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7TNY
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BU of 7tny by Molmil
Cryo-EM structure of RIG-I in complex with p2dsRNA
Descriptor: Antiviral innate immune response receptor RIG-I, ZINC ION, p2dsRNA
Authors:Wang, W, Pyle, A.M.
Deposit date:2022-01-22
Release date:2022-11-02
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
5WDX
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BU of 5wdx by Molmil
Structure of NS3 from HCV strain JFH-1 that is an unusually robust helicase that is primed to bind and unwind viral RNA
Descriptor: JFH-1 NS3, MAGNESIUM ION, ZINC ION
Authors:Zhou, T, Pyle, A.M.
Deposit date:2017-07-06
Release date:2017-11-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:NS3 from Hepatitis C Virus Strain JFH-1 Is an Unusually Robust Helicase That Is Primed To Bind and Unwind Viral RNA.
J. Virol., 92, 2018
8T2R
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BU of 8t2r by Molmil
Structure of a group II intron ribonucleoprotein in the pre-ligation (pre-2F) state
Descriptor: 5'exon, AMMONIUM ION, CALCIUM ION, ...
Authors:Xu, L, Liu, T, Chung, K, Pyle, A.M.
Deposit date:2023-06-06
Release date:2023-11-22
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into intron catalysis and dynamics during splicing.
Nature, 624, 2023
8T2S
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BU of 8t2s by Molmil
Structure of a group II intron ribonucleoprotein in the pre-branching (pre-1F) state
Descriptor: AMMONIUM ION, CALCIUM ION, Group II intron reverse transcriptase/maturase, ...
Authors:Xu, L, Liu, T, Chung, K, Pyle, A.M.
Deposit date:2023-06-06
Release date:2023-11-22
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into intron catalysis and dynamics during splicing.
Nature, 624, 2023
8T2T
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BU of 8t2t by Molmil
Structure of a group II intron ribonucleoprotein in the post-ligation (post-2F) state
Descriptor: AMMONIUM ION, Group II intron reverse transcriptase/maturase, MAGNESIUM ION, ...
Authors:Xu, L, Liu, T, Chung, K, Pyle, A.M.
Deposit date:2023-06-06
Release date:2023-11-22
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into intron catalysis and dynamics during splicing.
Nature, 624, 2023
8SD0
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BU of 8sd0 by Molmil
Cryo-EM structure of RIG-I in complex with p3SLR14
Descriptor: Antiviral innate immune response receptor RIG-I, ZINC ION, p3SLR14
Authors:Wang, W, Pyle, A.M.
Deposit date:2023-04-06
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of RIG-I in complex with p3SLR14
To Be Published
8SCZ
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BU of 8scz by Molmil
Cryo-EM structure of 14aa-GS RIG-I in complex with p3SLR30
Descriptor: Antiviral innate immune response receptor RIG-I, ZINC ION, p3SLR30
Authors:Wang, W, Pyle, A.M.
Deposit date:2023-04-06
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of 14aa-GS RIG-I in complex with p3SLR30
To Be Published
3IGI
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BU of 3igi by Molmil
Tertiary Architecture of the Oceanobacillus Iheyensis Group II Intron
Descriptor: 5'-R(*CP*GP*CP*UP*CP*UP*AP*CP*UP*CP*UP*AP*U)-3', Group IIC intron, MAGNESIUM ION, ...
Authors:Toor, N, Keating, K.S, Fedorova, O, Rajashankar, K, Wang, J, Pyle, A.M.
Deposit date:2009-07-27
Release date:2009-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.125 Å)
Cite:Tertiary architecture of the Oceanobacillus iheyensis group II intron.
Rna, 16, 2010
6T3N
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BU of 6t3n by Molmil
Structure of Oceanobacillus iheyensis group II intron G-mutant (C289G/C358G/G385C) in the presence of Na+, Mg2+ and 5'-exon
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Group IIC Intron Ribozyme, MAGNESIUM ION, ...
Authors:Marcia, M, Pyle, A.M.
Deposit date:2019-10-11
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Visualizing group II intron dynamics between the first and second steps of splicing.
Nat Commun, 11, 2020
6T3K
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BU of 6t3k by Molmil
Structure of Oceanobacillus iheyensis group II intron G-mutant (C289G/C358G/G385C) in the presence of K+, Mg2+ and 5'-exon
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Group IIC Intron Ribozyme, MAGNESIUM ION, ...
Authors:Marcia, M, Pyle, A.M.
Deposit date:2019-10-11
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.44 Å)
Cite:Visualizing group II intron dynamics between the first and second steps of splicing.
Nat Commun, 11, 2020
6T3S
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BU of 6t3s by Molmil
Structure of Oceanobacillus iheyensis group II intron U-mutant (C289U/C358U/G385A) in the presence of Na+, Mg2+ and 5'-exon
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Group IIC Intron Ribozyme, MAGNESIUM ION, ...
Authors:Marcia, M, Pyle, A.M.
Deposit date:2019-10-11
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Visualizing group II intron dynamics between the first and second steps of splicing.
Nat Commun, 11, 2020
6T3R
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BU of 6t3r by Molmil
Structure of Oceanobacillus iheyensis group II intron U-mutant (C289U/C358U/G385A) in the presence of K+, Mg2+ and 5'-exon
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Group IIC Intron Ribozyme, MAGNESIUM ION, ...
Authors:Marcia, M, Pyle, A.M.
