1M66

Crystal Structure of Leishmania mexicana GPDH Complexed with Inhibitor 2-bromo-6-chloro-purine

Summary for 1M66

Entry DOI	10.2210/pdb1m66/pdb
Related	1evy 1evz 1m67
Descriptor	Glycerol-3-phosphate dehydrogenase, 2-BROMO-6-CHLORO-PURINE, PALMITIC ACID, ... (4 entities in total)
Functional Keywords	nad-binding motif, oxidoreductase
Biological source	Leishmania mexicana
Cellular location	Glycosome: P90551
Total number of polymer chains	1
Total formula weight	39807.71
Authors	Choe, J.,Suresh, S.,Wisedchaisri, G.,Kennedy, K.J.,Gelb, M.H.,Hol, W.G.J. (deposition date: 2002-07-12, release date: 2002-12-11, Last modification date: 2024-02-14)
Primary citation	Choe, J.,Suresh, S.,Wisedchaisri, G.,Kennedy, K.J.,Gelb, M.H.,Hol, W.G.J. Anomalous differences of light elements in determining precise binding modes of ligands to glycerol-3-phosphate dehydrogenase Chem.Biol., 9:1189-1197, 2002 Cited by PubMed: 12445769 DOI: 10.1016/S1074-5521(02)00243-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation