5IRO
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5IS7
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![BU of 5is7 by Molmil](/molmil-images/mine/5is7) | Crystal structure of mouse CARM1 in complex with decarboxylated SAH | Descriptor: | 1,2-ETHANEDIOL, 5'-S-(3-aminopropyl)-5'-thioadenosine, DI(HYDROXYETHYL)ETHER, ... | Authors: | Cura, V, Marechal, N, Mailliot, J, Troffer-Charlier, N, Hassenboehler, P, Wurtz, J.M, Bonnefond, L, Cavarelli, J. | Deposit date: | 2016-03-15 | Release date: | 2017-03-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Crystal structure of mouse CARM1 in complex with decarboxylated SAH To Be Published
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5KBN
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![BU of 5kbn by Molmil](/molmil-images/mine/5kbn) | The crystal structure of fluoride channel Fluc Ec2 F80I Mutant | Descriptor: | DECYL-BETA-D-MALTOPYRANOSIDE, FLUORIDE ION, Putative fluoride ion transporter CrcB, ... | Authors: | Last, N.B, Kolmakova-Partensky, L, Shane, T, Miller, C. | Deposit date: | 2016-06-03 | Release date: | 2016-08-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Mechanistic signs of double-barreled structure in a fluoride ion channel. Elife, 5, 2016
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4YDU
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![BU of 4ydu by Molmil](/molmil-images/mine/4ydu) | Crystal structure of E. coli YgjD-YeaZ heterodimer in complex with ADP | Descriptor: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, FE (III) ION, ... | Authors: | Zhang, W, Collinet, B, Perrochia, L, Durand, D, Van Tilbeurgh, H. | Deposit date: | 2015-02-23 | Release date: | 2015-03-04 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | The ATP-mediated formation of the YgjD-YeaZ-YjeE complex is required for the biosynthesis of tRNA t6A in Escherichia coli. Nucleic Acids Res., 43, 2015
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4U1W
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![BU of 4u1w by Molmil](/molmil-images/mine/4u1w) | Full length GluA2-kainate-(R,R)-2b complex crystal form A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2, ... | Authors: | Chen, L, Gouaux, E. | Deposit date: | 2014-07-16 | Release date: | 2014-08-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States. Cell, 158, 2014
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4YG3
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8OQY
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![BU of 8oqy by Molmil](/molmil-images/mine/8oqy) | Structure of apo form of human gamma-secretase PSEN1 APH-1B isoform reconstituted into lipid nanodisc | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Odorcic, I, Chavez Gutierrez, L, Efremov, R.G. | Deposit date: | 2023-04-12 | Release date: | 2024-04-24 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Apo and A beta 46-bound gamma-secretase structures provide insights into amyloid-beta processing by the APH-1B isoform. Nat Commun, 15, 2024
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8OQZ
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![BU of 8oqz by Molmil](/molmil-images/mine/8oqz) | Structure of human gamma-secretase PSEN1 APH-1B isoform reconstituted into lipid nanodisc in complex with Ab46 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Odorcic, I, Chavez Gutierrez, L, Efremov, R.G. | Deposit date: | 2023-04-12 | Release date: | 2024-04-24 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Apo and A beta 46-bound gamma-secretase structures provide insights into amyloid-beta processing by the APH-1B isoform. Nat Commun, 15, 2024
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5JTI
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2ATQ
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![BU of 2atq by Molmil](/molmil-images/mine/2atq) | RB69 single-stranded DNA binding protein-DNA polymerase fusion | Descriptor: | DNA polymerase, GUANOSINE-5'-DIPHOSPHATE, ZINC ION, ... | Authors: | Sun, S, Geng, L, Shamoo, Y. | Deposit date: | 2005-08-25 | Release date: | 2006-05-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure and enzymatic properties of a chimeric bacteriophage RB69 DNA polymerase and single-stranded DNA binding protein with increased processivity. Proteins, 65, 2006
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2AGX
