3RRU
 
 | | X-ray crystal structure of the VHS domain of human TOM1-like protein, Northeast Structural Genomics Consortium Target HR3050E | | Descriptor: | TOM1L1 protein | | Authors: | Forouhar, F, Lew, S, Seetharaman, J, Wang, H, Ciccosanti, C, Patel, D, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2011-04-30 | | Release date: | 2011-06-08 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | X-ray crystal structure of the VHS domain of human TOM1-like protein, Northeast Structural Genomics Consortium Target HR3050E
To be Published
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3RD4
 | | Crystal structure of PROPEN_03304 from Proteus penneri ATCC 35198 Northeast Structural Genomics Consortium target id PvR55 | | Descriptor: | uncharacterized protein | | Authors: | Seetharaman, J, Min, S, Kuzin, A, Wang, D, Ciccosanti, C, Sahdev, S, Nair, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2011-03-31 | | Release date: | 2011-05-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of PROPEN_03304 from Proteus penneri ATCC 35198 Northeast Structural Genomics Consortium target id PvR55
To be Published
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4G06
 | | Crystal structure of protein SP_0782 (7-79) from Streptococcus pneumoniae complexed with ssDNA. Northeast Structural Genomics Consortium (NESG) target SPR104 | | Descriptor: | DI(HYDROXYETHYL)ETHER, THYMIDINE-5'-MONOPHOSPHATE, Uncharacterized protein | | Authors: | Kuzin, A.P, Su, M, Seetharaman, J, Patel, P, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2012-07-09 | | Release date: | 2012-07-25 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.905 Å) | | Cite: | Northeast Structural Genomics Consortium Target SpR104
To be Published
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4GVW
 | | Three-dimensional structure of the de novo designed serine hydrolase 2bfq_3, Northeast Structural Genomics Consortium (NESG) Target OR248 | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETIC ACID, De novo designed serine hydrolase, ... | | Authors: | Kuzin, A, Lew, S, Seetharaman, J, Rajagopalan, S, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2012-08-31 | | Release date: | 2012-09-12 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.113 Å) | | Cite: | Northeast Structural Genomics Consortium Target OR248
To be Published
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4HG0
 | | Crystal Structure of magnesium and cobalt efflux protein CorC, Northeast Structural Genomics Consortium (NESG) Target ER40 | | Descriptor: | ADENOSINE MONOPHOSPHATE, Magnesium and cobalt efflux protein CorC | | Authors: | Kuzin, A, Neely, H, Seetharaman, J, Patel, P, Xiao, R, Ciccosanti, C, Cooper, B, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2012-10-05 | | Release date: | 2013-02-06 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (3.102 Å) | | Cite: | Northeast Structural Genomics Consortium Target ER40
To be Published
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4HHU
 | | Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR280. | | Descriptor: | 3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL, OR280, TETRAETHYLENE GLYCOL | | Authors: | Vorobiev, S, Lew, S, Lin, Y.-R, Seetharaman, J, Castelllanos, J, Maglaqui, M, Xiao, R, Lee, D, Koga, N, Koga, R, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2012-10-10 | | Release date: | 2012-10-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of Engineered Protein OR280.
To be Published
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4HQD
 | | Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR265. | | Descriptor: | Engineered Protein OR265 | | Authors: | Vorobiev, S, Su, M, Parmeggiani, F, Seetharaman, J, Huang, P.-S, Maglaqui, M, Xiao, R, Lee, D, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2012-10-25 | | Release date: | 2012-11-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.433 Å) | | Cite: | Crystal Structure of Engineered Protein OR265.
To be Published
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4HNU
 | | crystal structure of K442E mutant of S. aureus Pyruvate carboxylase | | Descriptor: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... | | Authors: | Yu, L.P.C, Tong, L. | | Deposit date: | 2012-10-21 | | Release date: | 2013-01-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Characterizing the Importance of the Biotin Carboxylase Domain Dimer for Staphylococcus aureus Pyruvate Carboxylase Catalysis.
Biochemistry, 52, 2013
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4HNV
 | | Crystal structure of R54E mutant of S. aureus Pyruvate carboxylase | | Descriptor: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Yu, L.P.C, Tong, L. | | Deposit date: | 2012-10-21 | | Release date: | 2013-01-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Characterizing the Importance of the Biotin Carboxylase Domain Dimer for Staphylococcus aureus Pyruvate Carboxylase Catalysis.
Biochemistry, 52, 2013
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4GVV
 | | Crystal Structure of de novo design serine hydrolase OSH55.27, Northeast Structural Genomics Consortium (NESG) Target OR246 | | Descriptor: | De novo design serine hydrolase | | Authors: | Kuzin, A, Lew, S, Seetharaman, J, Mao, M, Xiao, R, Kohan, E, Rajagopalan, S, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2012-08-31 | | Release date: | 2012-09-12 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.895 Å) | | Cite: | Northeast Structural Genomics Consortium Target OR246
To be Published
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4H3H
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4INA
 | | Crystal Structure of the Q7MSS8_WOLSU protein from Wolinella succinogenes. Northeast Structural Genomics Consortium Target WsR35 | | Descriptor: | saccharopine dehydrogenase | | Authors: | Vorobiev, S, Su, M, Seetharaman, J, Maglaqui, M, Xiao, R, Kohan, E, Wang, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2013-01-04 | | Release date: | 2013-01-16 | | Last modified: | 2013-11-27 | | Method: | X-RAY DIFFRACTION (2.488 Å) | | Cite: | Crystal Structure of the Q7MSS8_WOLSU protein from Wolinella succinogenes.
