil](/molmil-images/mine/3vma) | Crystal Structure of the Full-Length Transglycosylase PBP1b from Escherichia coli | Descriptor: | MOENOMYCIN, Penicillin-binding protein 1B | Authors: | Huang, C.Y, Sung, M.T, Lai, Y.T, Chou, L.Y, Shih, H.W, Cheng, W.C, Wong, C.H, Ma, C. | Deposit date: | 2011-12-09 | Release date: | 2012-03-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.161 Å) | Cite: | Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli. Proc.Natl.Acad.Sci.USA, 106, 2009
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6RYO
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![BU of 6ryo by Molmil](/molmil-images/mine/6ryo) | Bacterial membrane enzyme structure by the in meso method at 1.9 A resolution | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, GLYCEROL, ... | Authors: | Huang, C.Y, Olatunji, S, Bailey, J, Yu, X, Olieric, V, Wang, M, Caffrey, M. | Deposit date: | 2019-06-11 | Release date: | 2020-01-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.924 Å) | Cite: | Structures of lipoprotein signal peptidase II from Staphylococcus aureus complexed with antibiotics globomycin and myxovirescin. Nat Commun, 11, 2020
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4XNL
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![BU of 4xnl by Molmil](/molmil-images/mine/4xnl) | X-ray structure of AlgE2 | Descriptor: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ... | Authors: | Ma, P, Huang, C.Y, Olieric, V, Diederichs, K, Wang, M, Caffrey, M. | Deposit date: | 2015-01-15 | Release date: | 2015-06-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | In meso in situ serial X-ray crystallography of soluble and membrane proteins. Acta Crystallogr.,Sect.D, 71, 2015
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4XNK
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![BU of 4xnk by Molmil](/molmil-images/mine/4xnk) | X-ray structure of AlgE1 | Descriptor: | (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Alginate production protein AlgE, ... | Authors: | Ma, P, Huang, C.Y, Olieric, V, Diederichs, K, Wang, M, Caffrey, M. | Deposit date: | 2015-01-15 | Release date: | 2015-06-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | In meso in situ serial X-ray crystallography of soluble and membrane proteins. Acta Crystallogr.,Sect.D, 71, 2015
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5YUN
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![BU of 5yun by Molmil](/molmil-images/mine/5yun) | Crystal structure of SSB complexed with myc | Descriptor: | 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, Single-stranded DNA-binding protein | Authors: | Huang, Y.H, Huang, C.Y. | Deposit date: | 2017-11-22 | Release date: | 2018-10-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Crystal structure of SSB complexed with inhibitor myricetin. Biochem. Biophys. Res. Commun., 504, 2018
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4APV
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![BU of 4apv by Molmil](/molmil-images/mine/4apv) | The Klebsiella pneumoniae primosomal PriB protein: identification, crystal structure, and ssDNA binding mode | Descriptor: | PRIMOSOMAL REPLICATION PROTEIN N | Authors: | Lo, Y.H, Huang, Y.H, Hsiao, C.D, Huang, C.Y. | Deposit date: | 2012-04-06 | Release date: | 2012-04-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.095 Å) | Cite: | Crystal Structure and DNA-Binding Mode of Klebsiella Pneumoniae Primosomal Prib Protein. Genes Cells, 17, 2012
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6L0B
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![BU of 6l0b by Molmil](/molmil-images/mine/6l0b) | Crystal structure of dihydroorotase in complex with fluorouracil from Saccharomyces cerevisiae | Descriptor: | 5-FLUOROURACIL, Dihydroorotase, ZINC ION | Authors: | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | Deposit date: | 2019-09-26 | Release date: | 2020-12-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
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6L0G
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![BU of 6l0g by Molmil](/molmil-images/mine/6l0g) | Crystal structure of dihydroorotase in complex with malate at pH6 from Saccharomyces cerevisiae | Descriptor: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | Authors: | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | Deposit date: | 2019-09-26 | Release date: | 2020-12-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.053 Å) | Cite: | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
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6L0A
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![BU of 6l0a by Molmil](/molmil-images/mine/6l0a) | Crystal structure of dihydroorotase in complex with malate at pH7 from Saccharomyces cerevisiae | Descriptor: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | Authors: | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | Deposit date: | 2019-09-26 | Release date: | 2020-12-02 | Last modified: | 2021-12-15 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Structural Analysis of Saccharomyces cerevisiae Dihydroorotase Reveals Molecular Insights into the Tetramerization Mechanism Molecules, 2021
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6EDQ
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![BU of 6edq by Molmil](/molmil-images/mine/6edq) | Crystal Structure of the Light-Gated Anion Channelrhodopsin GtACR1 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Anion channelrhodopsin 1, GLYCEROL | Authors: | Li, H, Huang, C.Y, Wang, M, Zheng, L, Spudich, J.L. | Deposit date: | 2018-08-10 | Release date: | 2019-01-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of a natural light-gated anion channelrhodopsin. Elife, 8, 2019
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6QZH
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![BU of 6qzh by Molmil](/molmil-images/mine/6qzh) | Structure of the human CC Chemokine Receptor 7 in complex with the intracellular allosteric antagonist Cmp2105 and the insertion protein Sialidase NanA | Descriptor: | 3-[[4-[[(1~{R})-2,2-dimethyl-1-(5-methylfuran-2-yl)propyl]amino]-1,1-bis(oxidanylidene)-1,2,5-thiadiazol-3-yl]amino]-~{N},~{N},6-trimethyl-2-oxidanyl-benzamide, C-C chemokine receptor type 7,Sialidase A,C-C chemokine receptor type 7, D(-)-TARTARIC ACID, ... | Authors: | Jaeger, K, Bruenle, S, Weinert, T, Guba, W, Muehle, J, Miyazaki, T, Weber, M, Furrer, A, Haenggi, N, Tetaz, T, Huang, C.Y, Mattle, D, Vonach, J.M, Gast, A, Kuglstatter, A, Rudolph, M.G, Nogly, P, Benz, J, Dawson, R.J.P, Standfuss, J. | Deposit date: | 2019-03-11 | Release date: | 2019-09-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Basis for Allosteric Ligand Recognition in the Human CC Chemokine Receptor 7. Cell, 178, 2019
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8WQ9
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![BU of 8wq9 by Molmil](/molmil-images/mine/8wq9) | |
7D8J
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![BU of 7d8j by Molmil](/molmil-images/mine/7d8j) | S. aureus SsbB with 5-FU | Descriptor: | 5-FLUOROURACIL, Single-stranded DNA-binding protein | Authors: | Lin, E.S, Huang, Y.H, Huang, C.Y. | Deposit date: | 2020-10-08 | Release date: | 2020-12-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Crystal structure of the single-stranded DNA-binding protein SsbB in complex with the anticancer drug 5-fluorouracil: Extension of the 5-fluorouracil interactome to include the oligonucleotide/oligosaccharide-binding fold protein Biochem.Biophys.Res.Commun., 534, 2020
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