3VMA

Crystal Structure of the Full-Length Transglycosylase PBP1b from Escherichia coli

Replaces:  3FWM

Summary for 3VMA

• Entry DOI: 10.2210/pdb3vma/pdb
• Related: 3FWL
• Descriptor: Penicillin-binding protein 1B, MOENOMYCIN (3 entities in total)
• Functional Keywords: bacterial cell wall synthesis, penicillin-binding protein, antibiotics design, pbp3, mipa, mlta, ftsn, membrane, transferase, hydrolase-antibiotic complex, hydrolase/antibiotic
• Biological source: Escherichia coli
• Cellular location: Cell inner membrane; Single-pass type II membrane protein: P02919
• Total number of polymer chains: 1
• Total formula weight: 87163.48

Authors

Huang, C.Y.,Sung, M.T.,Lai, Y.T.,Chou, L.Y.,Shih, H.W.,Cheng, W.C.,Wong, C.H.,Ma, C. (deposition date: 2011-12-09, release date: 2012-03-14, Last modification date: 2023-11-08)

• Primary citation: Sung, M.T.,Lai, Y.T.,Huang, C.Y.,Chou, L.Y.,Shih, H.W.,Cheng, W.C.,Wong, C.H.,Ma, C.; Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli.; Proc.Natl.Acad.Sci.USA, 106:8824-8829, 2009; PubMed: 19458048; DOI: 10.1073/pnas.0904030106

Experimental method

X-RAY DIFFRACTION (2.161 Å)