4DS6

Crystal structure of a group II intron in the pre-catalytic state

Summary for 4DS6

Entry DOI	10.2210/pdb4ds6/pdb
Descriptor	Mutant Group IIC Intron, MAGNESIUM ION (3 entities in total)
Functional Keywords	rna, ribonucleic acid, intron, group ii
Biological source	Oceanobacillus iheyensis
Total number of polymer chains	1
Total formula weight	137288.94
Authors	Chan, R.T.,Robart, A.R.,Rajashankar, K.R.,Pyle, A.M.,Toor, N. (deposition date: 2012-02-17, release date: 2012-04-18, Last modification date: 2023-09-13)
Primary citation	Chan, R.T.,Robart, A.R.,Rajashankar, K.R.,Pyle, A.M.,Toor, N. Crystal structure of a group II intron in the pre-catalytic state. Nat.Struct.Mol.Biol., 19:555-557, 2012 Cited by PubMed Abstract: Group II introns are self-splicing catalytic RNAs that are thought to be ancestral to the spliceosome. Here we report the 3.65-Å crystal structure of the group II intron from Oceanobacillus iheyensis in the pre-catalytic state. The structure reveals the conformation of the 5' splice site in the catalytic core and represents the first structure of an intron prior to the first step of splicing. PubMed: 22484319 DOI: 10.1038/nsmb.2270 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.644 Å)

Structure validation