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1MAE
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BU of 1mae by Molmil
The Active Site Structure of Methylamine Dehydrogenase: Hydrazines Identify C6 as the Reactive Site of the Tryptophan Derived Quinone Cofactor
Descriptor: METHYLAMINE DEHYDROGENASE (HEAVY SUBUNIT), METHYLAMINE DEHYDROGENASE (LIGHT SUBUNIT), NITROGEN MOLECULE
Authors:Huizinga, E.G, Vellieux, F.M.D, Hol, W.G.J.
Deposit date:1992-05-20
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Active site structure of methylamine dehydrogenase: hydrazines identify C6 as the reactive site of the tryptophan-derived quinone cofactor.
Biochemistry, 31, 1992
1MAF
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The Active Site Structure of Methylamine Dehydrogenase: Hydrazines Identify C6 as the Reactive Site of the Tryptophan Derived Quinone Cofactor
Descriptor: METHYLAMINE DEHYDROGENASE (HEAVY SUBUNIT), METHYLAMINE DEHYDROGENASE (LIGHT SUBUNIT), NITROGEN MOLECULE
Authors:Huizinga, E.G, Vellieux, F.M.D, Hol, W.G.J.
Deposit date:1992-05-20
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Active site structure of methylamine dehydrogenase: hydrazines identify C6 as the reactive site of the tryptophan-derived quinone cofactor.
Biochemistry, 31, 1992
1NOP
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BU of 1nop by Molmil
Crystal structure of human tyrosyl-DNA phosphodiesterase (Tdp1) in complex with vanadate, DNA and a human topoisomerase I-derived peptide
Descriptor: 5'-D(*AP*GP*AP*GP*TP*T)-3', VANADATE ION, topoisomerase I-derived peptide, ...
Authors:Davies, D.R, Interthal, H, Champoux, J.J, Hol, W.G.J.
Deposit date:2003-01-16
Release date:2003-03-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a transition state mimic for Tdp1 assembled from vanadate, DNA, and a topoisomerase I-derived peptide
Chem.Biol., 10, 2003
1RL4
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BU of 1rl4 by Molmil
Plasmodium falciparum peptide deformylase complex with inhibitor
Descriptor: (2R)-2-{[FORMYL(HYDROXY)AMINO]METHYL}HEXANOIC ACID, 2-{N'-[2-(5-AMINO-1-PHENYLCARBAMOYL-PENTYLCARBAMOYL)-HEXYL]-HYDRAZINOMETHYL}-HEXANOIC ACID(5-AMINO-1-PHENYLCARBAMOYL-PENTYL)-AMIDE, COBALT (II) ION, ...
Authors:Robien, M.A, Nguyen, K.T, Kumar, A, Hirsh, I, Turley, S, Pei, D, Hol, W.G.J.
Deposit date:2003-11-24
Release date:2003-12-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:An improved crystal form of Plasmodium falciparum peptide deformylase.
Protein Sci., 13, 2004
1HC1
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BU of 1hc1 by Molmil
CRYSTAL STRUCTURE OF HEXAMERIC HAEMOCYANIN FROM PANULIRUS INTERRUPTUS REFINED AT 3.2 ANGSTROMS RESOLUTION
Descriptor: ARTHROPODAN HEMOCYANIN, COPPER (II) ION
Authors:Volbeda, A, Hol, W.G.J.
Deposit date:1991-05-15
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of hexameric haemocyanin from Panulirus interruptus refined at 3.2 A resolution.
J.Mol.Biol., 209, 1989
1HCY
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BU of 1hcy by Molmil
CRYSTAL STRUCTURE OF HEXAMERIC HAEMOCYANIN FROM PANULIRUS INTERRUPTUS REFINED AT 3.2 ANGSTROMS RESOLUTION
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ARTHROPODAN HEMOCYANIN, COPPER (II) ION
Authors:Volbeda, A, Hol, W.G.J.
Deposit date:1991-05-15
Release date:1994-01-31
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of hexameric haemocyanin from Panulirus interruptus refined at 3.2 A resolution.
J.Mol.Biol., 209, 1989
1QCB
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BU of 1qcb by Molmil
ESCHERICHIA COLI HEAT LABILE ENTEROTOXIN TYPE IIB B-PENTAMER
Descriptor: PROTEIN (HEAT LABILE ENTEROTOXIN TYPE IIB B-PENTAMER)
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1999-04-30
Release date:2003-06-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of the B-Pentamer from E. coli Enterotoxin LT-IIb
To be Published
1P2P
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BU of 1p2p by Molmil
STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A2 AT 2.6 ANGSTROMS RESOLUTION AND COMPARISON WITH BOVINE PHOSPHOLIPASE A2
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Dijkstra, B.W, Renetseder, R, Kalk, K.H, Hol, W.G.J, Drenth, J.
