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8SEL
Type IIIb beta-amyloid 40 Filaments from Down Syndrome
Descriptor:
Amyloid-beta protein 40
Authors:
Hoq, M.R
,
Vago, F.S
,
Bharath, S.R
,
Jiang, W.
Deposit date:
2023-04-10
Release date:
2024-04-03
Last modified:
2024-06-26
Method:
ELECTRON MICROSCOPY (3.8 Å)
Cite:
Cryo-EM structures of amyloid-beta and tau filaments in Down syndrome.
Nat.Struct.Mol.Biol., 31, 2024
8CG3
Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 1)
Descriptor:
TAR DNA-binding protein 43
Authors:
Arseni, D
,
Ryskeldi-Falcon, B.
Deposit date:
2023-02-03
Release date:
2023-08-02
Last modified:
2023-08-30
Method:
ELECTRON MICROSCOPY (2.39 Å)
Cite:
TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP.
Nature, 620, 2023
7UN5
Structure of Type II Prion filaments from Gerstmann-Straussler-Scheinker disease
Descriptor:
Major prion protein
Authors:
Ozcan, K.A
,
Hoq, M.R
,
Bharath, S.R
,
Jiang, W.
Deposit date:
2022-04-08
Release date:
2022-07-27
Last modified:
2024-03-27
Method:
ELECTRON MICROSCOPY (3.13 Å)
Cite:
Cryo-EM structures of prion protein filaments from Gerstmann-Straussler-Scheinker disease.
Acta Neuropathol, 144, 2022
7UMQ
Structure of Type I Prion filaments from Gerstmann-Straussler-Scheinker disease
Descriptor:
Major prion protein
Authors:
Ozcan, K.A
,
Hoq, M.R
,
Bharath, S.R
,
Jiang, W.
Deposit date:
2022-04-07
Release date:
2022-07-27
Last modified:
2024-03-27
Method:
ELECTRON MICROSCOPY (3.29 Å)
Cite:
Cryo-EM structures of prion protein filaments from Gerstmann-Straussler-Scheinker disease.
Acta Neuropathol, 144, 2022
7QWL
TMEM106B filaments with Fold IIb from Multiple system atrophy (case 19)
Descriptor:
Transmembrane protein 106B
Authors:
Lovestam, S
,
Schweighauser, M
,
Scheres, S.H.W.
Deposit date:
2022-01-25
Release date:
2022-03-09
Last modified:
2022-05-25
Method:
ELECTRON MICROSCOPY (3.47 Å)
Cite:
Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVC
TMEM106B filaments with Fold I from Alzheimer's disease (case 1)
Descriptor:
Transmembrane protein 106B
Authors:
Lovestam, S
,
Schweighauser, M
,
Scheres, S.H.W.
Deposit date:
2022-01-21
Release date:
2022-03-09
Last modified:
2022-05-25
Method:
ELECTRON MICROSCOPY (2.64 Å)
Cite:
Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVF
TMEM106B filaments with Fold I-d from Multiple system atrophy (case 18)
Descriptor:
Transmembrane protein 106B
Authors:
Lovestam, S
,
Schweighauser, M
,
Scheres, S.H.W.
Deposit date:
2022-01-21
Release date:
2022-03-09
Last modified:
2022-05-25
Method:
ELECTRON MICROSCOPY (3.64 Å)
Cite:
Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWG
TMEM106B filaments with Fold IIa from Multiple system atrophy (case 19)
Descriptor:
Transmembrane protein 106B
Authors:
Lovestam, S
,
Schweighauser, M
,
Scheres, S.H.W.
Deposit date:
2022-01-25
Release date:
2022-03-09
Last modified:
2022-05-25
Method:
ELECTRON MICROSCOPY (3.38 Å)
Cite:
Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWM
TMEM106B filaments with Fold III from Multiple system atrophy (case 17)
Descriptor:
Transmembrane protein 106B
Authors:
Lovestam, S
,
Schweighauser, M
,
Scheres, S.H.W.
