6WGV
| Mycobacterium tuberculosis pduO-type ATP:cobalamin adenosyltransferase bound to adenosylcobalamin and PPPi | Descriptor: | 5'-DEOXYADENOSINE, COBALAMIN, Corrinoid adenosyltransferase, ... | Authors: | Mascarenhas, R.N, Ruetz, M, Koutmos, M, Banerjee, R. | Deposit date: | 2020-04-06 | Release date: | 2021-01-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.151 Å) | Cite: | Mobile loop dynamics in adenosyltransferase control binding and reactivity of coenzyme B 12 . Proc.Natl.Acad.Sci.USA, 117, 2020
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5UOS
| Crystal Structure of CblC (MMACHC) (1-238), a human B12 processing enzyme, complexed with an Antivitamin B12 | Descriptor: | 1-ethynyl-2,4-difluorobenzene, 2-PHENYLAMINO-ETHANESULFONIC ACID, COBALAMIN, ... | Authors: | Shanmuganathan, A, Karasik, A, Ruetz, M, Banerjee, R, Krautler, B, Koutmos, M. | Deposit date: | 2017-02-01 | Release date: | 2017-06-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Antivitamin B12 Inhibition of the Human B12 -Processing Enzyme CblC: Crystal Structure of an Inactive Ternary Complex with Glutathione as the Cosubstrate. Angew. Chem. Int. Ed. Engl., 56, 2017
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6D5K
| Structure of Human ATP:Cobalamin Adenosyltransferase bound to ATP, and Adenosylcobalamin | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-DEOXYADENOSINE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Dodge, G.J, Campanello, G, Smith, J.L, Banerjee, R. | Deposit date: | 2018-04-19 | Release date: | 2018-10-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Sacrificial Cobalt-Carbon Bond Homolysis in Coenzyme B12as a Cofactor Conservation Strategy. J. Am. Chem. Soc., 140, 2018
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8GO9
| Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human Atypical chemokine receptor 2, ACKR2 (D6R) | Descriptor: | Atypical chemokine receptor 2, Beta-arrestin-2, Fab30 Heavy Chain, ... | Authors: | Maharana, J, Sarma, P, Yadav, M.K, Banerjee, R, Shukla, A.K. | Deposit date: | 2022-08-24 | Release date: | 2023-12-27 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Molecular insights into atypical modes of beta-arrestin interaction with seven transmembrane receptors. Science, 383, 2024
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8I9L
| Structure of C3a-C3aR-Go complex (Composite map) | Descriptor: | Antibody fragment - ScFv16, C3a anaphylatoxin, C3a anaphylatoxin chemotactic receptor, ... | Authors: | Yadav, M.K, Yadav, R, Maharana, J, Sarma, P, Banerjee, R, Shukla, A.K, Gati, C. | Deposit date: | 2023-02-07 | Release date: | 2023-10-18 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023
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8I95
| Structure of EP54-C3aR-Go complex | Descriptor: | Antibody fragment - ScFv16, C3a anaphylatoxin chemotactic receptor, EP54 ligand, ... | Authors: | Yadav, M.K, Yadav, R, Maharana, J, Sarma, P, Banerjee, R, Shukla, A.K, Gati, C. | Deposit date: | 2023-02-06 | Release date: | 2023-10-18 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023
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8I97
| Structure of Apo-C3aR-Go complex (Glacios) | Descriptor: | Antibody fragment - ScFv16, C3a anaphylatoxin chemotactic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Yadav, M.K, Yadav, R, Maharana, J, Sarma, P, Banerjee, R, Shukla, A.K, Gati, C. | Deposit date: | 2023-02-06 | Release date: | 2023-10-18 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023
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8I9A
| Structure of EP54-C3aR-Gq complex | Descriptor: | Antibody fragment - ScFv16, C3a anaphylatoxin chemotactic receptor, EP54 ligand, ... | Authors: | Yadav, M.K, Yadav, R, Maharana, J, Sarma, P, Banerjee, R, Shukla, A.K, Gati, C. | Deposit date: | 2023-02-06 | Release date: | 2023-10-18 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023
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8I9S
