7Q1Z
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![BU of 7q1z by Molmil](/molmil-images/mine/7q1z) | Structure of formaldehyde cross-linked SARS-CoV-2 S glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Sulbaran, G, Effantin, G, Schoehn, G, Weissenhorn, W. | Deposit date: | 2021-10-22 | Release date: | 2022-03-09 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Immunization with synthetic SARS-CoV-2 S glycoprotein virus-like particles protects macaques from infection. Cell Rep Med, 3, 2022
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8A1R
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![BU of 8a1r by Molmil](/molmil-images/mine/8a1r) | cryo-EM structure of thioredoxin glutathione reductase in complex with a non-competitive inhibitor | Descriptor: | (2~{R},3~{R},4~{S},5~{R})-2-[3-[[[(1~{R},2~{R},3~{R},5~{S})-2,6,6-trimethyl-3-bicyclo[3.1.1]heptanyl]amino]methyl]indol-1-yl]oxane-3,4,5-triol, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin glutathione reductase | Authors: | Ardini, M, Angelucci, F, Fata, F, Gabriele, F, Effantin, G, Ling, W, Williams, D.L, Petukhova, V.Z, Petukhov, P.A. | Deposit date: | 2022-06-01 | Release date: | 2023-06-14 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo. Nat Commun, 14, 2023
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4UFT
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![BU of 4uft by Molmil](/molmil-images/mine/4uft) | Structure of the helical Measles virus nucleocapsid | Descriptor: | 5'-R(*CP*CP*CP*CP*CP*CP)-3', NUCLEOPROTEIN | Authors: | Gutsche, I, Desfosses, A, Effantin, G, Ling, W.L, Haupt, M, Ruigrok, R.W.H, Sachse, C, Schoehn, G. | Deposit date: | 2015-03-19 | Release date: | 2015-04-29 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Near-Atomic Cryo-Em Structure of the Helical Measles Virus Nucleocapsid. Science, 348, 2015
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4UPB
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![BU of 4upb by Molmil](/molmil-images/mine/4upb) | Electron cryo-microscopy of the complex formed between the hexameric ATPase RavA and the decameric inducible decarboxylase LdcI | Descriptor: | ATPASE RAVA, LYSINE DECARBOXYLASE, INDUCIBLE | Authors: | Malet, H, Liu, K, El Bakkouri, M, Chan, S.W.S, Effantin, G, Bacia, M, Houry, W.A, Gutsche, I. | Deposit date: | 2014-06-15 | Release date: | 2014-08-20 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (11 Å) | Cite: | Assembly Principles of a Unique Cage Formed by Hexameric and Decameric E. Coli Proteins. Elife, 3, 2014
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4UPF
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![BU of 4upf by Molmil](/molmil-images/mine/4upf) | Assembly principles of the unique cage formed by the ATPase RavA hexamer and the lysine decarboxylase LdcI decamer | Descriptor: | ATPASE RAVA, LYSINE DECARBOXYLASE, INDUCIBLE | Authors: | Malet, H, Liu, K, El Bakkouri, M, Chan, S.W.S, Effantin, G, Bacia, M, Houry, W.A, Gutsche, I. | Deposit date: | 2014-06-16 | Release date: | 2014-08-20 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7.5 Å) | Cite: | Assembly Principles of a Unique Cage Formed by Hexameric and Decameric E. Coli Proteins. Elife, 3, 2014
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6GJ4
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![BU of 6gj4 by Molmil](/molmil-images/mine/6gj4) | Tubulin-6j complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-(quinolin-5-yl)naphtho[2,3-b]pyrrolo[1,2-d][1,4]oxazepin-4-yl acetate, CALCIUM ION, ... | Authors: | Brindisi, M, Ulivieri, C, Alfano, G, Gemma, S, Balaguer, F.d.A, Khan, T, Grillo, A, Chemi, G, Menchon, G, Prota, A.E, Olieric, N, Agell, D.L, Barasoain, I, Diaz, J.F, Nebbioso, A, Conte, M.R, Lopresti, L, Magnano, S, Amet, R, Kinsella, P, Zisterer, D.M, Ibrahim, O, O'Sullivan, J, Morbidelli, L, Spaccapelo, R, Baldari, C, Butini, S, Novellino, E, Campiani, G, Altucci, L, Steinmetz, M.O, Brogi, S. | Deposit date: | 2018-05-16 | Release date: | 2018-12-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents. Eur J Med Chem, 162, 2018