Deposit date:
2022-01-25
Release date:
2022-03-09
Last modified:
2022-05-25
Method:
ELECTRON MICROSCOPY (2.76 Å)
Cite:
Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
9CZI
Paired helical tau filaments in dominantly inherited Alzheimer disease with cotton wool plaques
Descriptor:
Microtubule-associated protein tau
Authors:
Hoq, M.R
,
Vago, F.S
,
Ozcan, K.A
,
Bharath, S.R.
Deposit date:
2024-08-05
Release date:
2024-10-02
Method:
ELECTRON MICROSCOPY (3 Å)
Cite:
Cryo-EM structures of cotton wool plaques' amyloid beta and of tau filaments in dominantly inherited Alzheimer disease.
Acta Neuropathol, 148, 2024
9CZN
Type Ic amyloid-beta 42 filaments in dominantly inherited Alzheimer disease with cotton wool plaques
Descriptor:
Amyloid-beta protein 42
Authors:
Hoq, M.R
,
Vago, F.S
,
Ozcan, K.A
,
Bharath, S.R.
Deposit date:
2024-08-05
Release date:
2024-10-02
Method:
ELECTRON MICROSCOPY (2.6 Å)
Cite:
Cryo-EM structures of cotton wool plaques' amyloid beta and of tau filaments in dominantly inherited Alzheimer disease.
Acta Neuropathol, 148, 2024
9CZP
Type Id amyloid-beta 42 filaments in dominantly inherited Alzheimer disease with cotton wool plaques
Descriptor:
Amyloid-beta protein 42
Authors:
Hoq, M.R
,
Vago, F.S
,
Ozcan, K.A
,
Bharath, S.R.
Deposit date:
2024-08-05
Release date:
2024-10-02
Method:
ELECTRON MICROSCOPY (3.3 Å)
Cite:
Cryo-EM structures of cotton wool plaques' amyloid beta and of tau filaments in dominantly inherited Alzheimer disease.
Acta Neuropathol, 148, 2024
9CZL
Straight tau filaments in dominantly inherited Alzheimer disease with cotton wool plaques
Descriptor:
Isoform Tau-C of Microtubule-associated protein tau
Authors:
Hoq, M.R
,
Vago, F.S
,
Ozcan, K.A
,
Bharath, S.R.
Deposit date:
2024-08-05
Release date:
2024-10-02
Method:
ELECTRON MICROSCOPY (2.9 Å)
Cite:
Cryo-EM structures of cotton wool plaques' amyloid beta and of tau filaments in dominantly inherited Alzheimer disease.
Acta Neuropathol, 148, 2024
7MKF
Paired helical tau filament extracted from PrP-CAA Patient brain tissue | tau filament | PHF Tau
Descriptor:
Isoform Tau-F of Microtubule-associated protein tau
Authors:
Hoq, M.R.
Deposit date:
2021-04-23
Release date:
2021-07-28
Last modified:
2024-05-29
Method:
ELECTRON MICROSCOPY (3 Å)
Cite:
Structure of Tau filaments in Prion protein amyloidoses.
Acta Neuropathol, 142, 2021
7MKH
Paired helical tau filament extracted from GSS Patient brain tissue | tau filament from Gerstmann Straussler Scheinker disease | PHF Tau
Descriptor:
Isoform Tau-F of Microtubule-associated protein tau
Authors:
Hoq, M.R.
Deposit date:
2021-04-23
Release date:
2021-07-28
Last modified:
2024-05-29
Method:
ELECTRON MICROSCOPY (3.3 Å)
Cite:
Structure of Tau filaments in Prion protein amyloidoses.
Acta Neuropathol, 142, 2021
7MKG
Straight tau filament extracted from PrP-CAA Patient brain tissue | tau filament | SF Tau
Descriptor:
Isoform Tau-F of Microtubule-associated protein tau
Authors:
Hoq, M.R.
Deposit date:
2021-04-23
Release date:
2021-07-28
Last modified:
2024-05-29
Method:
ELECTRON MICROSCOPY (3.07 Å)
Cite:
Structure of Tau filaments in Prion protein amyloidoses.
Acta Neuropathol, 142, 2021
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PDB entries from 2024-10-30