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5DAI
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BU of 5dai by Molmil
Proliferating cell nuclear antigen homolog 1 bound to FEN-1 peptide
Descriptor: C-terminus of FEN-1 protein, DNA polymerase sliding clamp 1, SULFATE ION
Authors:Ladner, J.E, Altieri, A.S, Kelman, Z.
Deposit date:2015-08-20
Release date:2016-05-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp.
Nucleic Acids Res., 44, 2016
5DA7
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BU of 5da7 by Molmil
monomeric PCNA bound to a small protein inhibitor
Descriptor: DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen, SULFATE ION, ...
Authors:Ladner, J.E, Altieri, A.S, Kelman, Z.
Deposit date:2015-08-19
Release date:2016-05-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp.
Nucleic Acids Res., 44, 2016
6LHB
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BU of 6lhb by Molmil
The cryo-EM structure of coxsackievirus A16 A-particle
Descriptor: VP1, VP2, VP3
Authors:He, M.Z, Xu, L.F, Zheng, Q.B, Zhu, R, Yin, Z.C, Cheng, T, Li, S.W.
Deposit date:2019-12-07
Release date:2020-02-05
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16.
Cell Host Microbe, 27, 2020
6LHP
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BU of 6lhp by Molmil
The cryo-EM structure of coxsackievirus A16 mature virion in complex with Fab 14B10
Descriptor: SPHINGOSINE, VP1 protein, VP2 protein, ...
Authors:He, M.Z, Xu, L.F, Zheng, Q.B, Zhu, R, Yin, Z.C, Cheng, T, Li, S.W.
Deposit date:2019-12-09
Release date:2020-02-05
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16.
Cell Host Microbe, 27, 2020
7FC0
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BU of 7fc0 by Molmil
Reconstitution of MbnABC complex from Rugamonas rubra ATCC-43154 (GroupIII)
Descriptor: FE (III) ION, Methanobactin biosynthesis cassette protein MbnB, Methanobactin biosynthesis cassette protein MbnC, ...
Authors:Chao, D, Zhaolin, L, Shoujie, L, Li, Z, Dan, Z, Ying, J, Wei, C.
Deposit date:2021-07-13
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.643 Å)
Cite:Crystal structure and catalytic mechanism of the MbnBC holoenzyme required for methanobactin biosynthesis.
Cell Res., 32, 2022
5JQE
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BU of 5jqe by Molmil
Crystal structure of caspase8 tDED
Descriptor: Sugar ABC transporter substrate-binding protein,Caspase-8 chimera
Authors:Fu, T, Li, Y, Lu, A, Wu, H.
Deposit date:2016-05-04
Release date:2016-10-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.157 Å)
Cite:Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.
Mol. Cell, 64, 2016
6LB0
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BU of 6lb0 by Molmil
The cryo-EM structure of HEV VLP in complex with Fab 8C11
Descriptor: Protein ORF2
Authors:Zheng, Q, He, M, Li, S.
Deposit date:2019-11-13
Release date:2019-12-04
Last modified:2025-06-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Viral neutralization by antibody-imposed physical disruption.
Proc.Natl.Acad.Sci.USA, 2019
6LHO
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BU of 6lho by Molmil
The cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab 18A7
Descriptor: VP1 protein, VP2 protein, VP3 protein
Authors:He, M.Z, Xu, L.F, Zheng, Q.B, Zhu, R, Yin, Z.C, Cheng, T, Li, S.W.
Deposit date:2019-12-09
Release date:2020-02-05
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16.
Cell Host Microbe, 27, 2020
6LHK
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BU of 6lhk by Molmil
The cryo-EM structure of coxsackievirus A16 mature virion in complex with Fab 18A7
Descriptor: SPHINGOSINE, VP1 protein, VP2 protein, ...
Authors:He, M.Z, Xu, L.F, Zheng, Q.B, Zhu, R, Yin, Z.C, Cheng, T, Li, S.W.
Deposit date:2019-12-09
Release date:2020-02-05
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16.
Cell Host Microbe, 27, 2020
6LHA
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BU of 6lha by Molmil
The cryo-EM structure of coxsackievirus A16 mature virion
Descriptor: SPHINGOSINE, VP1 protein, VP2 protein, ...
Authors:He, M.Z, Xu, L.F, Zheng, Q.B, Zhu, R, Yin, Z.C, Cheng, T, Li, S.W.
Deposit date:2019-12-07
Release date:2020-02-05
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16.
Cell Host Microbe, 27, 2020
6LHQ
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BU of 6lhq by Molmil
The cryo-EM structure of coxsackievirus A16 mature virion in complex with Fab NA9D7
Descriptor: SPHINGOSINE, VP1 protein, VP2 protein, ...
Authors:He, M.Z, Xu, L.F, Zheng, Q.B, Zhu, R, Yin, Z.C, Cheng, T, Li, S.W.
Deposit date:2019-12-09
Release date:2020-02-05
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16.
Cell Host Microbe, 27, 2020
6LHT
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BU of 6lht by Molmil
Localized reconstruction of coxsackievirus A16 mature virion in complex with Fab 18A7
Descriptor: SPHINGOSINE, VP1 protein, heavy chain variable region of Fab 18A7, ...
Authors:He, M.Z, Xu, L.F, Zheng, Q.B, Zhu, R, Yin, Z.C, Cheng, T, Li, S.W.
Deposit date:2019-12-10
Release date:2020-02-05
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16.
Cell Host Microbe, 27, 2020
6L5M
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BU of 6l5m by Molmil
Crystal structure of human DEAD-box RNA helicase DDX21 in complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, Nucleolar RNA helicase 2
Authors:Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X.
