1Q57
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![BU of 1q57 by Molmil](/molmil-images/mine/1q57) | The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7 | Descriptor: | DNA primase/helicase | Authors: | Toth, E.A, Li, Y, Sawaya, M.R, Cheng, Y, Ellenberger, T. | Deposit date: | 2003-08-06 | Release date: | 2003-11-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7 Mol.Cell, 12, 2003
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1PU6
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![BU of 1pu6 by Molmil](/molmil-images/mine/1pu6) | Crystal structure of H.pylori 3-methyladenine DNA glycosylase (MagIII) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-METHYLADENINE DNA GLYCOSYLASE, BETA-MERCAPTOETHANOL, ... | Authors: | Eichman, B.F, O'Rourke, E.J, Radicella, J.P, Ellenberger, T. | Deposit date: | 2003-06-24 | Release date: | 2003-10-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Crystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated bases Embo J., 22, 2003
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1PU7
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![BU of 1pu7 by Molmil](/molmil-images/mine/1pu7) | Crystal structure of H.pylori 3-methyladenine DNA glycosylase (MagIII) bound to 3,9-dimethyladenine | Descriptor: | 3-METHYLADENINE DNA GLYCOSYLASE, 6-AMINO-3,9-DIMETHYL-9H-PURIN-3-IUM, BETA-MERCAPTOETHANOL | Authors: | Eichman, B.F, O'Rourke, E.J, Radicella, J.P, Ellenberger, T. | Deposit date: | 2003-06-24 | Release date: | 2003-10-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Crystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated bases Embo J., 22, 2003
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2B4J
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![BU of 2b4j by Molmil](/molmil-images/mine/2b4j) | Structural basis for the recognition between HIV-1 integrase and LEDGF/p75 | Descriptor: | GLYCEROL, Integrase (IN), PC4 and SFRS1 interacting protein, ... | Authors: | Cherepanov, P, Ambrosio, A.L, Rahman, S, Ellenberger, T, Engelman, A. | Deposit date: | 2005-09-24 | Release date: | 2005-10-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75 Proc.Natl.Acad.Sci.Usa, 102, 2005
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2AJQ
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![BU of 2ajq by Molmil](/molmil-images/mine/2ajq) | |
1Z19
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![BU of 1z19 by Molmil](/molmil-images/mine/1z19) | Crystal structure of a lambda integrase(75-356) dimer bound to a COC' core site | Descriptor: | 33-MER, 5'-D(*CP*TP*CP*GP*TP*TP*CP*AP*GP*CP*TP*TP*TP*TP*TP*T)-3', 5'-D(P*TP*TP*TP*AP*TP*AP*CP*TP*AP*AP*GP*TP*TP*GP*GP*CP*AP*TP*TP*A)-3', ... | Authors: | Biswas, T, Aihara, H, Radman-Livaja, M, Filman, D, Landy, A, Ellenberger, T. | Deposit date: | 2005-03-03 | Release date: | 2005-06-28 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A structural basis for allosteric control of DNA recombination by lambda integrase. Nature, 435, 2005
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1Z1B
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![BU of 1z1b by Molmil](/molmil-images/mine/1z1b) | Crystal structure of a lambda integrase dimer bound to a COC' core site | Descriptor: | 26-MER DNA, 29-MER DNA, 5'-D(*CP*T*CP*GP*TP*TP*CP*AP*GP*CP*TP*TP*TP*TP*TP*T)-3', ... | Authors: | Biswas, T, Aihara, H, Radman-Livaja, M, Filman, D, Landy, A, Ellenberger, T. | Deposit date: | 2005-03-03 | Release date: | 2005-06-28 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | A structural basis for allosteric control of DNA recombination by lambda integrase. Nature, 435, 2005
