2YRX
 
 | | Crystal structure of GAR synthetase from Geobacillus kaustophilus | | Descriptor: | ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, Phosphoribosylglycinamide synthetase | | Authors: | Baba, S, Kanagawa, M, Kuramitsu, S, Yokoyama, S, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-04-03 | | Release date: | 2007-10-09 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structures of glycinamide ribonucleotide synthetase, PurD, from thermophilic eubacteria
J.Biochem., 148, 2010
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2YYA
 | | Crystal structure of GAR synthetase from Aquifex aeolicus | | Descriptor: | Phosphoribosylamine--glycine ligase | | Authors: | Baba, S, Kanagawa, M, Kuramitsu, S, Yokoyama, S, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-04-27 | | Release date: | 2007-10-30 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structures of glycinamide ribonucleotide synthetase, PurD, from thermophilic eubacteria
J.Biochem., 148, 2010
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2YRW
 | | Crystal structure of GAR synthetase from Geobacillus kaustophilus | | Descriptor: | PHOSPHATE ION, Phosphoribosylglycinamide synthetase | | Authors: | Baba, S, Kanagawa, M, Kuramitsu, S, Yokoyama, S, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-04-03 | | Release date: | 2007-10-09 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of glycinamide ribonucleotide synthetase, PurD, from thermophilic eubacteria
J.Biochem., 148, 2010
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2YS6
 | | Crystal structure of GAR synthetase from Geobacillus kaustophilus | | Descriptor: | ADENOSINE MONOPHOSPHATE, GLYCINE, Phosphoribosylglycinamide synthetase | | Authors: | Baba, S, Kanagawa, M, Kuramitsu, S, Yokoyama, S, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-04-03 | | Release date: | 2007-10-09 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Crystal structures of glycinamide ribonucleotide synthetase, PurD, from thermophilic eubacteria
J.Biochem., 148, 2010
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3AV3
 | | Crystal structure of glycinamide ribonucleotide transformylase 1 from Geobacillus kaustophilus | | Descriptor: | MAGNESIUM ION, Phosphoribosylglycinamide formyltransferase | | Authors: | Kanagawa, M, Baba, S, Nakagawa, N, Ebihara, A, Kuramitsu, S, Yokoyama, S, Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2011-02-18 | | Release date: | 2012-03-07 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structures and reaction mechanisms of the two related enzymes, PurN and PurU.
J.Biochem., 154, 2013
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3AUF
 | | Crystal structure of glycinamide ribonucleotide transformylase 1 from Symbiobacterium toebii | | Descriptor: | Glycinamide ribonucleotide transformylase 1 | | Authors: | Kanagawa, M, Baba, S, Nagira, T, Kuramitsu, S, Yokoyama, S, Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2011-02-03 | | Release date: | 2012-03-07 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Structures and reaction mechanisms of the two related enzymes, PurN and PurU.
J.Biochem., 154, 2013
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2YWR
 | | Crystal structure of GAR transformylase from Aquifex aeolicus | | Descriptor: | COBALT (II) ION, MAGNESIUM ION, Phosphoribosylglycinamide formyltransferase | | Authors: | Kanagawa, M, Baba, S, Kuramitsu, S, Yokoyama, S, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-04-23 | | Release date: | 2007-10-23 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Structures and reaction mechanisms of the two related enzymes, PurN and PurU.