Deposit date:2019-10-24
Release date:2020-06-17
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Adv Sci, 7, 2020
6L5L
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BU of 6l5l by Molmil
Crystal structure of human DEAD-box RNA helicase DDX21 at apo state
Descriptor: MAGNESIUM ION, Nucleolar RNA helicase 2
Authors:Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X.
Deposit date:2019-10-24
Release date:2020-06-17
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Adv Sci, 7, 2020
9L9W
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BU of 9l9w by Molmil
Structure of SPARTA in complex with guide DNA and a 19nt target DNA
Descriptor: DNA (5'-D(*T*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*AP*T)-3'), DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), MAGNESIUM ION, ...
Authors:Hu, R, Guo, C, Liu, X, Chen, J, Liu, L.
Deposit date:2024-12-31
Release date:2025-03-12
Method:X-RAY DIFFRACTION (5.87 Å)
Cite:Structural basis of ssDNA-guided NADase activation of prokaryotic SPARTA system.
Nucleic Acids Res., 53, 2025
9L9X
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BU of 9l9x by Molmil
Structure of SPARTA in complex with guide DNA and a 20nt target DNA
Descriptor: DNA (5'-D(*TP*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*AP*T)-3'), DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'), MAGNESIUM ION, ...
Authors:Hu, R, Guo, C, Liu, X, Chen, J, Liu, L.
Deposit date:2024-12-31
Release date:2025-03-12
Method:X-RAY DIFFRACTION (6.7 Å)
Cite:Structural basis of ssDNA-guided NADase activation of prokaryotic SPARTA system.
Nucleic Acids Res., 53, 2025
6L5N
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BU of 6l5n by Molmil
Crystal structure of human DEAD-box RNA helicase DDX21 at post-unwound state
Descriptor: MAGNESIUM ION, Nucleolar RNA helicase 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X.
Deposit date:2019-10-24
Release date:2020-06-17
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.242 Å)
Cite:Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Adv Sci, 7, 2020
6L5O
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BU of 6l5o by Molmil
Crystal structure of human DEAD-box RNA helicase DDX21 at post-hydrolysis state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X.
Deposit date:2019-10-24
Release date:2020-06-17
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.
Adv Sci, 7, 2020
8HRD
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BU of 8hrd by Molmil
Crystal structure of the receptor binding domain of SARS-CoV-2 Delta variant in complex with IMCAS74 Fab and W14 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IMCAS74 Fab heavy chain, IMCAS74 Fab light chain, ...
Authors:Zhao, R.C, Wu, L.L, Han, P.
Deposit date:2022-12-15
Release date:2023-12-20
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
1KGF
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BU of 1kgf by Molmil
STRUCTURE OF BETA-LACTAMASE ASN 170 GLN MUTANT
Descriptor: BETA-LACTAMASE
Authors:Chen, C.C.H, Zawadzke, L.E, Herzberg, O.
Deposit date:1996-10-17
Release date:1997-03-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Elimination of the hydrolytic water molecule in a class A beta-lactamase mutant: crystal structure and kinetics.
Biochemistry, 35, 1996
1KGE
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BU of 1kge by Molmil
STRUCTURE OF BETA-LACTAMASE ASN 170 MET MUTANT
Descriptor: BETA-LACTAMASE
Authors:Chen, C.C.H, Zawadzke, L.E, Herzberg, O.
Deposit date:1996-10-17
Release date:1997-04-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Elimination of the hydrolytic water molecule in a class A beta-lactamase mutant: crystal structure and kinetics.
Biochemistry, 35, 1996
9KMB
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BU of 9kmb by Molmil
Crystal structure of human glutaminyl cyclase in complex with N-(2-(1H-imidazol-5-yl)ethyl)-4-methoxybenzenesulfonamide
Descriptor: Glutaminyl-peptide cyclotransferase, ZINC ION, ~{N}-[2-(1~{H}-imidazol-5-yl)ethyl]-4-methoxy-benzenesulfonamide
Authors:Li, G.-B, Wu, J.-W, Ning, X.-L.
Deposit date:2024-11-15
Release date:2025-06-25
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Deciphering Glutaminyl Cyclase Catalytic Pathways Enables Recognition of Anchor Pharmacophores for Inhibitor Discovery.
J.Chem.Inf.Model., 65, 2025
5XS7
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BU of 5xs7 by Molmil
Structure of Coxsackievirus A6 (CVA6) virus A-particle in complex with the neutralizing antibody fragment 1D5
Descriptor: Genome polyprotein, Heavy chain of Fab 1D5, Light chain of Fab 1D5
Authors:Zheng, Q.B, He, M.Z, Xu, L.F, Yu, H, Li, S.W, Cheng, T.
Deposit date:2017-06-12
Release date:2017-09-27
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody
Nat Commun, 8, 2017
5XS4
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BU of 5xs4 by Molmil
Structure of Coxsackievirus A6 (CVA6) virus A-particle
Descriptor: Genome polyprotein
Authors:Zheng, Q.B, He, M.Z, Xu, L.F, Yu, H, Li, S.W, Cheng, T.
Deposit date:2017-06-12
Release date:2017-09-27
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody
Nat Commun, 8, 2017
6ZAY
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BU of 6zay by Molmil
Crystal structure of Atg16L in complex with GDP-bound Rab33B
Descriptor: 1,2-ETHANEDIOL, Autophagy-related protein 16-1, DI(HYDROXYETHYL)ETHER, ...
Authors:Pantoom, S, Wu, Y.W.
Deposit date:2020-06-06
Release date:2020-09-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:RAB33B recruits the ATG16L1 complex to the phagophore via a noncanonical RAB binding protein.
Autophagy, 17, 2021

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