Deposit date:1983-06-27
Release date:1983-09-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of porcine pancreatic phospholipase A2 at 2.6 A resolution and comparison with bovine phospholipase A2.
J.Mol.Biol., 168, 1983
1CHQ
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BU of 1chq by Molmil
SURPRISING LEADS FOR A CHOLERA TOXIN RECEPTOR BINDING ANTAGONIST; CRYSTALLOGRAPHIC STUDIES OF CTB MUTANTS
Descriptor: CHOLERA TOXIN B PENTAMER
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1995-02-15
Release date:1996-03-08
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Surprising leads for a cholera toxin receptor-binding antagonist: crystallographic studies of CTB mutants.
Structure, 3, 1995
1CHP
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BU of 1chp by Molmil
SURPRISING LEADS FOR A CHOLERA TOXIN RECEPTOR BINDING ANTAGONIST; CRYSTALLOGRAPHIC STUDIES OF CTB MUTANTS
Descriptor: CHLORIDE ION, CHOLERA TOXIN B PENTAMER
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1995-02-15
Release date:1996-03-08
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Surprising leads for a cholera toxin receptor-binding antagonist: crystallographic studies of CTB mutants.
Structure, 3, 1995
1MU9
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BU of 1mu9 by Molmil
Crystal Structure of a Human Tyrosyl-DNA Phosphodiesterase (Tdp1)-Vanadate Complex
Descriptor: GLYCEROL, Tyrosyl-DNA Phosphodiesterase, VANADATE ION
Authors:Davies, D.R, Interthal, H, Champoux, J.J, Hol, W.G.J.
Deposit date:2002-09-23
Release date:2003-01-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Insights Into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate- and Tungstate-Inhibited Structures
J.Mol.Biol., 324, 2002
1MU7
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BU of 1mu7 by Molmil
Crystal Structure of a Human Tyrosyl-DNA Phosphodiesterase (Tdp1)-Tungstate Complex
Descriptor: GLYCEROL, TUNGSTATE(VI)ION, Tyrosyl-DNA Phosphodiesterase
Authors:Davies, D.R, Interthal, H, Champoux, J.J, Hol, W.G.J.
Deposit date:2002-09-23
Release date:2003-01-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insights Into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate- and Tungstate-Inhibited Structures
J.Mol.Biol., 324, 2003
1EEI
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BU of 1eei by Molmil
CHOLERA TOXIN B-PENTAMER COMPLEXED WITH METANITROPHENYL-ALPHA-D-GALACTOSE
Descriptor: 3-nitrophenyl alpha-D-galactopyranoside, PROTEIN (CHOLERA TOXIN B)
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:2000-01-31
Release date:2000-02-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Exploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives.
Acta Crystallogr.,Sect.D, 57, 2001
1U8R
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BU of 1u8r by Molmil
Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions
Descriptor: COBALT (II) ION, Iron-dependent repressor ideR, SODIUM ION, ...
Authors:Wisedchaisri, G, Holmes, R.K, Hol, W.G.J.
Deposit date:2004-08-06
Release date:2004-10-05
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions.
J.Mol.Biol., 342, 2004
1LTS
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BU of 1lts by Molmil
REFINED STRUCTURE OF E. COLI HEAT LABILE ENTEROTOXIN, A CLOSE RELATIVE OF CHOLERA TOXIN
Descriptor: HEAT-LABILE ENTEROTOXIN, SUBUNIT A, SUBUNIT B
Authors:Sixma, T.K, Hol, W.G.J.
Deposit date:1992-07-15
Release date:1994-01-31
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Refined structure of Escherichia coli heat-labile enterotoxin, a close relative of cholera toxin.
J.Mol.Biol., 230, 1993
1LTA
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BU of 1lta by Molmil
2.2 ANGSTROMS CRYSTAL STRUCTURE OF E. COLI HEAT-LABILE ENTEROTOXIN (LT) WITH BOUND GALACTOSE
Descriptor: HEAT-LABILE ENTEROTOXIN, SUBUNIT A, SUBUNIT B, ...
Authors:Merritt, E.A, Sixma, T.K, Kalk, K.H, Van Zanten, B.A.M, Hol, W.G.J.
Deposit date:1993-09-15
Release date:1994-01-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Galactose-binding site in Escherichia coli heat-labile enterotoxin (LT) and cholera toxin (CT).
