1RAG
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![BU of 1rag by Molmil](/molmil-images/mine/1rag) | CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY | Descriptor: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... | Authors: | Kosman, R.P, Gouaux, J.E, Lipscomb, W.N. | Deposit date: | 1992-08-14 | Release date: | 1994-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity. Proteins, 15, 1993
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4PQ6
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![BU of 4pq6 by Molmil](/molmil-images/mine/4pq6) | |
4PQB
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![BU of 4pqb by Molmil](/molmil-images/mine/4pqb) | |
1RAD
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![BU of 1rad by Molmil](/molmil-images/mine/1rad) | CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY | Descriptor: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... | Authors: | Kosman, R.P, Gouaux, J.E, Lipscomb, W.N. | Deposit date: | 1992-08-14 | Release date: | 1994-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity. Proteins, 15, 1993
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1RAB
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![BU of 1rab by Molmil](/molmil-images/mine/1rab) | CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY | Descriptor: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... | Authors: | Kosman, R.P, Gouaux, J.E, Lipscomb, W.N. | Deposit date: | 1992-08-14 | Release date: | 1994-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity. Proteins, 15, 1993
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1RAA
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![BU of 1raa by Molmil](/molmil-images/mine/1raa) | CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY | Descriptor: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... | Authors: | Kosman, R.P, Gouaux, J.E, Lipscomb, W.N. | Deposit date: | 1992-08-14 | Release date: | 1994-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity. Proteins, 15, 1993
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1RAI
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![BU of 1rai by Molmil](/molmil-images/mine/1rai) | CRYSTAL STRUCTURE OF CTP-LIGATED T STATE ASPARTATE TRANSCARBAMOYLASE AT 2.5 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ATCASE MUTANTS AND THE MECHANISM OF NEGATIVE COOPERATIVITY | Descriptor: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... | Authors: | Kosman, R.P, Gouaux, J.E, Lipscomb, W.N. | Deposit date: | 1992-08-14 | Release date: | 1994-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 A resolution: implications for ATCase mutants and the mechanism of negative cooperativity. Proteins, 15, 1993
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3TBL
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![BU of 3tbl by Molmil](/molmil-images/mine/3tbl) | Structure of Mono-ubiquitinated PCNA: Implications for DNA Polymerase Switching and Okazaki Fragment Maturation | Descriptor: | Proliferating cell nuclear antigen, Ubiquitin | Authors: | Zhang, Z, Lee, M, Lee, E, Zhang, S. | Deposit date: | 2011-08-07 | Release date: | 2012-05-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.903 Å) | Cite: | Structure of monoubiquitinated PCNA: Implications for DNA polymerase switching and Okazaki fragment maturation. Cell Cycle, 11, 2012
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4PQC
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![BU of 4pqc by Molmil](/molmil-images/mine/4pqc) | |
6IX4
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![BU of 6ix4 by Molmil](/molmil-images/mine/6ix4) | Structure of an epoxide hydrolase from Aspergillus usamii E001 (AuEH2) at 1.51 Angstroms resolution | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Hu, D, Hu, B.C, Hou, X.D, Wu, L, Rao, Y.J, Wu, M.C. | Deposit date: | 2018-12-09 | Release date: | 2019-12-11 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.511 Å) | Cite: | Nearly perfect kinetic resolution of racemic o-nitrostyrene oxide by AuEH2, a microsomal epoxide hydrolase from Aspergillus usamii, with high enantio- and regio-selectivity. Int.J.Biol.Macromol., 169, 2021
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8J5J
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![BU of 8j5j by Molmil](/molmil-images/mine/8j5j) | The crystal structure of bat coronavirus RsYN04 RBD bound to the antibody S43 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, nano antibody S43 | Authors: | Zhao, R.C, Niu, S, Han, P, Qi, J.X, Gao, G.F, Wang, Q.H. | Deposit date: | 2023-04-23 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Cross-species recognition of bat coronavirus RsYN04 and cross-reaction of SARS-CoV-2 antibodies against the virus. Zool.Res., 44, 2023
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7V68
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![BU of 7v68 by Molmil](/molmil-images/mine/7v68) | An Agonist and PAM-bound Class A GPCR with Gi protein complex structure | Descriptor: | 3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide, 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Wang, J.J, Wu, L.J, Wu, M, Hua, T, Liu, Z.J, Wang, T. | Deposit date: | 2021-08-20 | Release date: | 2022-05-11 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | The unconventional activation of the muscarinic acetylcholine receptor M4R by diverse ligands. Nat Commun, 13, 2022
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7V6A
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![BU of 7v6a by Molmil](/molmil-images/mine/7v6a) | Cry-EM structure of M4-c110-G protein complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Wang, J.J, Wu, M, Wu, L.J, Hua, T, Liu, Z.J, Wang, T. | Deposit date: | 2021-08-20 | Release date: | 2022-05-11 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | The unconventional activation of the muscarinic acetylcholine receptor M4R by diverse ligands. Nat Commun, 13, 2022