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![BU of 2agx by Molmil](/molmil-images/mine/2agx) | Crystal structure of the Schiff base intermediate in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with tryptamine. P212121 form | Descriptor: | 2-(1H-INDOL-3-YL)ETHANIMINE, Aromatic amine dehydrogenase | Authors: | Masgrau, L, Roujeinikova, A, Johannissen, L.O, Hothi, P, Basran, J, Ranaghan, K.E, Mulholland, A.J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. | Deposit date: | 2005-07-27 | Release date: | 2006-04-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Atomic description of an enzyme reaction dominated by proton tunneling Science, 312, 2006
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4RV1
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![BU of 4rv1 by Molmil](/molmil-images/mine/4rv1) | Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium (NESG) Target OR497. | Descriptor: | ACETATE ION, Engineered Protein OR497 | Authors: | Vorobiev, S, Parmeggiani, F, Seetharaman, J, Xiao, R, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2014-11-24 | Release date: | 2014-12-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.573 Å) | Cite: | Crystal Structure of Engineered Protein OR497. To be Published
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4YOM
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![BU of 4yom by Molmil](/molmil-images/mine/4yom) | Structure of SAD kinase | Descriptor: | 1,2-ETHANEDIOL, Serine/threonine-protein kinase BRSK2 | Authors: | Wu, J.X, Wang, J, Chen, L, Wang, Z.X, Wu, J.W. | Deposit date: | 2015-03-12 | Release date: | 2015-12-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structural insight into the mechanism of synergistic autoinhibition of SAD kinases Nat Commun, 6, 2015
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2B2D
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![BU of 2b2d by Molmil](/molmil-images/mine/2b2d) | RNA stemloop operator from bacteriophage QBETA complexed with an N87S,E89K mutant MS2 capsid | Descriptor: | 5'-R(*AP*UP*GP*CP*AP*UP*GP*UP*CP*UP*AP*AP*GP*AP*CP*AP*GP*CP*AP*U)-3', Coat protein | Authors: | Horn, W.T, Tars, K, Grahn, E, Helgstrand, C, Baron, A.J, Lago, H, Adams, C.J, Peabody, D.S, Phillips, S.E.V, Stonehouse, N.J, Liljas, L, Stockley, P.G. | Deposit date: | 2005-09-19 | Release date: | 2006-05-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis of RNA binding discrimination between bacteriophages Qbeta and MS2 Structure, 14, 2006
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4S0H
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![BU of 4s0h by Molmil](/molmil-images/mine/4s0h) | TBX5 DB, NKX2.5 HD, ANF DNA Complex | Descriptor: | 5'-D(*CP*CP*AP*CP*TP*TP*CP*AP*AP*AP*GP*GP*TP*GP*TP*GP*AP*GP*A)-3', 5'-D(*TP*CP*TP*CP*AP*CP*AP*CP*CP*TP*TP*TP*GP*AP*AP*GP*TP*GP*G)-3', Homeobox protein Nkx-2.5, ... | Authors: | Pradhan, L. | Deposit date: | 2014-12-31 | Release date: | 2015-12-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.817 Å) | Cite: | Intermolecular Interactions of Cardiac Transcription Factors NKX2.5 and TBX5. Biochemistry, 55, 2016
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5K1H
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![BU of 5k1h by Molmil](/molmil-images/mine/5k1h) | eIF3b relocated to the intersubunit face to interact with eIF1 and below the eIF2 ternary-complex. from the structure of a partial yeast 48S preinitiation complex in closed conformation. | Descriptor: | Eukaryotic translation initiation factor 3 subunit B, eIF3a C-terminal tail | Authors: | Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y. | Deposit date: | 2016-05-18 | Release date: | 2016-07-13 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition. Mol.Cell, 63, 2016
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4YSB
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![BU of 4ysb by Molmil](/molmil-images/mine/4ysb) | Crystal structure of ETHE1 from Myxococcus xanthus | Descriptor: | FE (III) ION, Metallo-beta-lactamase family protein | Authors: | Sattler, S.A, Wang, X, DeHan, P.J, Xun, L, Kang, C. | Deposit date: | 2015-03-17 | Release date: | 2015-06-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5015 Å) | Cite: | Characterizations of Two Bacterial Persulfide Dioxygenases of the Metallo-beta-lactamase Superfamily. J.Biol.Chem., 290, 2015
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4YSK
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![BU of 4ysk by Molmil](/molmil-images/mine/4ysk) | Crystal structure of apo-form SdoA from Pseudomonas putida | Descriptor: | Beta-lactamase domain protein, FE (III) ION | Authors: | Sattler, S.A, Wang, X, DeHan, P.J, Xun, L, Kang, C. | Deposit date: | 2015-03-17 | Release date: | 2015-06-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.466 Å) | Cite: | Characterizations of Two Bacterial Persulfide Dioxygenases of the Metallo-beta-lactamase Superfamily. J.Biol.Chem., 290, 2015