| Structure of Apo-C3aR-Go complex (Titan) | Descriptor: | Antibody fragment - ScFv16, C3a anaphylatoxin chemotactic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Yadav, M.K, Yadav, R, Maharana, J, Sarma, P, Banerjee, R, Shukla, A.K, Gati, C. | Deposit date: | 2023-02-07 | Release date: | 2023-10-18 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023
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8IA2
| Structure of C5a bound human C5aR1 in complex with Go (Composite map) | Descriptor: | Antibody fragment - ScFv16, C5a anaphylatoxin, C5a anaphylatoxin chemotactic receptor 1, ... | Authors: | Yadav, M.K, Yadav, R, Maharana, J, Banerjee, R, Shukla, A.K, Gati, C. | Deposit date: | 2023-02-07 | Release date: | 2023-10-18 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023
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8J6D
| Structure of EP141-C3aR-Go complex | Descriptor: | Antibody fragment - ScFv16, C3a anaphylatoxin chemotactic receptor, EP141 peptide agonist, ... | Authors: | Yadav, M.K, Yadav, R, Maharana, J, Sarma, P, Banerjee, R, Shukla, A.K, Gati, C. | Deposit date: | 2023-04-25 | Release date: | 2023-10-18 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023
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8JZZ
| Structure of human C5a-desArg bound human C5aR1 in complex with Go | Descriptor: | Antibody fragment ScFv16, C5a anaphylatoxin, C5a anaphylatoxin chemotactic receptor 1, ... | Authors: | Yadav, M.K, Yadav, R, Maharana, J, Sarma, P, Banerjee, R, Shukla, A.K, Gati, C. | Deposit date: | 2023-07-06 | Release date: | 2023-10-18 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.31 Å) | Cite: | Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186, 2023
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4LRQ
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4LC1
| MeaB, A Bacterial Homolog of MMAA, Bound to GDP and crystallized in the presence of GDP and [AlF4]- | Descriptor: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, Methylmalonyl-CoA mutase accessory protein | Authors: | Koutmos, M, Padovani, D, Lofgren, M, Banerjee, R. | Deposit date: | 2013-06-21 | Release date: | 2013-09-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Autoinhibition and Signaling by the Switch II Motif in the G-protein Chaperone of a Radical B12 Enzyme. J.Biol.Chem., 288, 2013
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6BEV
| Human Single Domain Sulfurtranferase TSTD1 | Descriptor: | Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1 | Authors: | Motl, N, Akey, D.L, Smith, J.L, Banerjee, R. | Deposit date: | 2017-10-25 | Release date: | 2018-01-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.043 Å) | Cite: | Thiosulfate sulfurtransferase-like domain-containing 1 protein interacts with thioredoxin. J. Biol. Chem., 293, 2018
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5UCU
| STRUCTURAL AND MECHANISTIC INSIGHTS INTO HEMOGLOBIN-CATALYZED HYDROGEN SULFIDE OXIDATION AND THE FATE OF POLYSULFIDE PRODUCTS | Descriptor: | HYDROSULFURIC ACID, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | Authors: | Vitvitsky, V, Yadav, P.K, An, S, Seravalli, J, Cho, U.-S, Banerjee, R. | Deposit date: | 2016-12-22 | Release date: | 2017-03-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.797 Å) | Cite: | Structural and Mechanistic Insights into Hemoglobin-catalyzed Hydrogen Sulfide Oxidation and the Fate of Polysulfide Products. J. Biol. Chem., 292, 2017
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5UJC
| Crystal structure of a C.elegans B12-trafficking protein CblC, a human MMACHC homologue | Descriptor: | CO-METHYLCOBALAMIN, D(-)-TARTARIC ACID, GLYCEROL, ... | Authors: | Li, Z, Shanmuganathan, A, Ruetz, M, Yamada, K, Lesniak, N.A, Krautler, B, Brunold, T.C, Banerjee, R, Koutmos, M. | Deposit date: | 2017-01-17 | Release date: | 2017-05-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Coordination chemistry controls the thiol oxidase activity of the B12-trafficking protein CblC. J. Biol. Chem., 292, 2017
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6D5X