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1Z1G
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![BU of 1z1g by Molmil](/molmil-images/mine/1z1g) | Crystal structure of a lambda integrase tetramer bound to a Holliday junction | Descriptor: | 25-MER, 29-MER, 5'-D(*AP*CP*AP*GP*GP*TP*CP*AP*CP*TP*AP*TP*CP*AP*GP*TP*CP*AP*AP*AP*AP*TP*AP*CP*C)-3', ... | Authors: | Biswas, T, Aihara, H, Radman-Livaja, M, Filman, D, Landy, A, Ellenberger, T. | Deposit date: | 2005-03-03 | Release date: | 2005-06-28 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (4.4 Å) | Cite: | A structural basis for allosteric control of DNA recombination by lambda integrase. Nature, 435, 2005
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1AE9
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![BU of 1ae9 by Molmil](/molmil-images/mine/1ae9) | |
1CR0
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![BU of 1cr0 by Molmil](/molmil-images/mine/1cr0) | CRYSTAL STRUCTURE OF THE HELICASE DOMAIN OF THE GENE4 PROTEIN OF BACTERIOPHAGE T7 | Descriptor: | DNA PRIMASE/HELICASE, SULFATE ION | Authors: | Sawaya, M.R, Guo, S, Tabor, S, Richardson, C.C, Ellenberger, T. | Deposit date: | 1999-08-12 | Release date: | 1999-11-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7. Cell(Cambridge,Mass.), 99, 1999
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1BNK
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![BU of 1bnk by Molmil](/molmil-images/mine/1bnk) | HUMAN 3-METHYLADENINE DNA GLYCOSYLASE COMPLEXED TO DNA | Descriptor: | DNA (5'-D(*GP*AP*CP*AP*TP*GP*YRRP*TP*TP*GP*CP*CP*T)-3'), DNA (5'-D(*GP*GP*CP*AP*AP*TP*CP*AP*TP*GP*TP*CP*A)-3'), PROTEIN (3-METHYLADENINE DNA GLYCOSYLASE) | Authors: | Lau, A.Y, Schaerer, O.D, Samson, L, Verdine, G.L, Ellenberger, T. | Deposit date: | 1998-07-29 | Release date: | 1998-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision. Cell(Cambridge,Mass.), 95, 1998
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1CR4
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![BU of 1cr4 by Molmil](/molmil-images/mine/1cr4) | CRYSTAL STRUCTURE OF THE HELICASE DOMAIN OF THE GENE 4 PROTEIN OF BACTERIOPHAGE T7: COMPLEX WITH DTDP | Descriptor: | DNA PRIMASE/HELICASE, SULFATE ION, THYMIDINE-5'-DIPHOSPHATE | Authors: | Sawaya, M.R, Guo, S, Tabor, S, Richardson, C.C, Ellenberger, T. | Deposit date: | 1999-08-12 | Release date: | 1999-11-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7. Cell(Cambridge,Mass.), 99, 1999
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1CR1
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![BU of 1cr1 by Molmil](/molmil-images/mine/1cr1) | CRYSTAL STRUCTURE OF THE HELICASE DOMAIN OF THE GENE 4 PROTEIN OF BACTERIOPHAGE T7: COMPLEX WITH DTTP | Descriptor: | DNA PRIMASE/HELICASE, SULFATE ION, THYMIDINE-5'-TRIPHOSPHATE | Authors: | Sawaya, M.R, Guo, S, Tabor, S, Richardson, C.C, Ellenberger, T. | Deposit date: | 1999-08-12 | Release date: | 1999-11-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7. Cell(Cambridge,Mass.), 99, 1999
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1D5Y
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![BU of 1d5y by Molmil](/molmil-images/mine/1d5y) | CRYSTAL STRUCTURE OF THE E. COLI ROB TRANSCRIPTION FACTOR IN COMPLEX WITH DNA | Descriptor: | DNA (5'-D(*AP*CP*TP*TP*TP*GP*AP*CP*AP*TP*TP*CP*AP*GP*TP*GP*CP*TP*GP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*CP*AP*GP*CP*AP*CP*TP*GP*AP*AP*TP*GP*TP*CP*AP*AP*AP*G)-3'), ROB TRANSCRIPTION FACTOR | Authors: | Kwon, H.J, Bennik, M.H.J, Demple, B, Ellenberger, T. | Deposit date: | 1999-10-12 | Release date: | 2000-04-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the Escherichia coli Rob transcription factor in complex with DNA. Nat.Struct.Biol., 7, 2000
