2GWJ
| |
2GWL
| |
2GWM
| |
3BEO
| A Structural Basis for the allosteric regulation of non-hydrolyzing UDP-GlcNAc 2-epimerases | Descriptor: | UDP-N-acetylglucosamine 2-epimerase, URIDINE-5'-DIPHOSPHATE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | Authors: | Velloso, L.M, Bhaskaran, S.S, Schuch, R, Fischetti, V.A, Stebbins, C.E. | Deposit date: | 2007-11-19 | Release date: | 2008-02-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A structural basis for the allosteric regulation of non-hydrolysing UDP-GlcNAc 2-epimerases. Embo Rep., 9, 2008
|
|
8Q0P
| |
8Q0E
| |
4MI7
| |
2P2L
| Rac1-GDP-Zinc Complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Ras-related C3 botulinum toxin substrate 1, ZINC ION | Authors: | Prehna, G, Stebbins, C.E. | Deposit date: | 2007-03-07 | Release date: | 2007-05-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A Rac1-GDP trimer complex binds zinc with tetrahedral and octahedral coordination, displacing magnesium. Acta Crystallogr.,Sect.D, 63, 2007
|
|
8OK4
| Variant Surface Glycoprotein VSG11wt-Oil | Descriptor: | Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Zeelen, J.P, Stebbins, C.E, Aresta-Branco, F, Foti, K. | Deposit date: | 2023-03-27 | Release date: | 2023-09-13 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (1.23 Å) | Cite: | A structural classification of the variant surface glycoproteins of the African trypanosomey. Plos Negl Trop Dis, 17, 2023
|
|
8ONH
| Variant Surface Glycoprotein VSG11wt-Oil | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein, alpha-D-glucopyranose, ... | Authors: | Zeelen, J.P, Stebbins, C.E, Foti, K, Gkeka, A, Vlachou, E.P. | Deposit date: | 2023-04-03 | Release date: | 2023-09-13 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | A structural classification of the variant surface glycoproteins of the African trypanosomey. Plos Negl Trop Dis, 17, 2023
|
|
8OK8
| Variant Surface Glycoprotein VSG615 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein 615, ... | Authors: | Zeelen, J.P, Stebbins, C.E, Chandra, M. | Deposit date: | 2023-03-27 | Release date: | 2023-09-13 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (3.22 Å) | Cite: | A structural classification of the variant surface glycoproteins of the African trypanosomey. Plos Negl Trop Dis, 17, 2023
|
|
8OK5
| Variant Surface Glycoprotein VSG11 monomer with iodine | Descriptor: | IODIDE ION, Variant surface glycoprotein, alpha-D-glucopyranose, ... | Authors: | Zeelen, J.P, Stebbins, C.E, Aresta-Branco, F. | Deposit date: | 2023-03-27 | Release date: | 2023-09-13 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | A structural classification of the variant surface glycoproteins of the African trypanosomey. Plos Negl Trop Dis, 17, 2023
|
|
8OK6
| Variant Surface Glycoprotein VSG11 two monomers | Descriptor: | SULFATE ION, Variant surface glycoprotein, alpha-D-glucopyranose, ... | Authors: | Gkeka, A, Vlachou, E.P, Zeelen, J.P, Stebbins, C.E. | Deposit date: | 2023-03-27 | Release date: | 2023-09-13 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | A structural classification of the variant surface glycoproteins of the African trypanosomey. Plos Negl Trop Dis, 17, 2023
|
|
8OK7
| Variant Surface Glycoprotein VSG558 NTD | Descriptor: | Variant surface glycoprotein 558, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zeelen, J.P, Stebbins, C.E, van Straaten, M, Zhong, J. | Deposit date: | 2023-03-27 | Release date: | 2023-09-13 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | A structural classification of the variant surface glycoproteins of the African trypanosomey. Plos Negl Trop Dis, 17, 2023
|
|
3G06
| |
7P56
| Variant Surface Glycoprotein 2 (VSG2, MiTat1.2, VSG221) Bound to Calcium | Descriptor: | CALCIUM ION, Variant surface glycoprotein MITAT 1.2, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Gkeka, A, Aresta-Branco, F, Stebbins, C.E, Papavasiliou, F.N. | Deposit date: | 2021-07-14 | Release date: | 2022-07-27 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (1.735 Å) | Cite: | Immunodominant surface epitopes power immune evasion in the African trypanosome. Cell Rep, 42, 2023
