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7E62
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BU of 7e62 by Molmil
Mouse TAB2 NZF in complex with Lys6-linked diubiquitin
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, TGF-beta-activated kinase 1 and MAP3K7-binding protein 2, Ubiquitin, ...
Authors:Sato, Y, Li, Y, Okatsu, K, Fukai, S.
Deposit date:2021-02-21
Release date:2021-08-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural basis for specific recognition of K6-linked polyubiquitin chains by the TAB2 NZF domain.
Biophys.J., 120, 2021
6J6X
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BU of 6j6x by Molmil
Crystal structure of apo GGTaseIII
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Geranylgeranyl transferase type-2 subunit beta, MAGNESIUM ION, ...
Authors:Goto-Ito, S, Yamagata, A, Sato, Y, Fukai, S.
Deposit date:2019-01-16
Release date:2020-01-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.962 Å)
Cite:Crystal structure of apo GGTaseIII
To Be Published
6J74
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BU of 6j74 by Molmil
Complex of GGTaseIII and full-length Ykt6
Descriptor: Geranylgeranyl transferase type-2 subunit beta, PHOSPHATE ION, Protein prenyltransferase alpha subunit repeat-containing protein 1, ...
Authors:Goto-Ito, S, Yamagata, A, Sato, Y, Fukai, S.
Deposit date:2019-01-16
Release date:2020-01-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.212 Å)
Cite:Complex of GGTaseIII and full-length Ykt6
To Be Published
6J7F
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BU of 6j7f by Molmil
Complex of GGTaseIII, farnesyl-Ykt6 (C-terminal methylated), and GGPP
Descriptor: DIPHOSPHATE, FARNESYL, GERAN-8-YL GERAN, ...
Authors:Goto-Ito, S, Yamagata, A, Sato, Y, Fukai, S.
Deposit date:2019-01-18
Release date:2020-01-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.883 Å)
Cite:Complex of GGTaseIII, farnesyl-Ykt6 (C-terminal methylated), and GGPP
To Be Published
6J7X
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BU of 6j7x by Molmil
Complex of GGTaseIII, farnesyl-Ykt6, and GGPP
Descriptor: FORMIC ACID, GERANYLGERANYL DIPHOSPHATE, Geranylgeranyl transferase type-2 subunit beta, ...
Authors:Goto-Ito, S, Yamagata, A, Sato, Y, Fukai, S.
Deposit date:2019-01-18
Release date:2020-01-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Complex of GGTaseIII, farnesyl-Ykt6 (C-terminal methylated), and GGPP
To Be Published
6IXG
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BU of 6ixg by Molmil
Crystal structure of native apo SH3BP5 (P41)
Descriptor: SH3 domain-binding protein 5
Authors:Goto-Ito, S, Yamagata, A, Sato, Y, Fukai, S.
Deposit date:2018-12-10
Release date:2019-03-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.801 Å)
Cite:Structural basis of guanine nucleotide exchange for Rab11 by SH3BP5.
Life Sci Alliance, 2, 2019
5XGC
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BU of 5xgc by Molmil
Crystal structure of SmgGDS-558
Descriptor: Rap1 GTPase-GDP dissociation stimulator 1
Authors:Shimizu, H, Toma-Fukai, S, Shimizu, T.
Deposit date:2017-04-13
Release date:2017-06-28
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based analysis of the guanine nucleotide exchange factor SmgGDS reveals armadillo-repeat motifs and key regions for activity and GTPase binding
J. Biol. Chem., 292, 2017
3VU8
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BU of 3vu8 by Molmil
Metionyl-tRNA synthetase from Thermus thermophilus complexed with methionyl-adenylate analogue
Descriptor: Methionine--tRNA ligase, N-[METHIONYL]-N'-[ADENOSYL]-DIAMINOSULFONE, ZINC ION
Authors:Konno, M, Kato-Murayama, M, Toma-Fukai, S, Uchikawa, E, Nureki, O, Yokoyama, S.