Deposit date:2019-10-11
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.57 Å)
Cite:Visualizing group II intron dynamics between the first and second steps of splicing.
Nat Commun, 11, 2020
5HHL
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BU of 5hhl by Molmil
Reverse transcriptase domain of group II intron maturase from Eubacterium rectale in P21 space group
Descriptor: POTASSIUM ION, Retron-type reverse transcriptase
Authors:Zhao, C, Pyle, A.M.
Deposit date:2016-01-11
Release date:2016-05-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
5HHK
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BU of 5hhk by Molmil
Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P21 space group (Se-MET)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, PHOSPHATE ION, ...
Authors:Zhao, C, Pyle, A.M.
Deposit date:2016-01-11
Release date:2016-05-04
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
5IRG
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BU of 5irg by Molmil
Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P212121 space group
Descriptor: POTASSIUM ION, Retron-type reverse transcriptase
Authors:Zhao, C, Pyle, A.M.
Deposit date:2016-03-13
Release date:2016-05-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
5HHJ
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BU of 5hhj by Molmil
Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P21 space group
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, PHOSPHATE ION, ...
Authors:Zhao, C, Pyle, A.M.
Deposit date:2016-01-11
Release date:2016-05-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
5IRF
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BU of 5irf by Molmil
Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P1 space group
Descriptor: POTASSIUM ION, Retron-type reverse transcriptase
Authors:Zhao, C, Pyle, A.M.
Deposit date:2016-03-13
Release date:2016-05-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
3EOG
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BU of 3eog by Molmil
Co-crystallization showing exon recognition by a group II intron
Descriptor: 5'-R(*UP*UP*AP*UP*UP*A)-3', Group IIC intron, MAGNESIUM ION, ...
Authors:Toor, N, Rajashankar, K, Keating, K.S, Pyle, A.M.
Deposit date:2008-09-26
Release date:2008-10-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.391 Å)
Cite:Structural basis for exon recognition by a group II intron.
Nat.Struct.Mol.Biol., 15, 2008
3EOH
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BU of 3eoh by Molmil
Refined group II intron structure
Descriptor: 5'-R(*UP*UP*AP*UP*UP*A)-3', Group IIC intron, MAGNESIUM ION, ...
Authors:Toor, N, Rajashankar, K, Keating, K.S, Pyle, A.M.
Deposit date:2008-09-26
Release date:2008-10-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.125 Å)
Cite:Structural basis for exon recognition by a group II intron.
Nat.Struct.Mol.Biol., 15, 2008
4AY2
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BU of 4ay2 by Molmil
Capturing 5' tri-phosphorylated RNA duplex by RIG-I
Descriptor: 5'-R-PPP(GP*GP*CP*GP*CP*GP*GP*CP*UP*UP*CP*GP*GP*CP *CP*GP*CP*GP*CP*C)-3', ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Luo, D, Pyle, A.M.
Deposit date:2012-06-17
Release date:2012-10-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Visualizing the Determinants of Viral RNA Recognition by Innate Immune Sensor Rig-I.
Structure, 20, 2012
4E8N
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BU of 4e8n by Molmil
Structure of Oceanobacillus iheyensis group II intron in a ligand-free state in the presence of NH4+ and Mg2+
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AMMONIUM ION, Group IIC intron, ...
Authors:Marcia, M, Pyle, A.M.
Deposit date:2012-03-20
Release date:2012-11-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Visualizing Group II Intron Catalysis through the Stages of Splicing.
Cell(Cambridge,Mass.), 151, 2012
4E8Q
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BU of 4e8q by Molmil
Structure of Oceanobacillus iheyensis group II intron in a ligand-free state in the presence of Tl+ and Mg2+
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Group IIC intron, MAGNESIUM ION, ...
Authors:Marcia, M, Pyle, A.M.
Deposit date:2012-03-20
Release date:2012-11-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Visualizing Group II Intron Catalysis through the Stages of Splicing.
Cell(Cambridge,Mass.), 151, 2012
4E8V
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BU of 4e8v by Molmil
Structure of Oceanobacillus iheyensis group II intron in a ligand-free state in the presence of K+ and Ba2+
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BARIUM ION, Group IIC intron, ...
Authors:Marcia, M, Pyle, A.M.
Deposit date:2012-03-20
Release date:2012-11-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.995 Å)
Cite:Visualizing Group II Intron Catalysis through the Stages of Splicing.
Cell(Cambridge,Mass.), 151, 2012
4BPB
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BU of 4bpb by Molmil
STRUCTURAL INSIGHTS INTO RNA RECOGNITION BY RIG-I
Descriptor: 5'-R(*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP)-3', PROBABLE ATP-DEPENDENT RNA HELICASE DDX58, SULFATE ION, ...
Authors:Luo, D, Pyle, A.M.
Deposit date:2013-05-23
Release date:2013-06-19
Method:X-RAY DIFFRACTION (2.584 Å)
Cite:Structural Insights Into RNA Recognition by Rig-I.
Cell(Cambridge,Mass.), 147, 2011
4E8P
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BU of 4e8p by Molmil
Structure of Oceanobacillus iheyensis group II intron in a ligand-free state in the presence of Rb+ and Mg2+
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Group IIC intron, MAGNESIUM ION, ...
Authors:Marcia, M, Pyle, A.M.
Deposit date:2012-03-20
Release date:2012-11-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:Visualizing Group II Intron Catalysis through the Stages of Splicing.
Cell(Cambridge,Mass.), 151, 2012

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