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1E0K
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![BU of 1e0k by Molmil](/molmil-images/mine/1e0k) | gp4d helicase from phage T7 | Descriptor: | DNA HELICASE | Authors: | Singleton, M.R, Sawaya, M.R, Ellenberger, T, Wigley, D.B. | Deposit date: | 2000-03-30 | Release date: | 2000-06-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal Structure of T7 Gene 4 Ring Helicase Indicates a Mechanism for Sequential Hydrolysis of Nucleotides Cell(Cambridge,Mass.), 101, 2000
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1E0J
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![BU of 1e0j by Molmil](/molmil-images/mine/1e0j) | gp4d helicase from phage T7 ADPNP complex | Descriptor: | DNA HELICASE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Singleton, M.R, Sawaya, M.R, Ellenberger, T, Wigley, D.B. | Deposit date: | 2000-03-30 | Release date: | 2000-06-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of T7 Gene 4 Ring Helicase Indicates a Mechanism for Sequential Hydrolysis of Nucleotides Cell(Cambridge,Mass.), 101, 2000
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1EWN
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![BU of 1ewn by Molmil](/molmil-images/mine/1ewn) | CRYSTAL STRUCTURE OF THE HUMAN AAG DNA REPAIR GLYCOSYLASE COMPLEXED WITH 1,N6-ETHENOADENINE-DNA | Descriptor: | 3-METHYL-ADENINE DNA GLYCOSYLASE, DNA (5'-D(*GP*AP*CP*AP*TP*GP*(EDA)P*TP*TP*GP*CP*C)-3'), DNA (5'-D(P*GP*CP*AP*AP*TP*CP*AP*TP*GP*TP*CP*A)-3'), ... | Authors: | Lau, A.Y, Wyatt, M.D, Glassner, B.J, Samson, L.D, Ellenberger, T. | Deposit date: | 2000-04-26 | Release date: | 2000-12-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG. Proc.Natl.Acad.Sci.USA, 97, 2000
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1CR2
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![BU of 1cr2 by Molmil](/molmil-images/mine/1cr2) | CRYSTAL STRUCTURE OF THE HELICASE DOMAIN OF THE GENE 4 PROTEIN OF BACTERIOPHAGE T7: COMPLEX WITH DATP | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA PRIMASE/HELICASE, SULFATE ION | Authors: | Sawaya, M.R, Guo, S, Tabor, S, Richardson, C.C, Ellenberger, T. | Deposit date: | 1999-08-12 | Release date: | 1999-11-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7. Cell(Cambridge,Mass.), 99, 1999
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1F4R
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![BU of 1f4r by Molmil](/molmil-images/mine/1f4r) | CRYSTAL STRUCTURE OF THE HUMAN AAG DNA REPAIR GLYCOSYLASE COMPLEXED WITH 1,N6-ETHENOADENINE-DNA | Descriptor: | 3-METHYL-ADENINE DNA GLYCOSYLASE, DNA (5'-D(*GP*AP*CP*AP*TP*GP*(EDA)P*TP*TP*GP*CP*CP*T)-3'), DNA (5'-D(*GP*GP*CP*AP*AP*TP*CP*AP*TP*GP*TP*CP*A)-3'), ... | Authors: | Lau, A.Y, Wyatt, M.D, Glassner, B.J, Samson, L.D, Ellenberger, T. | Deposit date: | 2000-06-08 | Release date: | 2000-12-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG. Proc.Natl.Acad.Sci.USA, 97, 2000
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1X9N