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6F3K
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![BU of 6f3k by Molmil](/molmil-images/mine/6f3k) | Combined solid-state NMR, solution-state NMR and EM data for structure determination of the tetrahedral aminopeptidase TET2 from P. horikoshii | Descriptor: | Tetrahedral aminopeptidase, ZINC ION | Authors: | Gauto, D.F, Estrozi, L.F, Schwieters, C.D, Effantin, G, Macek, P, Sounier, R, Kerfah, R, Sivertsen, A.C, Colletier, J.P, Boisbouvier, J, Schoehn, G, Favier, A, Schanda, P. | Deposit date: | 2017-11-28 | Release date: | 2018-03-14 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (4.1 Å), SOLID-STATE NMR, SOLUTION NMR | Cite: | Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex. Nat Commun, 10, 2019
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8B14
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![BU of 8b14 by Molmil](/molmil-images/mine/8b14) | T5 Receptor Binding Protein pb5 in complex with its E. coli receptor FhuA | Descriptor: | DECYLAMINE-N,N-DIMETHYL-N-OXIDE, FhuA iron-ferrichrome transporter, [(2R,3S,4R,5R,6R)-2-[[(2R,4R,5R,6R)-6-[(1R)-1,2-bis(oxidanyl)ethyl]-4-[(2R,4R,5R,6R)-6-[(1R)-1,2-bis(oxidanyl)ethyl]-2-carboxy-4,5-bis(oxidanyl)oxan-2-yl]oxy-2-carboxy-5-oxidanyl-oxan-2-yl]oxymethyl]-5-[[(3R)-3-dodecanoyloxytetradecanoyl]amino]-4-(3-nonanoyloxypropanoyloxy)-6-[[(2R,3S,4R,5R,6R)-3-oxidanyl-4-[(3S)-3-oxidanyltetradecanoyl]oxy-5-[[(3R)-3-oxidanyltridecanoyl]amino]-6-phosphonatooxy-oxan-2-yl]methoxy]oxan-3-yl] phosphate, ... | Authors: | Degroux, S, Effantin, G, Linares, R, Schoehn, G, Breyton, C. | Deposit date: | 2022-09-09 | Release date: | 2023-02-08 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Deciphering Bacteriophage T5 Host Recognition Mechanism and Infection Trigger. J.Virol., 97, 2023
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7QG9
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![BU of 7qg9 by Molmil](/molmil-images/mine/7qg9) | Tail tip of siphophage T5 : common core proteins | Descriptor: | Distal tail protein, L-shaped tail fiber protein p132, Minor tail protein, ... | Authors: | Linares, R, Arnaud, C.A, Effantin, G, Darnault, C, Epalle, N, Boeri Erba, E, Schoehn, G, Breyton, C. | Deposit date: | 2021-12-07 | Release date: | 2022-12-21 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Structural basis of bacteriophage T5 infection trigger and E. coli cell wall perforation. Sci Adv, 9, 2023
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6R8N
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![BU of 6r8n by Molmil](/molmil-images/mine/6r8n) | STRUCTURE DETERMINATION OF THE TETRAHEDRAL AMINOPEPTIDASE TET2 FROM P. HORIKOSHII BY USE OF COMBINED SOLID-STATE NMR, SOLUTION-STATE NMR AND EM DATA 4.1 A, FOLLOWED BY REAL_SPACE_REFINEMENT AT 4.1 A | Descriptor: | Tetrahedral aminopeptidase, ZINC ION | Authors: | Colletier, J.-P, Gauto, D, Estrozi, L, Favier, A, Effantin, G, Schoehn, G, Boisbouvier, J, Schanda, P. | Deposit date: | 2019-04-02 | Release date: | 2019-08-14 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (4.1 Å), SOLUTION NMR | Cite: | Integrated NMR and cryo-EM atomic-resolution structure determination of a half-megadalton enzyme complex. Nat Commun, 10, 2019
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6Z6G
