1Z25
 
 | | Structure of P.furiosus Argonaute with bound Mn2+ | | Descriptor: | Argonaute, MANGANESE (II) ION | | Authors: | Rivas, F.V, Tolia, N.H, Song, J.J, Aragon, J.P, Liu, J, Hannon, G.J, Joshua-Tor, L. | | Deposit date: | 2005-03-07 | | Release date: | 2005-04-05 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Purified Argonaute2 and an siRNA form recombinant human RISC.
Nat.Struct.Mol.Biol., 12, 2005
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1Z26
 | | Structure of Pyrococcus furiosus Argonaute with bound tungstate | | Descriptor: | Argonaute, TUNGSTATE(VI)ION | | Authors: | Rivas, F.V, Tolia, N.H, Song, J.J, Aragon, J.P, Liu, J, Hannon, G.J, Joshua-Tor, L. | | Deposit date: | 2005-03-07 | | Release date: | 2005-04-05 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Purified Argonaute2 and an siRNA form recombinant human RISC.
Nat.Struct.Mol.Biol., 12, 2005
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4GF2
 | | Crystal structure of Plasmodium falciparum Erythrocyte Binding Antigen 140 (PfEBA-140/BAEBL) | | Descriptor: | Erythrocyte binding antigen 140, GLYCEROL | | Authors: | Lin, D.H, Malpede, B.M, Batchelor, J.D, Tolia, N.H. | | Deposit date: | 2012-08-02 | | Release date: | 2012-09-26 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal and Solution Structures of Plasmodium falciparum Erythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion.
J.Biol.Chem., 287, 2012
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6WG9
 | | Crystal structure of tetracycline destructase Tet(X7) | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Tetracycline destructase Tet(X7) | | Authors: | Kumar, H, Tolia, N.H. | | Deposit date: | 2020-04-05 | | Release date: | 2021-02-10 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance.
Commun Biol, 3, 2020
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8DCE
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4QEX
 | | Crystal structure of PfEBA-175 RII in complex with a Fab fragment from inhibitory antibody R217 | | Descriptor: | Antibody Heavy Chain, Antibody Light Chain, Erythrocyte-binding antigen-175 | | Authors: | Chen, E, Paing, M.M, Salinas, N, Sim, B.K, Tolia, N.H. | | Deposit date: | 2014-05-19 | | Release date: | 2014-06-04 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (4.5 Å) | | Cite: | Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175.
Plos Pathog., 9, 2013
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4ZEX
 | | Crystal structure of PfHAD1 in complex with glyceraldehyde-3-phosphate | | Descriptor: | GLYCERALDEHYDE-3-PHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | | Authors: | Park, J, Tolia, N.H. | | Deposit date: | 2015-04-20 | | Release date: | 2015-09-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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4ZEW
 | | Crystal structure of PfHAD1 in complex with glucose-6-phosphate | | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, PHOSPHATE ION, ... | | Authors: | Park, J, Tolia, N.H. | | Deposit date: | 2015-04-20 | | Release date: | 2015-09-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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4ZEV
 | | Crystal structure of PfHAD1 in complex with mannose-6-phosphate | | Descriptor: | 6-O-phosphono-alpha-D-mannopyranose, MAGNESIUM ION, PHOSPHATE ION, ... | | Authors: | Park, J, Tolia, N.H. | | Deposit date: | 2015-04-20 | | Release date: | 2015-09-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Cap-domain closure enables diverse substrate recognition by the C2-type haloacid dehalogenase-like sugar phosphatase Plasmodium falciparum HAD1.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
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4YFS
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8DFG
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8DFH
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8DFI
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8E1Z
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8ER1
 | | X-ray crystal structure of Tet(X6) | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase | | Authors: | Kumar, H, Tolia, N.H. | | Deposit date: | 2022-10-11 | | Release date: | 2023-04-26 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases.
Commun Biol, 6, 2023
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8ER0
 | | X-ray crystal structure of Tet(X6) bound to anhydrotetracycline | | Descriptor: | 5A,6-ANHYDROTETRACYCLINE, FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase | | Authors: | Kumar, H, Tolia, N.H. | | Deposit date: | 2022-10-11 | | Release date: | 2023-04-26 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of anhydrotetracycline-bound Tet(X6) reveals the mechanism for inhibition of type 1 tetracycline destructases.
Commun Biol, 6, 2023
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8EZM
 | | Pfs25 in complex with transmission-reducing antibody AS01-63 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, SULFATE ION, ... | | Authors: | Shukla, N, Tang, W.K, Tolia, N.H. | | Deposit date: | 2022-11-01 | | Release date: | 2023-08-16 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
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8EZK
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8EZL
 | | Pfs25 in complex with transmission-reducing antibody AS01-50 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 25 kDa ookinete surface antigen, Transmission-reducing antibody AS01-50, ... | | Authors: | Shukla, N, Tang, W.K, Tolia, N.H. | | Deposit date: | 2022-11-01 | | Release date: | 2023-08-16 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A human antibody epitope map of the malaria vaccine antigen Pfs25.
Npj Vaccines, 8, 2023
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7UFW
 | | Pfs230 D1D2 in complex with LMIV230-01 | | Descriptor: | Gametocyte surface protein P230, LMIV230-01 | | Authors: | Tang, W.K, Tolia, N.H. | | Deposit date: | 2022-03-23 | | Release date: | 2023-02-15 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
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7UA8
 | | Pfs230 D1 domain in complex with 230AL-20 | | Descriptor: | 230Al-20, Gametocyte surface protein P230 | | Authors: | Tang, W.K, Tolia, N.H. | | Deposit date: | 2022-03-11 | | Release date: | 2023-02-15 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
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7UA2
 | | Pfs230 D1 domain in complex with 230AL-18 | | Descriptor: | 230AL-18, Gametocyte surface protein P230, LMIV230-01 | | Authors: | Tang, W.K, Tolia, N.H. | | Deposit date: | 2022-03-11 | | Release date: | 2023-02-15 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
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7U9W
 | | Pfs230 D1 domain in complex with 230AS-88 | | Descriptor: | 230AS-88, Gametocyte surface protein P230 | | Authors: | Tang, W.K, Tolia, N.H. | | Deposit date: | 2022-03-11 | | Release date: | 2023-02-15 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
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7UBS
 | | Pfs230 D1 domain in complex with 230AS-26 | | Descriptor: | 230AS-26, Gametocyte surface protein P230 | | Authors: | Tang, W.K, Tolia, N.H. | | Deposit date: | 2022-03-15 | | Release date: | 2023-02-15 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
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7UCQ
 | | Pfs230 D1 domain in complex with 230AS-18 | | Descriptor: | 230AS-18, Gametocyte surface protein P230 | | Authors: | Tang, W.K, Tolia, N.H. | | Deposit date: | 2022-03-17 | | Release date: | 2023-02-15 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A human antibody epitope map of Pfs230D1 derived from analysis of individuals vaccinated with a malaria transmission-blocking vaccine.
Immunity, 56, 2023
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