3VMA

Crystal Structure of the Full-Length Transglycosylase PBP1b from Escherichia coli

Replaces:  3FWM

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008233	molecular_function	peptidase activity
A	0008658	molecular_function	penicillin binding
A	0008955	molecular_function	peptidoglycan glycosyltransferase activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0046677	biological_process	response to antibiotic

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE M0E A 901

Chain	Residue
A	GLU233
A	VAL354
A	LYS355
A	ALA357
A	SER358
A	ILE359
A	GLN271
A	LYS274
A	ASN275
A	GLU281
A	ARG286
A	TYR315
A	GLN318
A	GLU323

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	91
Details	Region: {"description":"UvrB domain 2 homolog"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	292
Details	Region: {"description":"Transpeptidase"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Active site: {"description":"Proton donor; for transglycosylase activity","evidences":[{"source":"PubMed","id":"10564478","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Active site: {"description":"Acyl-ester intermediate; for transpeptidase activity","evidences":[{"source":"PubMed","id":"10564478","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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