Deposit date:2012-06-22
Release date:2013-06-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The modeling of structures of specific conformation of homosysteine-AMP leading to thiolactone-formation on class Ia aminoacyl-tRNA synthetases
To be Published
4WU7
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BU of 4wu7 by Molmil
HLA-A24 in complex with HIV-1 Nef134-8(2F)
Descriptor: 8-Mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Shimizu, A, Yamagata, A, Fukai, S, Iwamoto, A.
Deposit date:2014-10-31
Release date:2015-05-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.297 Å)
Cite:Crystal structure of Nef134-8 epitope presented by HLA-A24
To Be Published
1VFG
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BU of 1vfg by Molmil
Crystal structure of tRNA nucleotidyltransferase complexed with a primer tRNA and an incoming ATP analog
Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, RNA (75-MER), poly A polymerase
Authors:Tomita, K, Fukai, S, Ishitani, R, Ueda, T, Takeuchi, N, Vassylyev, D.G, Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-04-13
Release date:2004-08-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for template-independent RNA polymerization.
Nature, 430, 2004
5WQJ
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BU of 5wqj by Molmil
Crystal structure of 3-Mercaptopyruvate Sulfurtransferase(3MST) in complex with compound1
Descriptor: 2-[2-[(4-oxidanylidene-3~{H}-quinazolin-2-yl)sulfanyl]ethanoylamino]thiophene-3-carboxamide, SODIUM ION, Sulfurtransferase
Authors:Suwanai, Y, Toma-Fukai, S, Shimizu, T.
Deposit date:2016-11-27
Release date:2017-09-06
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide
Sci Rep, 7, 2017
5WQK
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BU of 5wqk by Molmil
Crystal structure of 3-Mercaptopyruvate Sulfurtransferase(3MST) in complex with compound1
Descriptor: 4-methyl-2-(2-naphthalen-1-yl-2-oxidanylidene-ethyl)sulfanyl-1~{H}-pyrimidin-6-one, SODIUM ION, Sulfurtransferase
Authors:Suwanai, Y, Toma-Fukai, S, Shimizu, T.
Deposit date:2016-11-27
Release date:2017-09-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide
Sci Rep, 7, 2017
5ZHX
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BU of 5zhx by Molmil
Crystal structure of SmgGDS-558 and farnesylated RhoA complex
Descriptor: FARNESYL, Rap1 GTPase-GDP dissociation stimulator 1, Transforming protein RhoA
Authors:Shimizu, H, Toma-Fukai, S, Shimizu, T.
Deposit date:2018-03-13
Release date:2018-09-05
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:GEF mechanism revealed by the structure of SmgGDS-558 and farnesylated RhoA complex and its implication for a chaperone mechanism.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1WY5
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BU of 1wy5 by Molmil
Crystal structure of isoluecyl-tRNA lysidine synthetase
Descriptor: Hypothetical UPF0072 protein AQ_1887
Authors:Nakanishi, K, Fukai, S, Ikeuchi, Y, Soma, A, Sekine, Y, Suzuki, T, Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-02-06
Release date:2005-05-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural basis for lysidine formation by ATP pyrophosphatase accompanied by a lysine-specific loop and a tRNA-recognition domain.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2YVX
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BU of 2yvx by Molmil
Crystal structure of magnesium transporter MgtE
Descriptor: MAGNESIUM ION, Mg2+ transporter MgtE
Authors:Hattori, M, Tanaka, Y, Fukai, S, Ishitani, R, Nureki, O.
Deposit date:2007-04-18
Release date:2007-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the MgtE Mg(2+) transporter
Nature, 448, 2007
2YVZ
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BU of 2yvz by Molmil
Crystal structure of magnesium transporter MgtE cytosolic domain, Mg2+-free form
Descriptor: Mg2+ transporter MgtE
Authors:Hattori, M, Tanaka, Y, Fukai, S, Ishitani, R, Nureki, O.