|
|
7P5D
| Variant Surface Glycoprotein 3 (VSG3, MiTat1.3, VSG224) mutant (serine 317 and 319 to alanine) | Descriptor: | Variant surface glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Gkeka, A, Aresta-Branco, F, Stebbins, C.E, Papavasiliou, F.N. | Deposit date: | 2021-07-14 | Release date: | 2022-07-27 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Immunodominant surface epitopes power immune evasion in the African trypanosome. Cell Rep, 42, 2023
|
|
7P57
| VSG2 mutant structure lacking the calcium binding pocket | Descriptor: | Variant surface glycoprotein MITAT 1.2, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Gkeka, A, Aresta-Branco, F, Stebbins, C.E, Papavasiliou, F.N. | Deposit date: | 2021-07-14 | Release date: | 2022-07-27 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (1.961 Å) | Cite: | Immunodominant surface epitopes power immune evasion in the African trypanosome. Cell Rep, 42, 2023
|
|
7P59
| Variant Surface Glycoprotein 3 (VSG3, MiTat1.3, VSG224) with two O-linked post-translational modifications | Descriptor: | Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Gkeka, A, Arest-Branco, F, Stebbins, C.E, Papavasiliou, F.N. | Deposit date: | 2021-07-14 | Release date: | 2022-07-27 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | Immunodominant surface epitopes power immune evasion in the African trypanosome. Cell Rep, 42, 2023
|
|
7P5B
| Variant Surface Glycoprotein 3 (VSG3, MiTat1.3, VSG224) mutant (serine 319 to alanine), single O-linked glycosylated at Ser317 | Descriptor: | Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Gkeka, A, Aresta-Branco, F, Stebbins, C.E, Papavasiliou, F.N. | Deposit date: | 2021-07-14 | Release date: | 2022-07-27 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.13 Å) | Cite: | Immunodominant surface epitopes power immune evasion in the African trypanosome. Cell Rep, 42, 2023
|
|
7P5A
| Variant Surface Glycoprotein 3 (VSG3, MiTat1.3, VSG224) mutant (serine 317 to alanine), single O-linked glycosylated at Ser319 | Descriptor: | Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Gkeka, A, Aresta-Branco, F, Stebbins, C.E, Papavasiliou, F.N. | Deposit date: | 2021-07-14 | Release date: | 2022-07-27 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Immunodominant surface epitopes power immune evasion in the African trypanosome. Cell Rep, 42, 2023
|
|
8B3W
| Structure of metacyclic VSG (mVSG) 1954 from Trypanosoma brucei | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, Variant surface glycoprotein 1954 | Authors: | Chandra, M, Stebbins, C.E. | Deposit date: | 2022-09-17 | Release date: | 2023-01-25 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (1.681 Å) | Cite: | Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome. Plos Negl Trop Dis, 17, 2023
|
|
8B3B
| Structure of metacyclic VSG (mVSG) 531 from Trypanosoma brucei | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein 531, alpha-D-mannopyranose, ... | Authors: | Chandra, M, Stebbins, C.E. | Deposit date: | 2022-09-16 | Release date: | 2023-01-25 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (1.949 Å) | Cite: | Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome. Plos Negl Trop Dis, 17, 2023
|
|
8B3E
| Variant Surface Glycoprotein VSG397 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein 397 | Authors: | Zeelen, J.P, Stebbins, C.E, Dakovic, S, Foti, K. | Deposit date: | 2022-09-16 | Release date: | 2023-01-25 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (1.26 Å) | Cite: | Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome. Plos Negl Trop Dis, 17, 2023
|
|
7QT2
| Antibody FenAb208 - fentanyl complex | Descriptor: | Antibody heavy chain, Antibody light chain, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide | Authors: | Zeelen, J.P, Straaten van, M, Stebbins, C.E. | Deposit date: | 2022-01-14 | Release date: | 2023-05-24 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl. Cell Rep, 42, 2023
|
|