Mol.Microbiol., 13, 1994
1SYR
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BU of 1syr by Molmil
Initial Structural Analysis of Plasmodium falciparum thioredoxin
Descriptor: thioredoxin
Authors:Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-04-01
Release date:2004-04-13
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Initial Structural Analysis of Plasmodium falciparum thioredoxin
To be Published
1TC5
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BU of 1tc5 by Molmil
Structural Analysis of a probable eukaryotic D-amino acid tRNA deacylase
Descriptor: Probable eukaryotic D-amino acid tRNA deacylase, LMAJ005534AAA
Authors:Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-05-20
Release date:2004-06-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural analysis of LMAJ005534AAA, a probable eukaryotic D-amino acid tRNA deacylase from Leishmania major
To be Published
1UV7
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BU of 1uv7 by Molmil
periplasmic domain of EpsM from Vibrio cholerae
Descriptor: GENERAL SECRETION PATHWAY PROTEIN M
Authors:Abendroth, J, Hol, W.G.J.
Deposit date:2004-01-15
Release date:2004-04-23
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Crystal Structure of the Periplasmic Domain of the Type II Secretion System Protein Epsm from Vibrio Cholerae: The Simplest Version of the Ferredoxin Fold
J.Mol.Biol., 338, 2004
1LVL
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BU of 1lvl by Molmil
THE REFINED STRUCTURE OF PSEUDOMONAS PUTIDA LIPOAMIDE DEHYDROGENASE COMPLEXED WITH NAD+ AT 2.45 ANGSTROMS RESOLUTION
Descriptor: DIHYDROLIPOAMIDE DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Mattevi, A, Hol, W.G.J.
Deposit date:1992-12-16
Release date:1994-01-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The refined crystal structure of Pseudomonas putida lipoamide dehydrogenase complexed with NAD+ at 2.45 A resolution.
Proteins, 13, 1992
1NOL
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BU of 1nol by Molmil
OXYGENATED HEMOCYANIN (SUBUNIT TYPE II)
Descriptor: CALCIUM ION, COPPER (II) ION, HEMOCYANIN (SUBUNIT TYPE II), ...
Authors:Hazes, B, Hol, W.G.J.
Deposit date:1995-10-17
Release date:1996-03-08
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of deoxygenated Limulus polyphemus subunit II hemocyanin at 2.18 A resolution: clues for a mechanism for allosteric regulation.
Protein Sci., 2, 1993
1HTL
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BU of 1htl by Molmil
MUTATION OF A BURIED RESIDUE CAUSES LACK OF ACTIVITY BUT NO CONFORMATIONAL CHANGE: CRYSTAL STRUCTURE OF E. COLI HEAT-LABILE ENTEROTOXIN MUTANT VAL 97--> LYS
Descriptor: HEAT-LABILE ENTEROTOXIN, SUBUNIT A, SUBUNIT B
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1995-02-15
Release date:1995-04-20
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutation of a buried residue causes loss of activity but no conformational change in the heat-labile enterotoxin of Escherichia coli.
Nat.Struct.Biol., 2, 1995
1LTG
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BU of 1ltg by Molmil
THE ARG7LYS MUTANT OF HEAT-LABILE ENTEROTOXIN EXHIBITS GREAT FLEXIBILITY OF ACTIVE SITE LOOP 47-56 OF THE A SUBUNIT
Descriptor: HEAT-LABILE ENTEROTOXIN
Authors:Van Den Akker, F, Hol, W.G.J.
Deposit date:1995-06-13
Release date:1995-09-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Arg7Lys mutant of heat-labile enterotoxin exhibits great flexibility of active site loop 47-56 of the A subunit.
Biochemistry, 34, 1995
1P9W
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BU of 1p9w by Molmil
Crystal Structure of Vibrio cholerae putative NTPase EpsE
Descriptor: General secretion pathway protein E, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ZINC ION
Authors:Robien, M.A, Krumm, B.E, Sandkvist, M, Hol, W.G.J.
Deposit date:2003-05-12
Release date:2003-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the extracellular protein secretion NTPase EpsE of Vibrio cholerae
J.Mol.Biol., 333, 2003
1M66
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Crystal Structure of Leishmania mexicana GPDH Complexed with Inhibitor 2-bromo-6-chloro-purine
Descriptor: 2-BROMO-6-CHLORO-PURINE, Glycerol-3-phosphate dehydrogenase, PALMITIC ACID
Authors:Choe, J, Suresh, S, Wisedchaisri, G, Kennedy, K.J, Gelb, M.H, Hol, W.G.J.
Deposit date:2002-07-12
Release date:2002-12-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Anomalous differences of light elements in determining precise binding modes of ligands to glycerol-3-phosphate dehydrogenase
Chem.Biol., 9, 2002

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