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![BU of 6z6g by Molmil](/molmil-images/mine/6z6g) | Cryo-EM structure of La Crosse virus polymerase at pre-initiation stage | Descriptor: | 3'vRNA 1-16, 5'vRNA 1-10, 5'vRNA 9-16, ... | Authors: | Arragain, B, Effantin, G, Gerlach, P, Reguera, J, Schoehn, G, Cusack, S, Malet, H. | Deposit date: | 2020-05-28 | Release date: | 2020-07-29 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes. Nat Commun, 11, 2020
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6Z8K
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![BU of 6z8k by Molmil](/molmil-images/mine/6z8k) | La Crosse virus polymerase at elongation mimicking stage | Descriptor: | La Crosse virus 3' vRNA (1-16), La Crosse virus 5' vRNA (9-16), La Crosse virus 5' vRNA 1-10, ... | Authors: | Arragain, B, Effantin, G, Schoehn, G, Cusack, S, Malet, H. | Deposit date: | 2020-06-02 | Release date: | 2020-07-29 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes. Nat Commun, 11, 2020
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6YN5
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![BU of 6yn5 by Molmil](/molmil-images/mine/6yn5) | Inducible lysine decarboxylase LdcI decamer, pH 7.0 | Descriptor: | Inducible lysine decarboxylase | Authors: | Jessop, M, Felix, J, Desfosses, A, Effantin, G, Gutsche, I. | Deposit date: | 2020-04-10 | Release date: | 2021-01-13 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Supramolecular assembly of the Escherichia coli LdcI upon acid stress. Proc.Natl.Acad.Sci.USA, 118, 2021
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6YN6
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![BU of 6yn6 by Molmil](/molmil-images/mine/6yn6) | Inducible lysine decarboxylase LdcI stacks, pH 5.7 | Descriptor: | Inducible lysine decarboxylase | Authors: | Felix, J, Jessop, M, Desfosses, A, Effantin, G, Gutsche, I. | Deposit date: | 2020-04-10 | Release date: | 2021-01-13 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Supramolecular assembly of the Escherichia coli LdcI upon acid stress. Proc.Natl.Acad.Sci.USA, 118, 2021
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1DUJ
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![BU of 1duj by Molmil](/molmil-images/mine/1duj) | SOLUTION STRUCTURE OF THE SPINDLE ASSEMBLY CHECKPOINT PROTEIN HUMAN MAD2 | Descriptor: | SPINDLE ASSEMBLY CHECKPOINT PROTEIN | Authors: | Luo, X, Fang, G, Coldiron, M, Lin, Y, Yu, H. | Deposit date: | 2000-01-17 | Release date: | 2000-03-08 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20. Nat.Struct.Biol., 7, 2000
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5NGJ
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![BU of 5ngj by Molmil](/molmil-images/mine/5ngj) | Crystal structure of pb6, major tail tube protein of bacteriophage T5 | Descriptor: | CHLORIDE ION, Tail tube protein | Authors: | Arnaud, C.-A, Effantin, G, Vives, C, Engilberge, S, Bacia, M, Boulanger, P, Girard, E, Schoehn, G, Breyton, C. | Deposit date: | 2017-03-17 | Release date: | 2018-01-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Bacteriophage T5 tail tube structure suggests a trigger mechanism for Siphoviridae DNA ejection. Nat Commun, 8, 2017
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2MLW
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![BU of 2mlw by Molmil](/molmil-images/mine/2mlw) | New Cyt-like delta-endotoxins from Dickeya dadantii - CytC protein | Descriptor: | Type-1Ba cytolytic delta-endotoxin | Authors: | Loth, K, Costechareyre, D, Effantin, G, Rahbe, Y, Condemine, G, Landon, C, Da Silva, P. | Deposit date: | 2014-03-05 | Release date: | 2015-02-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | New Cyt-like delta-endotoxins from Dickeya dadantii: structure and aphicidal activity. Sci Rep, 5, 2015
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6RLP