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2B3T
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![BU of 2b3t by Molmil](/molmil-images/mine/2b3t) | Structure of complex between E. coli translation termination factor RF1 and the PrmC methyltransferase | Descriptor: | Peptide chain release factor 1, Protein methyltransferase hemK, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Graille, M, Heurgue-Hamard, V, Champ, S, Mora, L, Scrima, N, Ulryck, N, van Tilbeurgh, H, Buckingham, R.H. | Deposit date: | 2005-09-21 | Release date: | 2006-01-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Molecular basis for bacterial class I release factor methylation by PrmC Mol.Cell, 20, 2005
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4TNM
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2PSO
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![BU of 2pso by Molmil](/molmil-images/mine/2pso) | Human StarD13 (DLC2) lipid transfer and protein localization domain | Descriptor: | StAR-related lipid transfer protein 13 | Authors: | Lehtio, L, Busam, R, Arrowsmith, C.H, Berglund, H, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Ogg, D, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van den Berg, S, Weigelt, J, Welin, M, Persson, C, Structural Genomics Consortium (SGC) | Deposit date: | 2007-05-07 | Release date: | 2007-05-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Comparative structural analysis of lipid binding START domains. Plos One, 6, 2011
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4RV4
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![BU of 4rv4 by Molmil](/molmil-images/mine/4rv4) | 2.65 Angstrom Resolution Crystal Structure of an orotate phosphoribosyltransferase from Bacillus anthracis str. 'Ames Ancestor' in complex with 5-phospho-alpha-D-ribosyl diphosphate (PRPP) | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, DI(HYDROXYETHYL)ETHER, Orotate phosphoribosyltransferase | Authors: | Halavaty, A.S, Minasov, G, Shuvalova, L, Winsor, J, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2014-11-24 | Release date: | 2014-12-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | 2.65 Angstrom resolution crystal structure of an orotate phosphoribosyltransferase from Bacillus anthracis str. 'Ames Ancestor' in complex with 5-phospho-alpha-D-ribosyl diphosphate (PRPP) To be Published
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2AHB
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![BU of 2ahb by Molmil](/molmil-images/mine/2ahb) | X-ray crystal structure of R46A,R161A mutant of Mycobacterium tuberculosis FabH | Descriptor: | Beta- ketoacyl-ACP synthase III | Authors: | Brown, A.K, Sridharan, S, Kremer, L, Lindenberg, S, Dover, L.G, Sacchettini, J.C, Besra, G.S. | Deposit date: | 2005-07-27 | Release date: | 2005-08-23 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Probing the Mechanism of the Mycobacterium tuberculosis {beta}-Ketoacyl-Acyl Carrier Protein Synthase III mtFabH: FACTORS INFLUENCING CATALYSIS AND SUBSTRATE SPECIFICITY J.Biol.Chem., 280, 2005
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5JTJ
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![BU of 5jtj by Molmil](/molmil-images/mine/5jtj) | USP7CD-CTP in complex with Ubiquitin | Descriptor: | CALCIUM ION, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7,Ubiquitin carboxyl-terminal hydrolase 7 | Authors: | Murray, J.M, Rouge, L. | Deposit date: | 2016-05-09 | Release date: | 2016-08-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.321 Å) | Cite: | Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation. Structure, 24, 2016
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2AHR
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![BU of 2ahr by Molmil](/molmil-images/mine/2ahr) | Crystal Structures of 1-Pyrroline-5-Carboxylate Reductase from Human Pathogen Streptococcus pyogenes | Descriptor: | FORMIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SODIUM ION, ... | Authors: | Nocek, B, Lezondra, L, Holzle, D, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-07-28 | Release date: | 2005-09-13 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal Structures of Delta(1)-Pyrroline-5-carboxylate Reductase from Human Pathogens Neisseria meningitides and Streptococcus pyogenes J.Mol.Biol., 354, 2005
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