To be Published
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4FJ4
 | | Crystal structure of the protein Q9HRE7 complexed with mercury from Halobacterium salinarium at the resolution 2.1A, Northeast Structural Genomics Consortium target HsR50 | | Descriptor: | ETHYL MERCURY ION, SODIUM ION, Uncharacterized protein | | Authors: | Kuzin, A, Chen, Y, Vorobiev, S.M, Seetharaman, J, Janjua, J, Xiao, R, Cunningham, K, Maglaqui, M, Owens, L.A, Wang, H, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2012-06-11 | | Release date: | 2012-08-22 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Northeast Structural Genomics Consortium Target HsR50
To be Published
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4GIF
 | | C-terminal coiled-coil domain of transient receptor potential channel TRPP3 (PKD2L1, Polycystin-L) | | Descriptor: | Polycystic kidney disease 2-like 1 protein | | Authors: | Yu, Y, Ulbrich, M.H, Li, M.-H, Dobbins, S, Zhang, W.K, Tong, L, Isacoff, E.Y, Yang, J. | | Deposit date: | 2012-08-08 | | Release date: | 2012-12-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Molecular mechanism of the assembly of an acid-sensing receptor ion channel complex.
Nat Commun, 3, 2012
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4GPS
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4GPU
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4IZC
 | | Crystal structure of DmdD E121A in complex with MTA-CoA | | Descriptor: | Enoyl-CoA hydratase/isomerase family protein, methylthioacryloyl-CoA | | Authors: | Tan, D, Tong, L. | | Deposit date: | 2013-01-29 | | Release date: | 2013-06-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structure of DmdD, a Crotonase Superfamily Enzyme That Catalyzes the Hydration and Hydrolysis of Methylthioacryloyl-CoA.
Plos One, 8, 2013
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4J4Z
 | | Crystal structure of the improved variant of the evolved serine hydrolase, OSH55.4_H1.2, bond with sulfate ion in the active site, Northeast Structural Genomics Consortium (NESG) Target OR301 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, Designed serine hydrolase variant OSH55.4_H1.2, ... | | Authors: | Kuzin, A.P, Lew, S, Rajagopalan, S, Maglaqui, M, Xiao, R, Lee, D, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2013-02-07 | | Release date: | 2013-03-06 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.26 Å) | | Cite: | Crystal structure of the improved variant of the evolved serine hydrolase, OSH55.4_H1.2, bond with sulfate ion in the active site, Northeast Structural Genomics Consortium (NESG) Target OR301
To be Published
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4IZB
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4HFX
 | | Crystal structure of a transcription elongation factor B polypeptide 3 from Homo sapiens, Northeast Structural Genomics consortium target id HR4748B. | | Descriptor: | SULFATE ION, Transcription elongation factor B polypeptide 3 | | Authors: | Seetharaman, J, Su, M, Ciccosanti, C, Sahdev, S, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2012-10-05 | | Release date: | 2012-12-12 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2.54 Å) | | Cite: | Crystal structure of a transcription elongation factor B polypeptide 3 from Homo sapiens, Northeast Structural Genomics consortium target id HR4748B. (CASP Target)
TO BE PUBLISHED
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4H3K
 | | Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA polymerase II CTD peptide phosphorylated at Ser-2, Ser-5 and Ser-7 | | Descriptor: | Hexapeptide, PHOSPHATE ION, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, ... | | Authors: | Xiang, K, Tong, L. | | Deposit date: | 2012-09-13 | | Release date: | 2012-10-31 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72.
Genes Dev., 26, 2012
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4J7N
 | | Crystal structure of mouse DXO in complex with M7GPPPG cap | | Descriptor: | 1,2-ETHANEDIOL, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, 9-METHYLGUANINE, ... | | Authors: | Kilic, T, Chang, J.H, Tong, L. | | Deposit date: | 2013-02-13 | | Release date: | 2013-03-27 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | A mammalian pre-mRNA 5' end capping quality control mechanism and an unexpected link of capping to pre-mRNA processing.
Mol.Cell, 50, 2013
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4IJB
 | | Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR288 | | Descriptor: | Engineered Protein OR288 | | Authors: | Vorobiev, S, Su, M, Bick, M.J, Seetharaman, J, Khare, S, Maglaqui, M, Xiao, R, Lee, D, Day, A, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Hunt, J, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2012-12-21 | | Release date: | 2013-01-16 | | Last modified: | 2013-02-27 | | Method: | X-RAY DIFFRACTION (1.739 Å) | | Cite: | Crystal Structure of Engineered Protein OR288.
To be Published
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4IOH
 | | Crystal Structure of the Tll1086 protein from Thermosynechococcus elongatus, Northeast Structural Genomics Consortium Target TeR258 | | Descriptor: | Tll1086 protein | | Authors: | Vorobiev, S, Su, M, Seetharaman, J, Maglaqui, M, Xiao, X, Kohan, E, Wang, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2013-01-07 | | Release date: | 2013-01-30 | | Last modified: | 2013-11-20 | | Method: | X-RAY DIFFRACTION (2.53 Å) | | Cite: | Crystal Structure of the Tll1086 protein from Thermosynechococcus elongatus.
To be Published
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4IZD
 | | Crystal structure of DmdD E121A in complex with MMPA-CoA | | Descriptor: | 3-methylmercaptopropionate-CoA (MMPA-CoA), Enoyl-CoA hydratase/isomerase family protein | | Authors: | Tan, D, Tong, L. | | Deposit date: | 2013-01-29 | | Release date: | 2013-06-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structure of DmdD, a Crotonase Superfamily Enzyme That Catalyzes the Hydration and Hydrolysis of Methylthioacryloyl-CoA.
Plos One, 8, 2013
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