8I97

Structure of Apo-C3aR-Go complex (Glacios)

Summary for 8I97

Entry DOI	10.2210/pdb8i97/pdb
EMDB information	35259
Descriptor	C3a anaphylatoxin chemotactic receptor, Guanine nucleotide-binding protein G(o) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (5 entities in total)
Functional Keywords	gpcr, g protein, signaling protein-immune system complex, signaling protein/immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	160864.05
Authors	Yadav, M.K.,Yadav, R.,Maharana, J.,Sarma, P.,Banerjee, R.,Shukla, A.K.,Gati, C. (deposition date: 2023-02-06, release date: 2023-10-18, Last modification date: 2023-11-08)
Primary citation	Yadav, M.K.,Maharana, J.,Yadav, R.,Saha, S.,Sarma, P.,Soni, C.,Singh, V.,Saha, S.,Ganguly, M.,Li, X.X.,Mohapatra, S.,Mishra, S.,Khant, H.A.,Chami, M.,Woodruff, T.M.,Banerjee, R.,Shukla, A.K.,Gati, C. Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell, 186:4956-4973.e21, 2023 Cited by PubMed: 37852260 DOI: 10.1016/j.cell.2023.09.020 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.19 Å)

Structure validation