J.Biochem., 154, 2013
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2YS7
 | | Crystal structure of GAR synthetase from Geobacillus kaustophilus | | Descriptor: | Phosphoribosylglycinamide synthetase | | Authors: | Baba, S, Kanagawa, M, Kuramitsu, S, Yokoyama, S, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-04-03 | | Release date: | 2007-10-09 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Crystal structures of glycinamide ribonucleotide synthetase, PurD, from thermophilic eubacteria
J.Biochem., 148, 2010
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6IZP
 | | Solution structure of the complex of naphthyridine carbamate dimer and an RNA with UGGAA-UGGAA pentad | | Descriptor: | 3-[3-[(7-methyl-1,8-naphthyridin-2-yl)carbamoyloxy]propylamino]propyl ~{N}-(7-methyl-1,8-naphthyridin-2-yl)carbamate, RNA (29-MER) | | Authors: | Nagano, K, Shibata, T, Nakatani, K, Kawai, G. | | Deposit date: | 2018-12-20 | | Release date: | 2019-12-25 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Small molecule targeting r(UGGAA)n disrupts RNA foci and alleviates disease phenotype in Drosophila model
Nat Commun, 12, 2021
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1WKS
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1XWU
 | | Solution structure of ACAUAGA loop | | Descriptor: | 5'-R(*CP*GP*AP*AP*AP*CP*AP*UP*AP*GP*AP*UP*UP*CP*GP*A)-3' | | Authors: | Sakamoto, T, Oguro, A, Kawai, G, Ohtsu, T, Nakamura, Y. | | Deposit date: | 2004-11-02 | | Release date: | 2005-02-15 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | NMR structures of double loops of an RNA aptamer against mammalian initiation factor 4A
Nucleic Acids Res., 33, 2005
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1XWP
 | | Solution structure of AUCGCA loop | | Descriptor: | 5'-R(*GP*GP*AP*GP*AP*UP*CP*GP*CP*AP*CP*UP*CP*CP*A)-3' | | Authors: | Sakamoto, T, Oguro, A, Kawai, G, Ohtsu, T, Nakamura, Y. | | Deposit date: | 2004-11-02 | | Release date: | 2005-02-15 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | NMR structures of double loops of an RNA aptamer against mammalian initiation factor 4A
Nucleic Acids Res., 33, 2005
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5AVM
 | | Crystal structures of 5-aminoimidazole ribonucleotide (AIR) synthetase, PurM, from Thermus thermophilus | | Descriptor: | Phosphoribosylformylglycinamidine cyclo-ligase, SULFATE ION | | Authors: | Kanagawa, M, Baba, S, Watanabe, Y, Nakagawa, N, Ebihara, A, Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2015-06-23 | | Release date: | 2015-11-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures and ligand binding of PurM proteins from Thermus thermophilus and Geobacillus kaustophilus
J.Biochem., 159, 2016
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2D1A
 | | Solution RNA structure model of the HIV-1 dimerization initiation site in the extended-duplex dimer | | Descriptor: | RNA | | Authors: | Baba, S, Takahashi, K, Noguchi, S, Takaku, H, Koyanagi, Y, Yamamoto, N, Kawai, G. | | Deposit date: | 2005-08-15 | | Release date: | 2005-11-01 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution RNA structures of the HIV-1 dimerization initiation site in the kissing-loop and extended-duplex dimers.
J.Biochem.(Tokyo), 138, 2005
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2D17
 | | Solution RNA structure of stem-bulge-stem region of the HIV-1 dimerization initiation site | | Descriptor: | 5'-R(*CP*GP*GP*CP*AP*AP*GP*AP*GP*GP*CP*GP*AP*CP*CP*C)-3', 5'-R(*GP*GP*GP*UP*CP*GP*GP*CP*UP*UP*GP*CP*UP*G)-3' | | Authors: | Baba, S, Takahashi, K, Noguchi, S, Takaku, H, Koyanagi, Y, Yamamoto, N, Kawai, G. | | Deposit date: | 2005-08-15 | | Release date: | 2005-11-01 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution RNA structures of the HIV-1 dimerization initiation site in the kissing-loop and extended-duplex dimers.
J.Biochem.(Tokyo), 138, 2005
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2D1B
 | | Solution RNA structure model of the HIV-1 dimerization initiation site in the kissing-loop dimer | | Descriptor: | RNA | | Authors: | Baba, S, Takahashi, K, Noguchi, S, Takaku, H, Koyanagi, Y, Yamamoto, N, Kawai, G. | | Deposit date: | 2005-08-15 | | Release date: | 2005-11-01 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution RNA structures of the HIV-1 dimerization initiation site in the kissing-loop and extended-duplex dimers.
J.Biochem.(Tokyo), 138, 2005
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2CUW
 | | Crystal Structure of Thermus thermophilus PurS, one of the subunits of Formylglycinamide Ribonucleotide Amidotransferase in the purine biosynthetic pathway | | Descriptor: | PurS | | Authors: | Yanai, H, Kanagawa, M, Sampei, G, Kawai, G, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-30 | | Release date: | 2005-11-30 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structure of Thermus thermophilus PurS, One of the Subunits of Formylglycinamide Ribonucleotide Amidotransferase in the Purine Biosynthetic Pathway
To be Published
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2D18
 | | Solution RNA structure of loop region of the HIV-1 dimerization initiation site in the extended-duplex dimer | | Descriptor: | 5'-R(*GP*CP*UP*GP*AP*AP*GP*UP*GP*CP*AP*CP*AP*CP*GP*GP*C)-3' | | Authors: | Baba, S, Takahashi, K, Noguchi, S, Takaku, H, Koyanagi, Y, Yamamoto, N, Kawai, G. | | Deposit date: | 2005-08-15 | | Release date: | 2005-11-01 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution RNA structures of the HIV-1 dimerization initiation site in the kissing-loop and extended-duplex dimers.