| Structure of Human ATP:Cobalamin Adenosyltransferase bound to ATP, Adenosylcobalamin, and Triphosphate | Descriptor: | 5'-DEOXYADENOSINE, ADENOSINE-5'-TRIPHOSPHATE, COBALAMIN, ... | Authors: | Dodge, G.J, Campanello, G, Smith, J.L, Banerjee, R. | Deposit date: | 2018-04-19 | Release date: | 2018-10-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Sacrificial Cobalt-Carbon Bond Homolysis in Coenzyme B12as a Cofactor Conservation Strategy. J. Am. Chem. Soc., 140, 2018
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5VE5
| Crystal structure of persulfide dioxygenase rhodanese fusion protein with rhodanese domain inactivating mutation (C314S) from Burkholderia phytofirmans in complex with glutathione | Descriptor: | BpPRF, CHLORIDE ION, FE (III) ION, ... | Authors: | Motl, N, Skiba, M.A, Smith, J.L, Banerjee, R. | Deposit date: | 2017-04-03 | Release date: | 2017-07-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural and biochemical analyses indicate that a bacterial persulfide dioxygenase-rhodanese fusion protein functions in sulfur assimilation. J. Biol. Chem., 292, 2017
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5VE4
| Crystal structure of persulfide dioxygenase-rhodanese fusion protein with rhodanese domain inactivating mutation (C314S) from Burkholderia phytofirmans | Descriptor: | BpPRF, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Motl, N, Skiba, M.A, Smith, J.L, Banerjee, R. | Deposit date: | 2017-04-03 | Release date: | 2017-07-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural and biochemical analyses indicate that a bacterial persulfide dioxygenase-rhodanese fusion protein functions in sulfur assimilation. J. Biol. Chem., 292, 2017
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3SBZ
| Crystal Structure of Apo-MMACHC (1-244), a human B12 processing enzyme | Descriptor: | GLYCEROL, MALONATE ION, Methylmalonic aciduria and homocystinuria type C protein | Authors: | Koutmos, M, Gherasim, C, Smith, J.L, Banerjee, R. | Deposit date: | 2011-06-06 | Release date: | 2011-06-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of multifunctionality in a vitamin B12-processing enzyme. J.Biol.Chem., 286, 2011
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3SC0
| Crystal Structure of MMACHC (1-238), a human B12 processing enzyme, complexed with MethylCobalamin | Descriptor: | CO-METHYLCOBALAMIN, Methylmalonic aciduria and homocystinuria type C protein | Authors: | Koutmos, M, Gherasim, C, Smith, J.L, Banerjee, R. | Deposit date: | 2011-06-06 | Release date: | 2011-06-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis of multifunctionality in a vitamin B12-processing enzyme. J.Biol.Chem., 286, 2011
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3SBY
| Crystal Structure of SeMet-Substituted Apo-MMACHC (1-244), a human B12 processing enzyme | Descriptor: | Methylmalonic aciduria and homocystinuria type C protein | Authors: | Koutmos, M, Gherasim, C, Smith, J.L, Banerjee, R. | Deposit date: | 2011-06-06 | Release date: | 2011-06-22 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Structural basis of multifunctionality in a vitamin B12-processing enzyme. J.Biol.Chem., 286, 2011
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2QM8
| MeaB, A Bacterial Homolog of MMAA, in the Nucleotide Free Form | Descriptor: | GTPase/ATPase, PHOSPHATE ION | Authors: | Hubbard, P.A, Padovani, D, Labunska, T, Mahlstedt, S.A, Banerjee, R, Drennan, C.L. | Deposit date: | 2007-07-14 | Release date: | 2007-08-28 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure and mutagenesis of the metallochaperone MeaB: insight into the causes of methylmalonic aciduria. J.Biol.Chem., 282, 2007
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2QM7
| MeaB, A Bacterial Homolog of MMAA, Bound to GDP | Descriptor: | GTPase/ATPase, GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION | Authors: | Hubbard, P.A, Padovani, D, Labunska, T, Mahlstedt, S.A, Banerjee, R, Drennan, C.L. | Deposit date: | 2007-07-14 | Release date: | 2007-08-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure and mutagenesis of the metallochaperone MeaB: insight into the causes of methylmalonic aciduria. J.Biol.Chem., 282, 2007
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