Deposit date:2007-04-18
Release date:2007-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Crystal structure of the MgtE Mg(2+) transporter
Nature, 448, 2007
2YVY
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BU of 2yvy by Molmil
Crystal structure of magnesium transporter MgtE cytosolic domain, Mg2+ bound form
Descriptor: MAGNESIUM ION, Mg2+ transporter MgtE
Authors:Hattori, M, Tanaka, Y, Fukai, S, Ishitani, R, Nureki, O.
Deposit date:2007-04-18
Release date:2007-09-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the MgtE Mg(2+) transporter
Nature, 448, 2007
3X0D
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BU of 3x0d by Molmil
Crystal structure of C.elegans PRMT7 in complex with SAH (P43212)
Descriptor: Protein arginine N-methyltransferase 7, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Hasegawa, M, Toma-Fukai, S, Shimizu, T.
Deposit date:2014-10-10
Release date:2014-10-29
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Protein arginine methyltransferase 7 has a novel homodimer-like structure formed by tandem repeats
Febs Lett., 588, 2014
3WST
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BU of 3wst by Molmil
Crystal structure of C.elegans PRMT7 in complex with SAH(P31)
Descriptor: PHOSPHATE ION, Protein arginine N-methyltransferase 7, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Hasegawa, M, Toma-fukai, S, Shimizu, T.
Deposit date:2014-03-21
Release date:2014-04-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Protein arginine methyltransferase 7 has a novel homodimer-like structure formed by tandem repeats
Febs Lett., 588, 2014
5XIT
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BU of 5xit by Molmil
Crystal structure of RNF168 UDM1 in complex with Lys63-linked diubiquitin, form II
Descriptor: E3 ubiquitin-protein ligase RNF168, GLYCEROL, PRASEODYMIUM ION, ...
Authors:Takahashi, T.S, Sato, Y, Fukai, S.
Deposit date:2017-04-27
Release date:2018-03-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168.
Nat Commun, 9, 2018
5XIS
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BU of 5xis by Molmil
Crystal structure of RNF168 UDM1 in complex with Lys63-linked diubiquitin, form I
Descriptor: E3 ubiquitin-protein ligase RNF168, MAGNESIUM ION, Ubiquitin-40S ribosomal protein S27a, ...
Authors:Takahashi, T.S, Sato, Y, Fukai, S.
Deposit date:2017-04-27
Release date:2018-03-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168.
Nat Commun, 9, 2018
5YDK
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BU of 5ydk by Molmil
Crystal structure of RNF168 UDM1 in complex with Lys63-linked diubiquitin, tetrameric form
Descriptor: E3 ubiquitin-protein ligase RNF168, GLYCEROL, Ubiquitin-40S ribosomal protein S27a
Authors:Takahashi, T.S, Sato, Y, Fukai, S.
Deposit date:2017-09-13
Release date:2018-03-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.505 Å)
Cite:Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168
Nat Commun, 9, 2018
5XIU
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BU of 5xiu by Molmil
Crystal structure of RNF168 UDM2 in complex with Lys63-linked diubiquitin
Descriptor: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase RNF168, Ubiquitin-40S ribosomal protein S27a
Authors:Takahashi, T.S, Sato, Y, Fukai, S.
Deposit date:2017-04-27
Release date:2018-03-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168.
Nat Commun, 9, 2018
3B2E
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BU of 3b2e by Molmil
Crystal structure of S. cerevisiae Get3 in the open conformation in complex with Get1 cytosolic domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPase GET3, Golgi to ER traffic protein 1
Authors:Kubota, K, Yamagata, A, Fukai, S.
Deposit date:2011-07-30
Release date:2012-06-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Get1 stabilizes an open dimer conformation of get3 ATPase by binding two distinct interfaces
J.Mol.Biol., 422, 2012
5Y32
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BU of 5y32 by Molmil
Crystal structure of PTP delta Ig1-Ig2 in complex with IL1RAPL1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yamagata, A, Fukai, S.
Deposit date:2017-07-27
Release date:2017-08-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015

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PDB entries from 2024-10-16

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