J.Biochem.(Tokyo), 138, 2005
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2D19
 | | Solution RNA structure of loop region of the HIV-1 dimerization initiation site in the kissing-loop dimer | | Descriptor: | 5'-R(*GP*CP*UP*GP*AP*AP*GP*UP*GP*CP*AP*CP*AP*CP*GP*GP*C)-3' | | Authors: | Baba, S, Takahashi, K, Noguchi, S, Takaku, H, Koyanagi, Y, Yamamoto, N, Kawai, G. | | Deposit date: | 2005-08-15 | | Release date: | 2005-11-01 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution RNA structures of the HIV-1 dimerization initiation site in the kissing-loop and extended-duplex dimers.
J.Biochem.(Tokyo), 138, 2005
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3AHU
 | | Crystal structure of YmaH (Hfq) from Bacillus subtilis in complex with an RNA aptamer. | | Descriptor: | 5'-R(*AP*GP*AP*GP*AP*G)-3', Protein hfq | | Authors: | Baba, S, Someya, T, Kumasaka, T, Kawai, G, Nakamura, K. | | Deposit date: | 2010-04-29 | | Release date: | 2011-07-13 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of YmaH (Hfq) from Bacillus subtilis in complex with an RNA aptamer.
To be Published
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2FDT
 | | Solution structure of a conserved RNA hairpin of eel LINE UnaL2 | | Descriptor: | 36-mer | | Authors: | Nomura, Y, Baba, S, Nakazato, S, Sakamoto, T, Kajikawa, M, Okada, N, Kawai, G. | | Deposit date: | 2005-12-14 | | Release date: | 2006-12-05 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure and functional importance of a conserved RNA hairpin of eel LINE UnaL2
Nucleic Acids Res., 34, 2006
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3VIU
 | | Crystal structure of PurL from thermus thermophilus | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | | Authors: | Suzuki, S, Yanai, H, Kanagawa, M, Tamura, S, Watanabe, Y, Fuse, K, Baba, S, Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2011-10-12 | | Release date: | 2012-01-18 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structure of N-formylglycinamide ribonucleotide amidotransferase II (PurL) from Thermus thermophilus HB8
Acta Crystallogr.,Sect.F, 68, 2012
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7FGT
 | | Discovery of DS15060524; Gene targeting chimera (GeneTAC) for the treatment of Friedreich's Ataxia (FRDA) | | Descriptor: | DNA (5'-D(*AP*AP*GP*AP*AP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*CP*TP*T)-3'), ~{N}-[3-[3-(dimethylamino)propylamino]-3-oxidanylidene-propyl]-1-methyl-4-[3-[[1-methyl-4-[[1-methyl-4-[3-[[1-methyl-4-[(1-methylimidazol-2-yl)carbonylamino]pyrrol-2-yl]carbonylamino]propanoylamino]imidazol-2-yl]carbonylamino]pyrrol-2-yl]carbonylamino]propanoylamino]imidazole-2-carboxamide | | Authors: | Takase, N, Kawai, G, Igarashi, W, Katagiri, T. | | Deposit date: | 2021-07-28 | | Release date: | 2022-08-03 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Discovery of DS15060524; Gene targeting chimera (GeneTAC) for the treatment of Friedreich's Ataxia (FRDA)
To be published
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7EXY
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2YWC
 | | Crystal structure of GMP synthetase from Thermus thermophilus in complex with XMP | | Descriptor: | GMP synthase [glutamine-hydrolyzing], XANTHOSINE-5'-MONOPHOSPHATE | | Authors: | Baba, S, Kanagawa, M, Kuramitsu, S, Yokoyama, S, Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-04-20 | | Release date: | 2007-10-23 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of GMP synthetase from Thermus thermophilus
To be Published
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