1ZYQ

T7 DNA polymerase in complex with 8oG and incoming ddATP

Summary for 1ZYQ

Related1T7P
Descriptor5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*(DDG))-3', 5'-D(*CP*CP*CP*(8OG)P*CP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', DNA polymerase, ... (7 entities in total)
Functional Keywords8og, fidelity, transferase-electron transport-dna complex, transferase/electron transport/dna
Biological sourceEnterobacteria phage T7
More
Total number of polymer chains4
Total molecular weight105970.63
Authors
Brieba, L.G.,Kokoska, R.J.,Bebenek, K.,Kunkel, T.A.,Ellenberger, T. (deposition date: 2005-06-10, release date: 2005-11-22, Last modification date: 2011-07-13)
Primary citation
Brieba, L.G.,Kokoska, R.J.,Bebenek, K.,Kunkel, T.A.,Ellenberger, T.
A lysine residue in the fingers subdomain of t7 DNA polymerase modulates the miscoding potential of 8-oxo-7,8-dihydroguanosine.
Structure, 13:1653-1659, 2005
PubMed: 16271888 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2005.07.020
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.224151.3%4.3%5.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report