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7V69
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![BU of 7v69 by Molmil](/molmil-images/mine/7v69) | Cryo-EM structure of a class A GPCR-G protein complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Wang, J.J, Wu, M, Wu, L.J, Hua, T, Liu, Z.J, Wang, T. | Deposit date: | 2021-08-20 | Release date: | 2022-05-11 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | The unconventional activation of the muscarinic acetylcholine receptor M4R by diverse ligands. Nat Commun, 13, 2022
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5YAO
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![BU of 5yao by Molmil](/molmil-images/mine/5yao) | The complex structure of SZ529 and expoxid | Descriptor: | (1R,5S)-6-oxabicyclo[3.1.0]hexane, Limonene-1,2-epoxide hydrolase, SODIUM ION | Authors: | Lian, W, Sun, Z.T, Zhou, J.H, Reetz, M.T. | Deposit date: | 2017-09-01 | Release date: | 2018-06-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.611 Å) | Cite: | Structural and Computational Insight into the Catalytic Mechanism of Limonene Epoxide Hydrolase Mutants in Stereoselective Transformations J. Am. Chem. Soc., 140, 2018
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5YDM
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![BU of 5ydm by Molmil](/molmil-images/mine/5ydm) | |
5YDL
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![BU of 5ydl by Molmil](/molmil-images/mine/5ydl) | |
5YDA
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![BU of 5yda by Molmil](/molmil-images/mine/5yda) | |
4Q6I
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![BU of 4q6i by Molmil](/molmil-images/mine/4q6i) | Crystal structure of murine 2D5 Fab, a potent anti-CD4 HIV-1-neutralizing antibody in complex with CD4 | Descriptor: | Heavy chain of murine 2D5 Fab, Light chain of murine 2D5 Fab, T-cell surface glycoprotein CD4 | Authors: | Boyington, J.C, Nabel, G.J, Mascola, J.R. | Deposit date: | 2014-04-22 | Release date: | 2014-07-23 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor. Sci Transl Med, 6, 2014
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4QQX
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![BU of 4qqx by Molmil](/molmil-images/mine/4qqx) | Crystal structure of T. fusca Cas3-ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CRISPR-associated helicase, Cas3 family, ... | Authors: | Ke, A, Huo, Y, Nam, K.H. | Deposit date: | 2014-06-30 | Release date: | 2014-08-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.34 Å) | Cite: | Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation. Nat.Struct.Mol.Biol., 21, 2014
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4RFW
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![BU of 4rfw by Molmil](/molmil-images/mine/4rfw) | Crystal structure of human retinoid X Receptor alpha-ligand binding domain complex with 9cUAB70 and the coactivator peptide GRIP-1 | Descriptor: | (2E,4E,6Z,8E)-3,7-dimethyl-8-(6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ylidene)octa-2,4,6-trienoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha | Authors: | Xia, G, Muccio, D.D, Smith, C.D. | Deposit date: | 2014-09-28 | Release date: | 2015-09-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers. J.Med.Chem., 58, 2015
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4QQW
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![BU of 4qqw by Molmil](/molmil-images/mine/4qqw) | Crystal structure of T. fusca Cas3 | Descriptor: | CRISPR-associated helicase, Cas3 family, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ... | Authors: | Ke, A, Huo, Y, Nam, K.H. | Deposit date: | 2014-06-30 | Release date: | 2014-08-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.664 Å) | Cite: | Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation. Nat.Struct.Mol.Biol., 21, 2014
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4QQZ
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![BU of 4qqz by Molmil](/molmil-images/mine/4qqz) | Crystal structure of T. fusca Cas3-AMPPNP | Descriptor: | CRISPR-associated helicase, Cas3 family, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ... | Authors: | Ke, A, Huo, Y, Nam, K.H. | Deposit date: | 2014-06-30 | Release date: | 2014-08-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.93 Å) | Cite: | Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation. Nat.Struct.Mol.Biol., 21, 2014
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4QQY
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![BU of 4qqy by Molmil](/molmil-images/mine/4qqy) | Crystal structure of T. fusca Cas3-ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CRISPR-associated helicase, Cas3 family, ... | Authors: | Ke, A, Huo, Y, Nam, K.H. | Deposit date: | 2014-06-30 | Release date: | 2014-08-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation. Nat.Struct.Mol.Biol., 21, 2014
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7VUJ
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![BU of 7vuj by Molmil](/molmil-images/mine/7vuj) | Cryo-EM structure of a class A orphan GPCR | Descriptor: | 3-chloranyl-N-[2-oxidanylidene-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide, GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Liu, Z.J, Hua, T, Zhou, Y.L, Wu, L.J. | Deposit date: | 2021-11-02 | Release date: | 2021-12-29 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Molecular insights into ligand recognition and G protein coupling of the neuromodulatory orphan receptor GPR139. Cell Res., 32, 2022
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