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![BU of 6rlp by Molmil](/molmil-images/mine/6rlp) | Cryo-EM reconstruction of TMV coat protein | Descriptor: | Capsid protein, RNA (5'-R(P*GP*AP*A)-3') | Authors: | Kandiah, E, Effantin, G. | Deposit date: | 2019-05-02 | Release date: | 2022-11-23 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | CM01: a facility for cryo-electron microscopy at the European Synchrotron. Acta Crystallogr D Struct Biol, 75, 2019
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8BCU
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![BU of 8bcu by Molmil](/molmil-images/mine/8bcu) | |
8BCP
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![BU of 8bcp by Molmil](/molmil-images/mine/8bcp) | |
2Q9N
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![BU of 2q9n by Molmil](/molmil-images/mine/2q9n) | 4-Substituted Trinems as Broad Spectrum-Lactamase Inhibitors: Structure-based Design, Synthesis and Biological Activity | Descriptor: | (1S,4R,7AR)-4-BUTOXY-1-[(1R)-1-FORMYLPROPYL]-2,4,5,6,7,7A-HEXAHYDRO-1H-ISOINDOLE-3-CARBOXYLIC ACID, Beta-lactamase | Authors: | Plantan, I, Selic, L, Mesar, T, Stefanic Anderluh, P, Oblak, M, Prezelj, A, Hesse, L, Andrejasic, M, Vilar, M, Turk, D, Kocijan, A, Prevec, T, Vilfan, G, Kocjan, D, Copar, A, Urleb, U, Solmajer, T. | Deposit date: | 2007-06-13 | Release date: | 2007-08-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | 4-Substituted Trinems as Broad Spectrum beta-Lactamase Inhibitors: Structure-Based Design, Synthesis, and Biological Activity J.Med.Chem., 50, 2007
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8EVG
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![BU of 8evg by Molmil](/molmil-images/mine/8evg) | |
2Q9M
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![BU of 2q9m by Molmil](/molmil-images/mine/2q9m) | 4-Substituted Trinems as Broad Spectrum-Lactamase Inhibitors: Structure-based Design, Synthesis and Biological Activity | Descriptor: | (1R,4S,7AS)-1-(1-FORMYLPROP-1-EN-1-YL)-4-METHOXY-2,4,5,6,7,7A-HEXAHYDRO-1H-ISOINDOLE-3-CARBOXYLIC ACID, Beta-lactamase | Authors: | Plantan, I, Selic, L, Mesar, T, Stefanic Anderluh, P, Oblak, M, Prezelj, A, Hesse, L, Andrejasic, M, Vilar, M, Turk, D, Kocijan, A, Prevec, T, Vilfan, G, Kocjan, D, Copar, A, Urleb, U, Solmajer, T. | Deposit date: | 2007-06-13 | Release date: | 2007-08-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | 4-Substituted Trinems as Broad Spectrum beta-Lactamase Inhibitors: Structure-Based Design, Synthesis, and Biological Activity J.Med.Chem., 50, 2007
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4D80
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![BU of 4d80 by Molmil](/molmil-images/mine/4d80) | Metallosphera sedula Vps4 crystal structure | Descriptor: | AAA ATPASE, CENTRAL DOMAIN PROTEIN | Authors: | Caillat, C, Macheboeuf, P, Wu, Y, McCarthy, A.A, Boeri-Erba, E, Effantin, G, Gottlinger, H.G, Weissenhorn, W, Renesto, P. | Deposit date: | 2014-12-02 | Release date: | 2015-10-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Asymmetric Ring Structure of Vps4 Required for Escrt-III Disassembly. Nat.Commun., 6, 2015
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4D82
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![BU of 4d82 by Molmil](/molmil-images/mine/4d82) | Metallosphera sedula Vps4 crystal structure | Descriptor: | AAA ATPase, central domain protein, ADENOSINE-5'-DIPHOSPHATE | Authors: | Caillat, C, Macheboeuf, P, Wu, Y, McCarthy, A.A, Boeri-Erba, E, Effantin, G, Gottlinger, H.G, Weissenhorn, W, Renesto, P. | Deposit date: | 2014-12-02 | Release date: | 2015-11-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Asymmetric Ring Structure of Vps4 Required for Escrt-III Disassembly. Nat.Commun., 6, 2015
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