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![BU of 1x9n by Molmil](/molmil-images/mine/1x9n) | Crystal Structure of Human DNA Ligase I bound to 5'-adenylated, nicked DNA | Descriptor: | 5'-phosphorylated DNA, ADENOSINE MONOPHOSPHATE, DNA ligase I, ... | Authors: | Pascal, J.M, O'Brien, P.J, Tomkinson, A.E, Ellenberger, T. | Deposit date: | 2004-08-23 | Release date: | 2004-11-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Human DNA ligase I completely encircles and partially unwinds nicked DNA. Nature, 432, 2004
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1X9M
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![BU of 1x9m by Molmil](/molmil-images/mine/1x9m) | T7 DNA polymerase in complex with an N-2-acetylaminofluorene-adducted DNA | Descriptor: | 5'-D(*CP*CP*CP*(8FG)P*AP*TP*CP*AP*CP*AP*CP*TP*AP*CP*CP*AP*AP*TP*CP*AP*CP*TP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*AP*GP*TP*GP*AP*TP*TP*GP*GP*TP*AP*GP*TP*GP*TP*GP*AP*(2DT))-3', DNA polymerase, ... | Authors: | Dutta, S, Li, Y, Johnson, D, Dzantiev, L, Richardson, C.C, Romano, L.J, Ellenberger, T. | Deposit date: | 2004-08-23 | Release date: | 2004-10-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis. Proc.Natl.Acad.Sci.USA, 101, 2004
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1X9W
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![BU of 1x9w by Molmil](/molmil-images/mine/1x9w) | T7 DNA polymerase in complex with a primer/template DNA containing a disordered N-2 aminofluorene on the template, crystallized with dideoxy-ATP as the incoming nucleotide. | Descriptor: | 5'-D(*CP*CP*CP*(AFG)*AP*TP*CP*AP*CP*AP*CP*TP*AP*CP*CP*AP*AP*TP*CP*AP*CP*TP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*AP*GP*TP*GP*AP*TP*T*GP*GP*T*AP*GP*TP*GP*TP*GP*AP*(2DT))-3', DNA polymerase, ... | Authors: | Dutta, S, Li, Y, Johnson, D, Dzantiev, L, Richardson, C.C, Romano, L.J, Ellenberger, T. | Deposit date: | 2004-08-24 | Release date: | 2004-10-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis. Proc.Natl.Acad.Sci.Usa, 101, 2004
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2A1J
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![BU of 2a1j by Molmil](/molmil-images/mine/2a1j) | Crystal Structure of the Complex between the C-Terminal Domains of Human XPF and ERCC1 | Descriptor: | DNA excision repair protein ERCC-1, DNA repair endonuclease XPF, MERCURY (II) ION | Authors: | Tsodikov, O.V, Enzlin, J.H, Scharer, O.D, Ellenberger, T. | Deposit date: | 2005-06-20 | Release date: | 2005-08-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1. Proc.Natl.Acad.Sci.Usa, 102, 2005
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1ZYQ
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![BU of 1zyq by Molmil](/molmil-images/mine/1zyq) | T7 DNA polymerase in complex with 8oG and incoming ddATP | Descriptor: | 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*CP*CP*(8OG)P*CP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*(DDG))-3', ... | Authors: | Brieba, L.G, Kokoska, R.J, Bebenek, K, Kunkel, T.A, Ellenberger, T. | Deposit date: | 2005-06-10 | Release date: | 2005-11-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A lysine residue in the fingers subdomain of t7 DNA polymerase modulates the miscoding potential of 8-oxo-7,8-dihydroguanosine. Structure, 13, 2005
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2HII
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![BU of 2hii by Molmil](/molmil-images/mine/2hii) | heterotrimeric PCNA sliding clamp | Descriptor: | PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405) | Authors: | Pascal, J.M, Tsodikov, O.V, Ellenberger, T. | Deposit date: | 2006-06-29 | Release date: | 2006-11-07 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA. Mol.Cell, 24, 2006
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